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cover image - Kelley and Firestein's Textbook of Rheumatology - Elsevier eBook on VitalSource,10th Edition
ISBN: 9780323680851
Page Count: 2288
Imprint: Elsevier
List Price: $358.99

Kelley and Firestein's Textbook of Rheumatology - Elsevier eBook on VitalSource, 10th Edition

by Gary S. Firestein, MD, Ralph C. Budd, MD, Sherine E Gabriel, MD, MSc, Iain B McInnes, PhD, FRCP, FRSE, FMedSci and James R O'Dell, MD

Elsevier eBook on VitalSource

cover image - Kelley and Firestein's Textbook of Rheumatology - Elsevier eBook on VitalSource,10th Edition
ISBN: 9780323680851
Page Count: 2288
Imprint: Elsevier
List Price: $358.99
Was $358.99
Now $341.04
Or $0.00 with a valid access code
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Consult the definitive resource in rheumatology for an in-depth understanding of scientific advances as they apply to clinical practice. Masterfully edited by Drs. Gary S. Firestein, Ralph C. Budd, Sherine E. Gabriel, Iain B. McInnes, and James R. O'Dell, and authored by internationally renowned scientists and clinicians in the field, Kelley and Firestein’s Textbook of Rheumatology, 10th Edition, delivers the knowledge you need for accurate diagnoses and effective patient care. From basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes, this state-of-the-art reference provides a global, authoritative perspective on the manifestations, diagnosis and treatment of rheumatic diseases.

    • An ideal balance of the basic science you need to know and how to apply that information to clinical practice.
    • An integrated chapter format allows you to review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance for the full range of rheumatologic diseases and syndromes.
    • Videos online demonstrate the complete musculoskeletal exam, including abnormal findings and the arthroscopic presentation of diseased joints.
    • New content on the latest diagnostic perspectives and approaches to therapy, including five brand-new chapters: Metabolic Regulation of Immunity, Principles of Signaling, Research Methods in the Rheumatic Diseases, Novel Intracellular Targeting Agents, and IgG4-Related Diseases.
    • New and expanded chapter topics on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies.
    • More schematic diagrams clearly summarize information and facilitate understanding.
  • 1 Biology of the Normal Joint

