Pathophysiology - Elsevier eBook on VitalSource, 8th Edition

• NEW! Added coverage of rare diseases and epigenetics further explore genetic disease traits.
• NEW! Chapter on obesity and nutritional disorders thoroughly covers these growing global concerns.
• NEW! Over 50 new or heavily revised illustrations highlight pathophysiology concepts and visually engage the reader.
• Over 1,300 full-color illustrations and photographs depict the clinical manifestations of disease and disease processes — more than in any other pathophysiology text.
• The most comprehensive and authoritative pathophysiology text on the market provides unparalleled coverage of Pathophysiology content
• NEW! More than 30 new 3D animations on Evolve bring difficult concepts to life for a new perspective on disease processes.
• Consistent presentation of diseases includes pathophysiology, clinical manifestations, and evaluation and treatment.
• Lifespan content includes ten separate pediatric chapters and special sections with aging and pediatrics content.
• Outstanding authors Kathryn McCance and Sue Huether have extensive backgrounds as researchers and instructors, and utilize expert contributors, consultants, and reviewers in developing this edition.
• Algorithms and flowcharts of diseases and disorders make it easy for students to follow the sequential progression of disease processes.
• Additional What’s New boxes highlight the most current research and clinical development.
• Nutrition and Disease boxes explain the link between concepts of health promotion and disease.
• Chapter summary reviews provide concise synopses of the main points of each chapter.

• NEW! Chapter on obesity and nutritional disorders thoroughly covers these growing global concerns.
• NEW! Added coverage of rare diseases and epigenetics further explore genetic disease traits.
• NEW! Over 50 new or heavily revised illustrations visually highlight pathophysiology concepts.
• NEW! More than 30 new 3D animations on Evolve bring difficult concepts to life for a new perspective on disease processes.

Part 1: CENTRAL CONCEPTS OF PATHOPHYSIOLOGY: CELLS AND TISSUES Unit I: THE CELL 1. Cellular Biology 2. Altered Cellular and Tissue Biology: Environmental Agents 3. The Cellular Environment: Fluids and Electrolytes, Acids and Bases

Unit II: GENES AND GENE-ENVIRONMENT INTERACTION 4. Genes and Genetic Diseases 5. Genes, Environment-Lifestyle, and Common Diseases 6. Epigenetics and Disease

Unit III: MECHANISMS OF SELF-DEFENSE 7. Innate Immunity: Inflammation 8. Adaptive Immunity 9. Alterations in Immunity and Inflammation 10. Infection 11. Stress and Disease

Unit IV. CELLULAR PROLIFERATION: CANCER 12. Cancer Biology 13. Cancer Epidemiology 14. Cancer in Children

Part 2: PATHOPHYSIOLOGIC ALTERATIONS: ORGANS AND SYSTEMS Unit V: THE NEUROLOGIC SYSTEM 15. Structure and Function of the Neurologic System 16. Pain, Temperature Regulation, Sleep, and Sensory Function 17. Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function 18. Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction 19. Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders 20. Alterations of Neurologic Function in Children

Unit VI: THE ENDOCRINE SYSTEM 21. Mechanisms of Hormonal Regulation 22. Alterations of Hormonal Regulation 23. Obesity and Disorders of Nutrition NEW CHAPTER

Unit VII: THE REPRODUCTIVE SYSTEMS 24. Structure and Function of the Reproductive Systems 25. Alterations of the Female Reproductive System 26. Alterations of the Male Reproductive System 27. Sexually Transmitted Infections

Unit VIII: THE HEMATOLOGIC SYSTEM 28. Structure and Function of the Hematologic System 29. Alterations of Erythrocyte, Platelet, and Hemostatic Function 30. Alterations of Leukocyte and Lymphoid Function 31. Alterations of Hematologic Function in Children

Unit IX: THE CARDIOVASCULAR AND LYMPHATIC SYSTEMS 32. Structure and Function of the Cardiovascular and Lymphatic Systems 33. Alterations of Cardiovascular Function 34. Alterations of Cardiovascular Function in Children

Unit X: THE PULMONARY SYSTEM 35. Structure and Function of the Pulmonary System 36. Alterations of Pulmonary Function 37. Alterations of Pulmonary Function in Children

Unit XI: THE RENAL AND UROLOGIC SYSTEMS 38. Structure and Function of the Renal and Urologic Systems 39. Alterations of Renal and Urinary Function 40. Alterations of Renal and Urinary Tract Function in Children

Unit XII: THE DIGESTIVE SYSTEM 41. Structure and Function of the Digestive System 42. Alterations of Digestive Function 43. Alterations of Digestive Function in Children

Unit XIII: THE MUSCULOSKELETAL SYSTEM 44. Structure and Function of the Musculoskeletal System 45. Alterations of Musculoskeletal Function 46. Alterations of Musculoskeletal Function in Children

Unit XIV: THE INTEGUMENTARY SYSTEM 47. Structure, Function, and Disorders of the Integument 48. Alterations of the Integument in Children

Unit XV: MULTIPLE INTERACTING SYSTEMS 49. Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults 50. Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children