cover image - Nathan and Oski's Hematology and Oncology of Infancy and Childhood - Elsevier eBook on VitalSource,8th Edition
ISBN: 9780323680936
Page Count: 2752
Imprint: Saunders
List Price: $425.00

Nathan and Oski's Hematology and Oncology of Infancy and Childhood - Elsevier eBook on VitalSource, 8th Edition

by Stuart H. Orkin, MD, David G. Nathan, MD, David Ginsburg, MD, A. Thomas Look, MD, David E. Fisher, MD, PhD and Samuel Lux, MD
Elsevier eBook on VitalSource
cover image - Nathan and Oski's Hematology and Oncology of Infancy and Childhood - Elsevier eBook on VitalSource,8th Edition
ISBN: 9780323680936
Page Count: 2752
Imprint: Saunders
List Price: $425.00
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 Written by the leading names in pediatric oncology and hematology, Nathan and Oski’s Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, this exciting full-color, two-volume set brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children.

    • Form a definitive diagnosis and create the best treatment plans possible with comprehensive coverage of all pediatric cancers, including less-common tumors, as well as all hematologic disorders, including newly recognized ones.
    • Develop a thorough, understanding of the underlying science of diseases through summaries of relevant pathophysiology balanced with clear, practical clinical guidance. Nathan and Oski’s is the only comprehensive product on the market that relates pathophysiology in such depth to hematologic and oncologic diseases affecting children.
    • Quickly and effortlessly access the key information you need with the help of a consistent organization from chapter to chapter and from volume to volume.
    • Stay at the forefront of your field thanks to new and revised chapters covering topics such as paroxysmal nocturnal hemoglobinuria, lysosomal storage diseases, childhood genetic predisposition to cancer, and oncology informatics.
    • Learn about the latest breakthroughs in diagnosis and management, making this the most complete guide in pediatric hematology and oncology.
    • Discover the latest in focused molecularly targeted therapies derived from the exponential growth of knowledge about basic biology and genetics underlying the field.
    • Rely on it anytime, anywhere! Access the full text, images, and more at Expert Consult.
  • Section I Neonatal Hematology

