The Netter Collection of Medical Illustrations: Musculoskeletal System, Volume 6, Part III - Biology and Systemic Diseases, 3rd Edition

• Provides a highly visual guide to embryology and physiology, metabolic disorders, congenital and development disorders, rheumatic diseases, tumors of the musculoskeletal system, injury to the musculoskeletal system, soft tissue infections, and fracture complications.
• Provides a concise overview of complex information by seamlessly integrating anatomical and physiological concepts using practical clinical scenarios.
• Shares the experience and knowledge of Drs. Joseph P. Iannotti, Richard D. Parker, Abby G. Abelson, and Brendan M. Patterson, and esteemed colleagues from the Cleveland Clinic, who clarify and expand on the illustrated concepts.
• Compiles Dr. Frank H. Netter’s master medical artistry—an aesthetic tribute and source of inspiration for medical professionals for over half a century—along with new art in the Netter tradition for each of the major body systems, making this volume a powerful and memorable tool for building foundational knowledge and educating patients or staff.
• NEW! An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, make notes and highlights, and have content read aloud.

SECTION 1 EMBRYOLOGY 1.1 Amphioxus and Human Embryo at 16 Days 1.2 Differentiation of Somites into Myotomes, Sclerotomes, and Dermatomes 1.3 Progressive Stages in Formation of Vertebral Column, Dermatomes, and Myotomes; Mesenchymal Precartilage Primordia of Axial and Appendicular Skeletons at 5 Weeks 1.4 Fate of Body, Costal Process, and Neural Arch Components of Vertebral Column, with Sites and Time of Appearance of Ossification Centers 1.5 First and Second Cervical Vertebrae at Birth; Development of Sternum 1.6 Early Development of Skull 1.7 Skeleton of Full-Term Newborn 1.8 Changes in Position of Limbs Before Birth; Precartilage Mesenchymal Cell Concentrations of Appendicular Skeleton at 6 Weeks 1.9 Changes in Ventral Dermatome Pattern During Limb Development 1.10 Initial Bone Formation in Mesenchyme; Early Stages of Flat Bone Formation 1.11 Secondary Osteon (Haversian System) 1.12 Growth and Ossification of Long Bones 1.13 Growth in Width of a Bone and Osteon Remodeling 1.14 Remodeling: Maintenance of Basic Form and Proportions of Bone during Growth 1.15 Development of Three Types of Synovial Joints 1.16 Segmental Distribution of Myotomes in Fetus of 6 Weeks; Developing Skeletal Muscles at 8 Weeks 1.17 Development of Skeletal Muscle Fibers 1.18 Cross Sections of Body at 6 to 7 Weeks 1.19 Prenatal Development of Perineal Musculature 1.20 Origins and Innervations of Pharyngeal Arch and Somite Myotome Muscles 1.21 Branchiomeric and Adjacent Myotomic Muscles at Birth SECTION 2 PHYSIOLOGY 2.1 Microscopic Appearance of Skeletal Muscle Fibers 2.2 Organization of Skeletal Muscle 2.3 Intrinsic Blood and Nerve Supply of Skeletal Muscle 2.4 Composition and Structure of Myofilaments 2.5 Muscle Contraction and Relaxation 2.6 Biochemical Mechanics of Muscle Contraction 2.7 Sarcoplasmic Reticulum and Initiation of Muscle Contraction 2.8 Initiation of Muscle Contraction by Electric Impulse and Calcium Movement 2.9 Motor Unit 2.10 Structure of Neuromuscular Junction 2.11 Physiology of Neuromuscular Junction 2.12 Pharmacology of Neuromuscular Transmission 2.13 Physiology of Muscle Contraction 2.14 Energy Metabolism of Muscle 2.15 Muscle Fiber Types 2.16 Growth Plate: Structure, Physiology, and Pathophysiology 2.17 Growth Plate: Structure, Physiology, and Pathophysiology (Continued) 2.18 Growth Plate: Structure and Blood Supply 2.19 Growth Plate: Peripheral Fibrocartilaginous Element 2.20 Composition and Structure of Cartilage 2.21 Bone Cells and Bone Deposition 2.22 Composition of Bone 2.23 Structure of Cortical (Compact) Bone 2.24 Structure of Trabecular Bone 