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cover image - Cell Biology Elsevier eBook on VitalSource,4th Edition
ISBN: 9780323758048
Publication Date: 02-21-2023
Page Count: 944
Imprint: Elsevier
List Price: $125.99

Cell Biology Elsevier eBook on VitalSource, 4th Edition

by Thomas D. Pollard, MD, William C. Earnshaw, PhD, FRS, Jennifer Lippincott-Schwartz, PhD and Graham Johnson, MA, PhD, CMI

Elsevier eBook on VitalSource

cover image - Cell Biology Elsevier eBook on VitalSource,4th Edition
ISBN: 9780323758048
Publication Date: 02-21-2023
Page Count: 944
Imprint: Elsevier

$125.99

Or $0.00 with a valid access code

Reader-friendly Cell Biology, 4th Edition, provides a concise but comprehensive foundation for students entering research or health care career paths. Award winning illustrations help readers quickly grasp general principles. The authors have thoroughly updated this popular text to provide readers with the current understanding of the principles of normal cellular function along with examples of how molecular defects predispose to human disease. Major new themes in the 4th edition include the roles of intrinsically disordered polypeptides and phase separation in cellular functions, the influence of new molecular structures on understanding mechanisms, and the impact of exciting new methods—from single cell RNA sequencing to second generation super resolution fluorescence microscopy—on advancing our understanding.

    • Clear, readable explanations provide a concise story about how cells function at the molecular level.

    • An intuitive chapter flow starts with genome organization, gene expression, and RNA processing as a foundation for understanding every aspect of cellular function and physiology.

    • Brings cellular biology to life for students interested in medical science by explaining how mutations in genes can compromise virtually every cellular system and predispose to human disease. Knowledge of cell biology has led to new treatments for cancer, heart failure, cystic fibrosis, and many other diseases.

    • Unique illustrations with realistic proportions and relationships explain every cellular process including the assembly of SARS CoV-2, the structures attaching mitotic chromosomes to microtubules, the mechanism of DNA replication and how pumps, carriers and channels orchestrate physiological processes from synaptic transmission to cellular volume regulation.

    • Covers exciting breakthroughs such as SMC motor proteins actively organizing chromosomal DNA, TOR kinases regulating metabolism, new types of immunotherapy for cancer treatment, mechanisms regulating fast axonal transport and their relation to neurodegenerative diseases, how completion of DNA replication sets the time for cells to enter mitosis, how a cascade of signals specifies the site of cell division, and newly understood pathways of normal and pathological cell death.

  • SECTION I
    Introduction to Cell Biology

    1 Cells as the Basis of Life on Earth
    2 Evolution of Life on Earth
    SECTION II
    Chemical and Physical Background

    3 Molecules: Structures and Dynamics
    4 Biophysical Principles
    5 Macromolecular Assembly
    6 Research Strategies
    SECTION III
    Chromatin, Chromosomes, and the Cell Nucleus

    7 Chromosome Organization
    8 DNA Packaging in Chromatin and Chromosomes
    9 Nuclear Structure and Dynamics
    SECTION IV
    Central Dogma: From Gene to Protein

    10 Gene Expression
    11 Eukaryotic RNA Processing
    12 Protein Synthesis and Folding
    SECTION V
    Membrane Structure and Function

    13 Membrane Structure and Dynamics
    14 Membrane Pumps
    15 Membrane Carriers
    16 Membrane Channels
    17 Membrane Physiology
    SECTION VI
    Cellular Organelles and Membrane Trafficking

    18 Posttranslational Targeting of Proteins
    19 Mitochondria, Chloroplasts, Peroxisomes
    20 Endoplasmic Reticulum
    21 Mechanisms of Vesicular Transport
    22 Secretory Membrane System and Golgi Apparatus
    23 Endocytosis and the Endosomal Membrane System
    24 Processing and Degradation of Cellular Components
    SECTION VII
    Signaling Mechanisms

    25 Plasma Membrane Receptors
    26 Protein Hardware for Signaling
    27 Second Messengers
    28 Integration of Signals
    SECTION VIII
    Cellular Adhesion and the Extracellular Matrix

    29 Cells of the Extracellular Matrix and Immune Systems of Animals
    30 Extracellular Matrix Molecules
    31 Cellular Adhesion
    32 Intercellular Junctions
    33 Connective Tissues
    SECTION IX
    Cytoskeleton and Cellular Motility

    34 Actin and Actin-Binding Proteins
    35 Microtubules and Centrosomes
    36 Intermediate Filaments
    37 Motor Proteins
    38 Intracellular Motility
    39 Cellular Motility
    40 Muscles
    SECTION X
    Cell Cycle

    41 Introduction to the Cell Cycle
    42 G1 Phase and Regulation of Cell Proliferation,
    43 S Phase and DNA Replication
    44 G2 Phase: Responses to DNA Damage and Control of Entry Into Mitosis
    45 Mitosis
    46 Cytokinesis
    47 Meiosis
    48 Cell Death
    Cell SnapShots
    Glossary
    Index
  • Thomas D. Pollard, MD, Sterling Professor, Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT, William C. Earnshaw, PhD, FRS, Professor and Wellcome Trust Principal Research Fellow, Wellcome Trust Centre for Cell Biology, ICB, University of Edinburgh, Scotland, United Kingdom, Jennifer Lippincott-Schwartz, PhD, Group Leader, Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, Virginia, United States and Graham Johnson, MA, PhD, CMI, Director, Animated Cell, Allen Institute for Cell Biology, Seattle, Washington;, QB3 Faculty Fellow, University of California, San Francisco, San Francisco, California

$125.99

Or $0.00 with a valid access code