Breast Pathology, 3rd Edition
Brings you fully up to date with recent advances, including new molecular information for breast entities, new surgical techniques, more widely used multigene prognostic tests, and assays used to determine treatment, such as PD-L1 as a new immunotherapy biomarker for triple-negative breast cancer.
Incorporates the latest classifications of breast pathology and molecular diagnosis.
Organizes each topical chapter around relevant genomic and molecular information, clinical presentation, gross and microscopic pathologic findings and diagnostic and molecular immunohistochemistry.
Maps immunohistochemistry for each entity according to diagnostic, theranostic, and genomic applications, with specific regard to disease entities in each chapter.
Discusses breast specimen handling in detail to assure proper sampling and processing for optimal molecular and immunohistochemistry resulting.
Supplies a convenient quick reference at the beginning of each chapter that includes all relevant diagnostic, theranostic, and genomic data for fast retrieval.
Features approximately 2,000 full-color pathological images that clearly depict clinical, radiological, molecular, immunohistochemical, and theranostic aspects of disease.
Includes biomarker guideline updates throughout.
Reflects updates to new tumor staging data in the American Joint Committee on Cancer (AJCC) 8th Edition and updated ASCO/CAP guidelines for interpreting HER2 assays.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
1 Breast Development, Physiology, and Histology
2 Reactive and Inflammatory Conditions of the Breast
3 Infections of the Breast
4 Epidemiology of Breast Cancer and Pathology of Heritable Breast Cancer
5 Patient Safety in Breast Pathology
6 Gross Examination of Breast Specimens
7 Sentinel Lymph Node Biopsy
8 Breast Imaging Modalities for Pathologists
9 Predictive and Prognostic Marker Testing in Breast Pathology: Immunophenotypic Subclasses of Disease
10 Molecular-based Testing in Breast Disease for Therapeutic Decisions
11 Diagnostic Immunohistology of the Breast
12 Fibroepithelial Lesions
13 Papilloma and Papillary Lesions
14 Adenosis and Microglandular Adenosis
15 Nipple Adenoma (Florid Papillomatosis of the Nipple)
16 Radial Scar
17 Myoepithelial Lesions of the Breast
18 Fibrocystic Change and Usual Epithelial Hyperplasia of Ductal Type
19 Columnar Cell Alterations, Flat Epithelial Atypia, and Atypical Ductal Epithelial Hyperplasia
20 Molecular Classification of Breast Carcinoma
21 Lobular Neoplasia and Invasive Lobular Carcinoma
22 Ductal Carcinoma In Situ
23 Invasive Ductal Carcinoma of No Special Type and Histologic Grade
24 Triple-Negative and Basal-like Carcinoma
25 Metaplastic Breast Carcinoma
26 Apocrine Carcinoma of the Breast
27 Paget Disease of the Breast
28 Pathology of Neoadjuvant Therapeutic Response of Breast Carcinoma
29 TOPIC: Special Types of Invasive Breast Carcinoma: Tubular Carcinoma, Mucinous Carcinoma, Cribriform Carcinoma, Micropapillary Carcinoma, Carcinoma With Medullary Features
29 Special Types of Invasive Breast Carcinoma: Tubular Carcinoma, Cribriform Carcinoma, Mucinous Carcinoma, Micropapillary Carcinoma
30 Rare Breast Carcinomas: Adenoid Cystic Carcinoma, Neuroendocrine Carcinoma, Secretory Carcinoma, Carcinoma with Osteoclast-like Giant Cells, Lipid-Rich Carcinoma, and Glycogen-Rich Clear Cell Carcinoma
31 Mesenchymal Neoplasms of the Breast
32 Neoplasia of the Male Breast
33 Breast Tumors in Children and Adolescents
34 Hematopoietic Tumors of the Breast
34 Hematolymphoid Tumors of the Breast
35 Metastatic Tumors in the Breast
36 Next Generation DNA Sequencing and the Management of Patients with Clinically Advanced Breast Cancer
David J Dabbs, MD, Professor of Pathology, University of Hawaii, John A Burns School of Medicine, Honolulu, Hawaii