    1. Anatomy and Physiology of Hematopoiesis

    2. The Neonatal Erythrocyte and Its Disorders

    3. Immune Hemolytic Disease

    4. Neonatal Jaundice and Disorders of Bilirubin Metabolism

    5. Hemostasis in the Newborn and Infant

    Section II Bone Marrow Failure

    6. Acquired Aplastic Anemia and Pure Red Cell Aplasia

    7. Inherited Bone Marrow Failure Syndromes

    8. Principles of Bone Marrow and Stem Cell Transplantation

    Section III Disorders of Erythrocyte Production

    9. Diagnostic Approach to the Anemic Patient

    10. Megaloblastic Anemia

    11. Disorders of Iron and Copper Metabolism, Sideroblastic Anemias and Lead Toxicity

    12. Porphyrias

    Section IV Hemolytic Anemias

    13. Autoimmune Hemolytic Anemia

    14. Paroxysmal Nocturnal Hemoglobinuria

    15. Red Cell Membrane

    16. Disorders of the Red Cell Membrane

    17. Pyruvate Kinase Deficiency and Disorders of Glycolysis

    18. Glucose-6-Phosphate Dehydrogenase Deficiency

    19. Normal and Abnormal Hemoglobins

    Section V Disorders of Hemoglobin

    20. Sickle Cell Disease

    21. Thalassemias

    Section VI Phagocyte System

    22. Phagocyte System and Disorders of Granulopoiesis and Granulocyte Function

    Section VII Immune System

    23. Immune Response

    24. Primary Immunodeficiency Diseases

    Section VIII Storage Diseases

    25. Lysosomal Storage Diseases

    Section IX Hemostasis

    26. Platelets and the Vessel Wall

    27. Blood Coagulation

    28. Molecular Basis of Fibrinolysis

    29. Approach to the Child with a Suspected Bleeding Disorder

    30. Inherited Platelet Disorders

    31. Hemophilia and von Willebrand Disease

    32. Rare Hereditary Coagulation Factor Abnormalities

    33. Inherited Disorders of Thrombosis and Fibrinolysis

    34. Acquired Platelet Defects

    35. Acquired Disorders of Hemostasis

    Section X Supportive Therapy

    36. Transfusion Medicine

    Section XI Hematologic Manifestations of Systemic Diseases

    37. Hematological Manifestations of Systemic Diseases

    38. Hematology Manifestations of Systemic Diseases in Children of the Developing World

    Section XII Biology of Cancer

    39. Origins and Evolution of Pediatric Cancer

    40. Epidemiology of Leukemia in Childhood

    41. Informatics

    42. Genetic Predisposition to Cancer

    43. Genetic and Epigenetics of Childhood Cancers

    44. Targeted Therapies in Oncology

    45. Cytogenetic and Molecular Pathology of Pediatric Cancer 

    Section XIII Pediatric Cancer Therapeutics

    46. Cancer Chemotherapy for Pediatric Patients

    47. Immunotherapy of Cancer

    48. Pediatric Radiation Oncology

    48. Pediatric Surgical Oncology 

    Section XIV Hematologic Malignancy

    50. Acute Lymphoblastic Leukemia 

    51. Pediatric Myeloid Leukemia, Myelodysplasia, and Myeloproliferative Disease

    52. Infant Leukemias

    53. Pediatric Lymphoma

    Section XV Solid Tumors

    54. Neuroblastoma

    55. Pediatric Renal Tumors

    56. Retinoblastoma

    57. Tumors of the Brain and Spinal Cord 

    58. Hepatoblastoma and Other Liver Tumors in Children

    59. Rhabdomyosarcoma

    60. Nonrhabdomyosarcoma Soft Tissue Sarcomas and Other Soft Tissue Tumors 

    61. Ewing Sarcoma

    62. Osteosarcoma

    63. Pediatric Germ Cell Tumors

    64. Histiocytoses

    65. Rare Tumors of Childhood

    66. Imaging in the Evaluation and Management of Childhood Cancer

    Section XVI Supportive Care

    67. Infectious Disease in the Pediatric Cancer Patient 

    68. Oncologic Emergencies

    69. Nursing Care of Patients with Childhood Cancer 

    70. Palliative Care in Pediatric Oncology

    71. Symptom Management in Children with Cancer

    72. Childhood Cancer Survivorship

    73. Psychosocial Care of the Child and Family

    74. Ethical Considerations in Pediatric Oncology Clinical Trials 

    Appendices: Reference Values in Infancy and Childhood

  • Stuart H. Orkin, MD, David G Nathan Professor of Pediatrics, Harvard Medical School; Chair, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston Children's Hospital; Investigator, Howard Hughes Medical Institute, Boston, Massachusetts, David G. Nathan, MD, President Emeritus, Dana-Farber Cancer Institute, Physician-in-Chief Emeritus, Boston Children's Hospital; Stranahan Distinguished Professor of Pediatrics and Professor of Medicine, Harvard Medical School, Boston, Massachusetts, David Ginsburg, MD, James V Neel Distinguished University Professor, Departments of Internal Medicine, Pediatrics, and Communicable Diseases, and Human Genetics, Investigator, Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor, Michigan, A. Thomas Look, MD, Professor of Pediatrics, Harvard Medical School; Vice Chair for Research, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston Children's Hospital, Boston, Massachusetts, David E. Fisher, MD, PhD, Chief, Department of Dermatology, Director, Cutaneous Biology Research Center, Massachusetts General Hospital; Director, Melanoma Program, Massachusetts General Hospital Cancer Center, Boston, Massachusetts and Samuel Lux, MD, Robert A Stranahan Professor of Pediatrics, Harvard Medical School; Chief Emeritus, Hematology/Oncology, Boston Children's Hospital, Boston, Massachusetts
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