2.25 Formation and Composition of Collagen 2.26 Formation and Composition of Proteoglycan 2.27 Structure and Function of Synovial Membrane 2.28 Histology of Connective Tissue 2.29 Bone Homeostasis: Dynamics 2.30 Bone Homeostasis: Regulation of Calcium and Phosphate Metabolism 2.31 Effects of Bone Formation and Bone Resorption on Skeletal Mass 2.32 Four Mechanisms of Bone Mass Regulation 2.33 Normal Calcium and Phosphate Metabolism 2.34 Nutritional Calcium Deficiency 2.35 Effects of Disuse and Stress (Weight Bearing) on Bone Mass 2.36 Musculoskeletal Effects of Weightlessness (Space Flight) 2.37 Bone Architecture and Remodeling in Relation to Stress 2.38 Stress-Generated Electric Potentials in Bone 2.39 Bioelectric Potentials in Bone 2.40 Age-Related Changes in Bone Geometry 2.41 Age-Related Changes in Bone Geometry (Continued) SECTION 3 METABOLIC DISEASES 3.1 Parathyroid Hormone 3.2 Primary Hyperparathyroidism: Pathophysiology 3.3 Primary Hyperparathyroidism: Clinical Manifestations 3.4 Differential Diagnosis of Hypercalcemic States 3.5 Hypoparathyroidism: Pathologic Physiology 3.6 Chronic Hypoparathyroidism: Clinical Manifestations 3.7 Hypocalcemia: Clinical Manifestations 3.8 Pseudohypoparathyroidism 3.9 Mechanism of Parathyroid Hormone Activity on End Organ 3.10 Mechanism of Parathyroid Hormone Activity on End Organ: Cyclic AMP Response to PTH 3.11 Clinical Guide to Parathyroid Hormone Assay 3.12 Clinical Guide to Parathyroid Hormone Assay (Continued) 3.13 Childhood Rickets 3.14 Adult Osteomalacia 3.15 Nutritional Deficiency: Rickets and Osteomalacia 3.16 Vitamin D–Resistant Rickets and Osteomalacia Due to Proximal Renal Tubular Defects (Hypophosphatemic Rachitic Syndromes) 3.17 Vitamin D–Resistant Rickets and Osteomalacia Due to Proximal and Distal Renal Tubular Defects 3.18 Vitamin D–Dependent (Pseudodeficiency) Rickets and Osteomalacia 3.19 Vitamin D–Resistant Rickets and Osteomalacia Due to Renal Tubular Acidosis 3.20 Metabolic Aberrations of Renal Osteodystrophy 3.21 Rickets, Osteomalacia, and Renal Osteodystrophy 3.22 Bony Manifestations of Renal Osteodystrophy 3.23 Vascular and Soft Tissue Calcification in Secondary Hyperparathyroidism of Chronic Renal Disease 3.24 Clinical Guide to Vitamin D Measurement 3.25 Hypophosphatasia 3.26 Osteoporosis: Risk Factors 3.27 Osteoporosis: Involutional 3.28 Osteoporosis: Clinical Manifestations 3.29 Osteoporosis: Progressive Spinal Deformity 3.30 Radiology of Osteopenia: Classification 3.31 Radiology of Osteopenia: Imaging 3.32 Radiology of Osteopenia: DXA 3.33 Transiliac Bone Biopsy 3.34 Treatment of Complications of Spinal Osteoporosis 3.35 Treatment of Osteoporosis: Medications 3.36 Treatment of Osteoporosis: Functional Domains of Bisphosphonate Chemical Structure 3.37 Treatment of Osteoporosis: Inhibition of FPP Synthase 3.38 Osteogenesis Imperfecta Type I 3.39 Osteogenesis Imperfecta Type III 3.40 Marfan Syndrome 3.41 Marfan Syndrome (Continued) 3.42 Ehlers-Danlos Syndromes 3.43 Ehlers-Danlos Syndromes (Continued) 3.44 Osteopetrosis (Albers-Schönberg Disease) 3.45 Paget Disease of Bone 3.46 Paget Disease of Bone (Continued) 3.47 Pathophysiology and Treatment of Paget Disease of Bone 3.48 Fibrodysplasia Ossificans Progressiva SECTION 4 CONGENITAL AND DEVELOPMENTAL DISORDERS Dwarfism 4.1 Achondroplasia: Clinical Manifestations 4.2 Achondroplasia: Clinical Manifestations (Continued) 4.3 Achondroplasia: Clinical Manifestations of Spine 4.4 Achondroplasia: Diagnostic Testing 4.5 Hypochondroplasia 4.6 Diastrophic Dwarfism 4.7 Pseudoachondroplasia 4.8 Metaphyseal Chondrodysplasia, McKusick Type 4.9 Metaphyseal Chondrodysplasia, Schmid Type 4.10 Chondrodysplasia Punctata 4.11 Chondroectodermal Dysplasia (Ellis-van Creveld Syndrome), Grebe Chondrodysplasia, and Acromesomelic Dysplasia 4.12 Multiple Epiphyseal Dysplasia, Fairbank Type 4.13 Pycn