More than 400 chapters authored by a veritable "Who’s Who" of modern medicine
A practical, templated organization with an emphasis on evidence-based references
Thousands of algorithms, figures, and tables that make its information readily accessible
Over 90 supplementary videos, heart sounds, and key references
Available in print and on a variety of electronic devices
Supplemented by over 1500 board-style questions and answers to help you prepare for certification and recertification examinations
Continuously updated by Lee Goldman, MD
Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices
SECTION 1: SOCIAL AND ETHICAL ISSUES IN MEDICINE 1. Approach to Medicine, the Patient, and the Medical Profession: Medicine as a Learned and Humane Profession 2. Bioethics in the Practice of Medicine 3. Care of Dying Patients and Their Families 4. Cultural and Social Disparities in Health Care 5. Global Health SECTION 2: PRINCIPLES OF EVALUATION AND MANAGEMENT 6. Approach to the Patient: History and Physical Examination 7. Approach to the Patient with Abnormal Vital Signs 8. Statistical Interpretation of Data and Using Data for Clinical Decisions 9. Measuring Health and Health Care 10. Quality of Care and Patient Safety 11. Comprehensive Chronic Disease Management SECTION 3: PREVENTIVE AND ENVIRONMENTAL ISSUES 12. The Periodic Health Examination 13. Physical Activity 14. Adolescent Medicine 15. Immunization 16. Principles of Occupational and Environmental Medicine 17. Radiation Injury 18. Bioterrorism 19. Chronic Poisoning: Trace Metals and Others SECTION 4: AGING AND GERIATRIC MEDICINE 20. Epidemiology of Aging: Implications of the Aging of Society 21. Geriatric Assessment 22. Common Clinical Sequelae of Aging 23. Urinary Incontinence 24. Neuropsychiatric Aspects of Aging 25. Delirium in the Older Patient SECTION 5: CLINICAL PHARMACOLOGY 26. Principles of Drug Therapy 27. Pain 28. Biology of Addiction 29. Nicotine and Tobacco 30. Alcohol Use Disorders 31. Drugs of Abuse 32. Synthetic Immunomodulatory Drug Including Glucocorticoids 33. Biologic Agents and Signaling Inhibitors 34. Complementary, Alternative, and Integrative Medicine SECTION 6: GENETICS 35. Principles of Genetics 36. Clinical Genomics – Genome Structure and Variation 37. Applications of Molecular Technologies to Clinical Medicine 38. Regenerative Medicine, Cell, and Gene Therapies SECTION 7: PRINCIPLES OF IMMUNOLOGY AND INFLAMMATION 39. The Innate Immune System 40. The Adaptive Immunse System 41. Mechanisms of Immune-Mediated Tissue Injury 42. Mechanisms of Inflammation and Tissue Repair 43. Transplantation Immunology 44. Complement System in Disease SECTION 8: CARDIOVASCULAR DISEASE 45. Approach to the Patient with Possible Cardiovascular Disease 46. Epidemiology of Cardiovascular Disease 47. Cardiac and Circulatory Function 48. Electrocardiography 49. Echocardiography 50. Noninvasive Cardiac Imaging 51. Catheterization and Angiography 52. Heart Failure: Pathophysiology and Diagnosis 53. Heart Failure: Management and Prognosis 54. Diseases of the Myocardium and Endocardium 55. Principles of Electrophysiology 56. Approach to the Patient with Suspected Arrhythmia 57. Approach to Cardiac Arrest and Life-Threatening Arrhythmias 58. Cardiac Arrhythmias with Supraventricular Origin 59. Ventricular Arrhythmias 60. Electrophysiologic Interventional Procedures and Surgery 61. Congenital Heart Disease in Adults 62. Angina Pectoris and Stable Ischemic Heart Disease 63. Acute Coronary Syndrome: Unstable