Addresses hematologic conditions including leukemia, lymphoma, and myeloma
Offers guidance on hematopoietic cell transplantation for solid tumors
Covers basic science principles, clinical aspects, pharmacology, radiation therapy, and disease-specific guidelines, including prevention and management of complications
Discusses key topics such as hematopoietic cell collection, bone marrow harvesting, umbilical cord blood transplantation, CAR T-cell therapy, and patient/donor selection and preparation of HCT
Features extensive summary boxes, bulleted content, and algorithms throughout for quick and easy reference
Offers team-based, clinically-focused coverage from world-renowned leaders in the field
An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud
PART I: Introduction and Biological Aspects 1. Hematopoietic Transplantation: Past, Present, and Future 2. Role of the Human Leukocyte Antigen System in Hematopoietic Stem Cell Transplantation
PART II: Methodology 3. Hematopoietic Cell Collection 4. Bayesian Statistical Methods in Stem Cell Transplantation and Cellular Therapy
PART III: General Clinical Aspects 5. Patient and Donor Assessments in Preparation for Transplant 6. Transfusion Support During Hematopoietic Cell Transplantation 7. Haploidentical Hematopoietic Cell Transplantation 8. Umbilical Cord Blood Transplantation 9. Process and General Management of Patients Undergoing Chimeric Antigen Receptor Therapies
PART IV: Pharmacology and Radiation Therapy 10. Preparative Regimens Used in Hematopoietic Cell Transplantation and Chimeric Antigen Receptor T-Cell Therapies 11. Pharmacology of Drugs Used in Hematopoietic Cell Transplant and Chimeric Antigen Receptor Therapies 12. Radiobiologic Principles and the Role of Radiotherapy in Hematopoietic Cell Transplant and Chimeric Antigen Receptor T-Cell Therapy
PART V: Disease-Specific Indications and Results 13. Hematopoietic Cell Transplantation in Adult With Acute Myeloid Leukemia 14. Chimeric Antigen Receptor Therapy in Acute Myeloid Leukemia 15. Allogeneic Hematopoietic Cell Transplantation for Patients With Acute Lymphoblastic Leukemia 16. Chimeric Antigen Receptor T-Cell Therapy in Acute Lymphoblastic Leukemia 17. Hematopoietic Cell Transplantation and Other Cellular Therapies for Chronic Lymphocytic Leukemia 18. Allogeneic Hematopoietic Cell Transplantation in Myelodysplastic Syndrome Patients 19. Allogeneic Cell Transplantation for Myeloproliferative Neoplasms 20. Hematopoietic Cell Transplantation in Aplastic Anemia 21. Hematopoietic Cell Transplantation in Multiple Myeloma 22. Chimeric Antigen Receptor Therapy in Multiple Myeloma 23. Hematopoietic Cell Transplantation in Light Chain Amyloidosis 24. Hematopoietic Cell Transplantation for Non-Hodgkin Lymphoma 25. Hematopoietic Cell Transplantation for Hodgkin Lymphoma 26. Chimeric Antigen Receptor Therapy in Lymphoma 27. Hematopoietic Cell Transplantation in Rare Hematologic Malignancies 28. Hematopoietic Cell Transplantation for Germ-Cell Tumors and Other Adult Solid Tumors 29. Natural Killer Cells: A Promising Cellular Therapy Platform to Conquer Cancer
PART VI: Prevention and Management of Complications 30. Infection Control, Prophylaxis, and Vaccinations in Hematopoietic Cell Transplantation Recipients 31. Management of Infections in Stem Cell Transplant Recipients 32. Graft Failure After Hematopoietic Cell Transplantation 33. Graft-Versus-Host Disease 34. Miscellaneous Complications of Hematopoietic Cellular Transplantation 35. Cytokine Release Syndrome Following CD19 Directed Chimeric Antigen Receptor T-Cell Therapy 36. Neurologic Complications of Chimeric Antigen Receptor Therapy 37. Miscellaneous Complications of Chimeric Antigen Receptor T-Cell Therapy 38. Symptom Management and Palliative Care in Hematologic Malignancies 39. Survivorship
Qaiser Bashir, MD, Associate Professor of Medicine, Department of Stem Cell Transplantation & Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, Texas, USA, Elizabeth J. Shpall, MD, Professor and Chair, at interim, Department of Stem Cell Transplantation and Cellular Therapy, Division of Cancer MedicineDirector, Cell Therapy Laboratory, Director, Cord Blood Bank, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA and Richard E. Champlin, MD, Professor, Department of Stem Cell Transplantation and Cellular Therapy, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
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