    2 Synovium

    3 Cartilage and Chondrocytes

    4 Biology, Physiology, and Morphology of Bone

    5 Muscle: Anatomy, Physiology, and Biochemistry

    6 Biomechanics

    7 Tissue Engineering

    8 Proteinases and Matrix Degradation

    9 Dendritic Cells


    11 Neutrophils

    12 T Lymphocytes

    13 B Cells

    14 Fibroblasts and Fibroblast-like Synoviocytes

    15 Mast Cells

    16 Platelets and Rheumatic Diseases

    17 Innate Immunity

    18 ADAPTIVE IMMUNITY and Organization of Lymphoid Tissues

    19 Autoimmunity


    21 Genetics of Rheumatic Diseases

    22 Epigenetics of rheumatic diseases

    23 Complement System

    24 Prostaglandins, Leukotrienes, and Related Compounds

    25 Cell Recruitment and Angiogenesis

    26 Cytokines


    28 Cell Survival and Death in Rheumatic Diseases

    29 Animal Models of Rheumatic Diseases

    30 Neural regulation of Pain and Inflammation



    33 Assessment of Health Outcomes IN RHEUMATIC DISEASES

    34 Biologic Markers

    35 Occupational and Recreational MSK Disorders

    36 Cardiovascular Risk in Rheumatic Disease

    37 Cancer Risk in Rheumatic Diseases

    38 Introduction to Physical Medicine, Physical Therapy and Rehabilitation

    39 Pregnancy and Rheumatic Diseases

    40 History and Physical Examination of the Musculoskeletal System



    43 The Skin and Rheumatic Diseases

    44 The Eye and Rheumatic Diseases

    45 Neck Pain

    46 Shoulder Pain

    47 Low Back Pain

    48 Hip and Knee Pain

    49 Ankle and Foot Pain

    50 Hand and Wrist Pain

    51 Temporomandibular Joint Pain

    52 Fibromyalgia

    53 Synovial Fluid Analysis, Synovial Biopsy, and Synovial Pathology

    54 Arthrocentesis and Injection of Joints and Soft Tissue

    55 Antinuclear Antibodies

    56 Autoantibodies in rheumatoid arthritis

    57 Acute Phase Reactants

    58 Imaging Modalities in Rheumatic Disease

    59 Prostanoid Biology and its Therapeutic Targeting

    60 Glucocorticoid Therapy

    61 Traditional DMARDS: Methotrexate, Leflunomide, Sulfasalazine, and Hydroxychloroquine and Combination Therapies

    62 TRADITIONAL Immunoregulatory Drugs

    63 Anticytokine Therapies

    64 Cell Targeted Biologics


    66 Urate Lowering Therapy

    67 Analgesic Agents in Rheumatic Diseases

    68 Nutrition and Rheumatic Disease

    69 Etiology and Pathogenesis of Rheumatoid Arthritis

    70 Clinical Features of Rheumatoid Arthriti

    71 Treatment of Rheumatoid Arthritis

    72 Early Synovitis and Early Undifferentiated Arthritis

    73 Sjogren's Syndrome

    74 Etiology and Pathogenesis of Spondyloarthropathies

    75 Ankylosing Spondylitis

    76 Undifferentiated Spondyloarthritis and Reactive Arthritis

    77 Psoriatic Arthritis

    78 Enteropathic Arthritis

    79 Etiology and Pathogenesis of SLE

    80 Clinical Features of SLE

    81 Treatment of SLE

    82 Antiphospholipid Syndrome

    83 Etiology and Pathogenesis of Scleroderma

    84 Clinical Features and Treatment of Scleroderma

    85 Inflammatory Diseases of Muscle and Other Myopathies

    86 Overlap Syndromes

    87 Classification and Epidemiology of Systemic Vasculitis

    88 Giant Cell Arteritis, Polymyalgia Rheumatica, and Takayasu's Arteritis

    89 Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

    90 Polyarteritis and Related Disorders

    91 Immune Complex-Mediated Small Vessel Vasculitis

    92 Isolated Angiitis of the Nervous System

    93 Bechet's Disease

    94 Etiology and Pathogenesis of Gout and Hyperuricemia

    95 Clinical Features and Treatment of Gout

    96 Calcium Crystal Diseases: Calcium Pyrophosphate Dihydrate and Basic Calcium Phosphate

    97 Familial Autoinflammatory Syndromes

    98 Etiology and Pathogenesis of Osteoarthritis

    99 Clinical Features of Osteoarthritis

    100 Treatment of Osteoarthritis

    101 Metabolic Bone Disease

    102 Proliferative Bone Disease

    103 Osteonecrosis

    104 Relapsing Polychondritis

    105 Heritable Diseases of Connective Tissue

    106 Etiology and Pathogenesis of Juvenile Idiopathic Arthritis

    107 Treatment of Juvenile Inflammatory Arthritis

    108 SLE, Juvenile Dermatomyositis, Scleroderma and Vasculitis

    109 Bacterial Arthritis

    110 Lyme Disease

    111 Mycobacterial Infections of Bones and Joints

    112 Fungal Infections of Bones and Joints

    113 Rheumatic Manifestations of HIV Infection

    114 Viral Arthritis

    115 Rheumatic Fever and Post-Streptococcal Arthritis

    116 Amyloidosis

    117 Sarcoidosis

    118 Hemachromotosis

    119 Hemophilic Arthropathy

    120 Rheumatic Manifestations of Hemoglobinopathies


    122 Arthritis Accompanying Endocrine and Metabolic Disorders

    123 Musculoskeletal Syndromes Associated with Malignancy

    124 Tumors and Tumor-like Lesions of Joints and Related Structures

  • Gary S. Firestein, MD, Distinguished Professor of Medicine, Dean and Associate Vice Chancellor of Translational Medicine, University of California San Diego School of Medicine, La Jolla, California, Ralph C. Budd, MD, Professor of Medicine and Microbiology and Molecular Genetics, Director, Vermont Center for Immunology and Infectious Diseases, University of Vermont College of Medicine Distinguished University Professor, The University of Vermont College of Medicine, Burlington, Vermont, Sherine E Gabriel, MD, MSc, Professor and Dean, Rutgers Robert Wood Johnson Medical School, CEO, Robert Wood Johnson Medical Group, Emeritus Professor, Mayo Clinic, New Brunswick, New Jersey, Iain B McInnes, PhD, FRCP, FRSE, FMedSci, Muirhead Professor of Medicine, Arthritis Research UK Professor of Rheumatology, Director of Institute of Infection,Immunity, and Inflammation, College of Medical, Veterinary, and Life Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom and James R O'Dell, MD, Bruce Professor and Vice Chairman of Internal Medicine, University of Nebraska Medical Center, Chief of Rheumatology, Department of Medicine, Omaha Veterans Affairs, Omaha, Nebraska
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