Hematopathology, 3rd Edition
Hardcover
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- Helps you navigate the latest changes in the classification of hematolymphoid neoplasms, providing guidance for use of both the International Consensus Classification (ICC) and 5th edition of the WHO classification.
- Incorporates the latest molecular/cytogenetic information, regarding newly recognized entities and the latest diagnostic criteria.
- Provides you with today's most effective guidance in evaluating specimens from the lymph nodes, bone marrow, peripheral blood, and more, with authoritative information on the pathogenesis, clinical and pathologic diagnosis, and treatment for each.
- Details the latest insights on the molecular biology of benign and malignant hematologic disorders.
- Features more than 1,100 high-quality color images that mirror the findings you encounter in practice.
- Uses an easy-to-navigate, templated format with standard headings in each chapter.
- Includes information on disease progression and prognosis, helping you better understand the clinical implications of diagnosis.
- Shares the knowledge and expertise of new editors, Drs. Lisa Rimsza, Attilio Orazi, and Steven Swerdlow, providing expertise in molecular diagnostics, bone marrow and lymph node biopsies.
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.
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PART I Technical Aspects 1 Processing of the Lymph Node Biopsy Specimen 2 Fine-Needle Aspiration of Lymph Nodes 3 Immunohistochemistry for the Hematopathology Laboratory 4 Flow Cytometry 5 Molecular Pathology of Hematologic Neoplasms 6 Important Chromosomal Aberrations in Hematologic Neoplasms and Key Techniques to Diagnose Them PART II Normal and Reactive Conditions of Hematopoietic Tissues 7 Normal Lymphoid Organs and Tissues 8 Reactive Lymphadenopathies 9 The Normal Bone Marrow 10 Evaluation of Anemia, Leukopenia, and Thrombocytopenia 11 Bone Marrow Findings in Inflammatory, Infectious, and Metabolic Disorders PART III Lymphoid Neoplasms 12 Principles of Classification of Lymphoid Neoplasms SECTION 1 • MATURE B-CELL NEOPLASMS 13 Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Monoclonal B-Cell Lymphocytosis, and B-Cell Prolymphocytic Leukemia 14 Lymphoplasmacytic Lymphoma and Waldenström Macroglobulinemia 15 Hairy Cell Leukemia 16 Splenic Marginal Zone Lymphoma and Other Small B-Cell Neoplasms in the Spleen 17 Follicular Lymphoma 18 Extranodal Marginal Zone Lymphoma: MALT Lymphoma 19 Primary Cutaneous B-Cell Lymphomas 20 Nodal Marginal Zone Lymphoma 21 Mantle Cell Lymphoma 22 Aggressive B-Cell Lymphomas Including Diffuse Large B-Cell Lymphoma, Not Otherwise Specified and Other Nodal and Extranodal Large B-Cell Lymphomas 23 Burkitt Lymphoma, High-Grade B-Cell Lymphoma Not Otherwise Specified, High-Grade B-Cell Lymphoma With MYC and BCL2/BCL6 Rearrangements, Large B-Cell Lymphoma With 11q Aberration, and Provisional Entity High-Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements 24 Plasmablastic Neoplasms Other Than Plasma Cell Myeloma 25 Plasma Cell Neoplasms 26 Nodular Lymphocyte-Predominant B-Cell Lymphoma 27 Classic Hodgkin Lymphoma 28 Virally Associated B-Cell Lymphoproliferative Disease SECTION 2 • MATURE T-CELL AND NK-CELL NEOPLASMS 29 Epstein-Barr Virus–Associated T-Cell and Natural Killer–Cell Lymphoproliferative Disorders 30 T-Cell and NK-Cell Large Granular Lymphocyte Proliferations 31 T-Cell Prolymphocytic Leukemia 32 Adult T-Cell Leukemia/Lymphoma 33 Hepatosplenic T-Cell Lymphoma 34 Peripheral T-Cell Lymphoma, Not Otherwise Specified 35 Follicular Helper T-Cell Lymphoma 36 Anaplastic Large Cell Lymphoma, ALK Positive and ALK Negative 37 Enteropathy-Associated T-Cell Lymphoma and Other Primary Intestinal T-Cell Lymphomas 38 Mycosis Fungoides and Sézary Syndrome 39 Primary Cutaneous CD30-Positive T-Cell Lymphoproliferative Disorders 40 Primary Cutaneous T-Cell Lymphomas: Rare Subtypes SECTION 3 • PRECURSOR B- AND T-CELL NEOPLASMS 41 Precursor B-Cell and T-Cell Neoplasms 42 Acute Leukemias of Ambiguous Lineage PART IV Myeloid, Histiocytic, and Related Proliferations 43 Principles of Classification of Myeloid Neoplasms 44 The Myelodysplastic Syndromes 45 Myeloid and Hematologic Neoplasms With Germline Predisposition 46 Acute Myeloid Leukemia 47 Myeloproliferative Neoplasms 48 Myelodysplastic/Myeloproliferative Neoplasms and Premalignant Conditions 49 Mastocytosis 50 Eosinophilia, Chronic Eosinophilic Leukemia, Not Otherwise Specified, and Myeloid/Lymphoid Neoplasms With Eosinophilia and Tyrosine Kinase Gene Fusions 51 Blastic Plasmacytoid Dendritic Cell Neoplasm 52 Histiocytic and Dendritic Cell Proliferations—Systemic and Neoplastic PART V Immunodeficiency Disorders 53 The Pathology of Primary Immunodeficiencies 54 Iatrogenic Immunodeficiency-Associated Lymphoproliferative Disorders PART VI Site-Specific Issues in the Diagnosis of Lymphoma and Leukemia 55 Bone Marrow Evaluation for Lymphoma 56 Evaluation of the Bone Marrow After Therapy 57 Non-hematopoietic Neoplasms and Other Lesions of the Bone Marrow and Lymph Nodes 58 Spleen: Normal Architecture and Neoplastic and Non-neoplastic Lesions 59 Diagnosis of Lymphoma in Extranodal Sites Other Than Skin APPENDIX A: THE INTERNATIONAL CONSENSUS CLASSIFICATION OF MYELOID, LYMPHOID, AND HISTIOCYTIC NEOPLASMS INDEX