Angina and Non-ST Elevation Myocardial Infarction 64. ST Elevation Acute Myocardial Infarction and Complications of Myocardial Infarction 65. Interventional and Surgical Treatment of Coronary Artery Disease 66. Valvular Heart Disease 67. Infective Endocarditis 68. Pericardial Diseases 69. Diseases of the Aorta SECTION 9: VASCULAR MEDICINE 70. Arterial Hypertension 71. Atherosclerotic Peripheral Arterial Disease 72. Other Peripheral Arterial Diseases 73. Thrombotic Disorders: Hypercoagulable States 74. Venous Thrombosis and Embolism 75. Pulmonary Hypertension 76. Antithrombotic and Antiplatelet Therapy SECTION 10: RESPIRATORY DISEASES 77. Approach to the Patient with Respiratory Disease 78. Imaging in Pulmonary Disease 79. Respiratory Function and Testing 80. Disorders of Ventilatory Control 81. Asthma 82. Chronic Obstructive Pulmonary Disease 83. Cystic Fibrosis 84. Bronchiectasis, Atelectasis, Cysts, and Localized Lung Disorders 85. Alveolar Filling Disorders 86. Interstitial Lung Disease 87. Occupational Lung Disease 88. Physical and Chemical Injuries of the Lung 89. Sarcoidosis 90. Acute Bronchitis and Tracheitis 91. Overview of Pneumonia 92. Diseases of the Diaphragm, Chest Wall, Pleura, and Mediastinum 93. Interventional and Surgical Approaches to Lung Disease SECTION 11: CRITICAL CARE MEDICINE 94. Approach to the Patient in a Critical Care Setting 95. Respiratory Monitoring in Critical Care 96. Acute Respiratory Failure 97. Mechanical Ventilation 98. Approach to the Patient with Shock 99. Cardiogenic Shock 100. Shock Syndromes Related to Sepsis 101. Disorders Due to Heat and Cold 102. Acute Poisoning 103. Medical Aspects of Trauma and Burns 104. Envenomation, Bites, and Stings 105. Rhabdomyolysis SECTION 12: RENAL AND GENITOURINARY DISEASES 106. Approach to the Patient with Renal Disease 107. Structure and Function of the Kidneys 108. Disorders of Sodium and Water Homeostasis 109. Potassium Disorders 110. Acid-Base Disorders 111. Disorders of Magnesium and Phosphorus 112. Acute Kidney Injury 113. Glomerular Disorders and Nephrotic Syndromes 114. Tubulointerstitial Diseases 115. Diabetes and the Kidney 116. Vascular Disorders of the Kidney 117. Nephrolithiasis 118. Cystic Kidney Diseases 119. Hereditary Nephropathies and Developmental Abnormalities of the Urinary Tract 120. Benign Prostatic Hyperplasia and Prostatitis 121. Chronic Kidney Disease 122. Treatment of Irreversible Renal Failure SECTION 13: GASTROINTESTINAL DISEASES 123. Approach to the Patient with Gastrointestinal Disease 124. Diagnostic Imaging Procedures in Gastroenterology 125. Gastrointestinal Endoscopy 126. Gastrointestinal Hemorrhage 127. Disorders of Gastrointestinal Motility 128. Functional Gastrointestinal Disorders: Irritable Bowel Syndrome, Dyspepsia, Esophageal Chest Pain, and Heartburn 129. Diseases of the Esophagus 130. Acid Peptic Disease 131. Approach to the Patient with Diarrhea and Malabsorption 132. Inflammatory Bowel Disease 133. Inflammatory and Anatomic Diseases of the Intestine, Peritoneum, Mesentery, and Omentum 134. Vascular Diseases of the Gastrointestinal Tract 135. Pancreatitis
Lee Goldman, MD, Professor of Medicine and Epidemiology Dean Emeritus of the Faculties of Health Sciences and Medicine Columbia University Medical Center, New York and Andrew I. Schafer, MD, Professor of Medicine, Director, Richard T. Silver Center for Myeloproliferative Neoplasms, Weill Cornell Medical College, New York, New York
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