Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics Elsevier eBook on VitalSource, 8th Edition

• Condensed version of the clinical chemistry "bible" offers the same authoritative and well-presented content in a much more focused and streamlined manner.
• Coverage of analytical techniques and instrumentation includes optical techniques, electrochemistry, electrophoresis, chromatography, mass spectrometry, enzymology, immunochemical techniques, microchips, automation, and point of care testing.
• Updated chapters on molecular diagnostics cover the principles of molecular biology, nucleic acid techniques and applications, and genomes and nucleic acid alterations, reflecting the changes in this rapidly evolving field.
• Learning objectives, key words, and review questions are included in each chapter to support learning.
• More than 500 illustrations plus easy-to-read tables help readers better understand and remember key concepts.

• NEW! Clinical Cases from The Coakley Collection use real-life scenarios to demonstrate how concepts from the text will come in to play in real life practice.
• NEW! Questions from The Deacon’s Challenge of Biochemical Calculations Collection help reinforce concepts and help readers’ critical thinking skills.
• NEW! Updated content throughout the text keeps readers up to date on the latest techniques, instrumentation, and technologies.
• NEW! New lead author Nader Rifai lends his expertise as the Director of Clinical Chemistry at Children’s Hospital in Boston, the Editor-in-Chief of the journal Clinical Chemistry, and a Professor of Pathology at Harvard University.

PART I: PRINCIPLES OF LABORATORY MEDICINE 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine 2. Analytical and Clinical Evaluation of Methods 3. Preanalytical Variation 4. Biological Variation 5. Establishment and Use of Reference Values 6. Specimen Collection, Processing, and Other Preanalytical Variables 7. Quality Management 8. Principles of Basic Techniques and Laboratory Safety

PART II: ANALYTICAL TECHNIQUES AND INSTRUMENTATION 9. Optical Techniques  10. Electrochemistry and Chemical Sensors 11. Electrophoresis 12. Chromatography  13. Mass Spectrometry  14. Enzyme and Rate Analyses  15. Immunochemical Techniques  16. Automation 17. Point-of-Care Testing

PART III:  ANALYTES 18. Amino Acids, Peptides, and Proteins 19. Serum Enzymes 20. Tumor Markers 21. Kidney Function Tests - Creatinine, GFR, Urea, and Uric Acid 22. Carbohydrates 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors 24. Electrolytes and Blood Gases 25. Hormones 26. Catecholamines and Serotonin 27. Vitaminsand Trace Elements, 28. Hemoglobin, Iron, and Bilirubin 29. Porphyrins and Porphyrias  30. Therapeutic Drug  Monitoring 31. Clinical Toxicology  32. ToxicElements

PART IV:  PATHOPHYSIOLOGY 33. Diabetes Mellitus 34. Cardiovascular Disease 35. Kidney Disease  36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism 37. Liver Disease  38. Gastrointestinal and Pancreatic Diseases   39. Disorders of Bone and Mineral Metabolism 40. Disorders of the Pituitary Gland 41. Disorders of the Adrenal Cortex  42. Thyroid Disorders 43. Reproduction-Related Disorders  44. Pregnancy and Prenatal Testing  45. Newborn Screening and Inborn Errors of Metabolism 46. Pharmacogenetics

PART V:  MOLECULAR DIAGNOSTICS   47. Molecular Principles 48. Molecular Techniques 49. Molecular Applications

Appendix Reference Information for the Clinical Laboratory