Bland and Copeland's The Breast, 6th Edition

SECTION I History of the Therapy of Breast Cancer
1. The History of the Therapy for Breast Cancer
2. History of Surgical Clinical Trials and Cooperative Group Trials
3. Important Trials of the Last Decade

SECTION II Anatomy and Physiology of the Normal and Lactating Breast
4. Anatomy of the Breast, Axilla, Chest Wall, and Related Metastatic Sites
5. Breast Physiology: Normal and Abnormal Development and Function
6. Discharges and Secretions of the Nipple

SECTION III Natural History, Epidemiology, Genetics, and Syndromes of the Breast
7. Epidemiology of Breast Cancer
8. Carcinogenesis of Breast Cancer
9. Risk Reduction for Developing Breast Cancer
10. Breast Cancer Genetics: Syndromes, Genes, Pathology, Counseling, Testing, and Treatment

SECTION IV Screening and Diagnosis of the Breast Patient
11. Clinical Encounter With the Patient
12. Breast Cancer Screening
13. Breast Cancer Diagnosis and Techniques for Biopsy

SECTION V Benign and Premalignant Lesions
14. Etiology and Management of Benign Breast Disease
15. Mastitis and Breast Abscess
16. Gynecomastia
17. High-Risk and Premalignant Lesions of the Breast

SECTION VI Pathology of Malignant Lesions
18. Disorders of the Skin
19. Ductal Carcinoma In Situ
20. Infiltrating Carcinomas of the Breast
21. Biomarkers
22. Fibroepithelial Tumors and Hamartomas
23. Lymphomas of the Breast
24. Mesenchymal Neoplasms of the Breast
25. Unusual and Rare Tumors of the Breast

SECTION VII Prognostic Factors for Breast Cancer
26. Clinical Prognosis and Staging of Breast Cancer
27. Molecular Biomarkers for Breast Cancer Prognosis
28. Examining Domestic and International Disparities in Breast Cancer Screening, Treatment, and Outcomes

SECTION VIII Surgical Techniques of the Breast
29. Management of Lobular Neoplasia and Ductal Carcinoma In Situ
30. General Principles of Mastectomy: From Halsted Radical Mastectomy and Modified Radical Mastectomy to Total (Simple) Mastectomy
31. Breast Conservation Therapy for Invasive Breast Cancer
32. Intraoperative Evaluation of Surgical Margins in Breast-Conserving Therapy
33. Lymphatic Mapping and Sentinel Lymphadenectomy for Breast Cancer
34. Lymphatic Mapping and Targeted Axillary Dissection Procedure After Neoadjuvant Chemotherapy
35. Therapeutic Value of Axillary Node Dissection
36. Lymphedema Prevention and Treatment: Axillary Reverse Mapping, LYMPHA, Lymph Node Transfer, and Other Surgical Techniques
37. Wound Care and Complications of Mastectomy
38. Pain Management of the Breast Cancer Surgery Patient

SECTION IX Oncoplastic Breast Surgery and Reconstruction
39. Optimizing Cosmetic Outcomes for Breast Surgery
40. Upper Hemisphere Oncoplastic Surgery
41. Oncoplastic Techniques for the Lower Hemisphere of the Breast
42. Oncoplastic Breast Reconstruction: Extreme Oncoplasty and Split Reduction Techniques
43. Nipple Skin-Sparing Mastectomy
44. Breast Reconstruction

SECTION X Adjuvant Therapy for Stages 0, I, and II Breast Cancer
45. Radiotherapy and Regional Nodes
46. Postmastectomy Radiation Therapy
47. Breast-Conserving Therapy for Invasive Breast Cancers
48. Partial Breast Irradiation: Accelerated and Intraoperative
49. Radiation Complications and Their Management
50. Radiation Therapy for Locally Advanced Breast Cancer: Historical Review to Current Approaches
51. Systemic Therapy of Hormone-Sensitive HER2-Negative Breast Cancer: Adjuvant and Neoadjuvant
52. Adjuvant and Neoadjuvant Systemic Therapies for Triple-Negative Breast Cancer
53. Adjuvant and Neoadjuvant HER2 Therapy

SECTION XI Management of Advanced Local, Regional, and Systemic Disease
54. Surgical Procedures for Advanced Local and Regional Malignancies of the Breast
55. Management of the Intact Breast Primary in the Setting of Metastatic Disease
56. Locoregional Recurrence of Breast Cancer
57. Locally Advanced and Inflammatory Breast Cancer
58. Clinical Implications of Occult Systemic Micrometastatic Breast Cancer
59. Management of Breast Cancer Solitary Metastases
60. Management of Bone Metastases in Breast Cancer
61. Chemotherapy and HER2-Directed Therapy for Metastatic Breast Cancer
62. Endocrine Therapy for Late-Stage and Metastatic Breast Cancer
63. Immunological Approaches to Breast Cancer Therapy
64. Diagnosis and Management of Pleural Metastases and Malignant Effusion in Breast Cancer
65. Management of Central Nervous System Metastases in Breast Cancer

SECTION XII Special Presentations of Breast Cancer
66. Bilateral Breast Cancer
67. Male Breast Cancer
68. Local Recurrence, the Augmented Breast, and the Contralateral Breast
69. Carcinoma of the Breast in Pregnancy and Lactation
70. Unknown Primary Presenting With Axillary Lymphadenopathy

SECTION XIII Survivorship, Follow-Up Care, and Rehabilitation of the Breast Cancer Patient
71. Creating a Breast Cancer Survivorship Plan and Clinic
72. General Considerations for Follow-Up
73. Bone-Modifying Agents in Early Breast Cancer
74. Fertility Preservation for Women With Breast Cancer
75. Quality Measures and Performance Improvement for Breast Cancer Surgery
76. Lymphedema in the Postsurgical Patient: Pathophysiology and Nonoperative Management
77. Management of Menopause in Breast Cancer Survivors
78. Rehabilitation
79. Psychosocial Consequences and Lifestyle Interventions

Kirby I. Bland, MD, Professor and Chairman, Department of Surgery; Deputy Director, UAB Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, USA, Edward M. Copeland, MD, Emeritus Distinguished Professor, Chairman, Department of Surgery; Director of the Shands Cancer Center, Department of Surgery, University of Florida College of Medicine, Gainsville, Florida, USA, V. Suzanne Klimberg, MD, PhD, The Courtney M. Townsend, Jr., M.D. Distinguished Chair in General Surgery, Vice Chair for Administration, Professor of Surgery, University of Texas Medical Branch, Galveston, Texas, USA and William J. Gradishar, MD, Betsy Bramsen Professor of Breast Oncology, Professor, Department of Medicine-Hematology/Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA