McAlpine's Multiple Sclerosis, 5th Edition

by Alasdair Coles, PhD, V. Wee Yong, Alastair Compston, PhD, MBBS, FRCP, Ruth Dobson, Benjamin M. Jacobs, PhD BM BCh (Oxon), Hans Lassmann, Catherine Lubetzki, Maria A. Rocca, Steve Vucic and Brian Weinshenker

Hardcover

ISBN: 9780323936347

Page Count: 1000

Imprint: Elsevier

List Price: $262.99

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For more than 70 years, McAlpine's Multiple Sclerosis has been the gold standard textbook on the science and clinical practice of MS. The 5th Edition of this classic, landmark text reflects recent advances in this complex field, bringing you up to date with current information on genetics, epidemiology, clinical neurology, pathogenesis, and management of this common neurological disease. Easy to read and abundantly illustrated, this updated reference is a must-have resource for neurologists, neuropathologists, neurophysiologists, researchers, PM&R specialists, and others who can benefit from authoritative, comprehensive coverage of both scientific and clinical aspects of MS.

Key Features
- Discusses recent advances in both diagnosis and management, including improved understanding of MS in childhood and the elderly, anti-MOG disease, treatments of progressive MS, remyelination and neuroprotective therapies, and more
- Offers authoritative reviews of the current literature, placed in historical context
- Features more than 550 high-quality illustrations clarifying important scientific and clinical concepts
- Provides the most authoritative and comprehensive history of the understanding of the disease
- Uses a remarkably clear presentation to make complicated data easier to understand
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date
Contents

SECTION 1: Story and Iconography of Multiple Sclerosis
1. The Concept of Multiple Sclerosis
2. The Pathogenesis and Etiology of Multiple Sclerosis
3. The Person With Multiple Sclerosis: Treatment and Society
4. Telling the Story: Literature and McAlpine’s Multiple Sclerosis

SECTION 2: The Course and Cost of Multiple Sclerosis
5. Distribution of Multiple Sclerosis
6. Natural History of Multiple Sclerosis

SECTION 3: Recognizing and Diagnosing Multiple Sclerosis
7. Diagnosis and Classification of Multiple Sclerosis
8. Symptoms and Signs
9. Imaging Structure
10. Measuring Function
11. Blood and CSF Markers of Damage and Disease Activity
12. Diagnosis and Differential Diagnosis

SECTION 4: The Cause and Pathogenesis of Multiple Sclerosis
13. Genetic Analysis of Multiple Sclerosis
14. Immunology of Multiple Sclerosis
15. Neurobiology of Multiple Sclerosis
16. The Pathogenesis of Multiple Sclerosis: A Pandect

SECTION 5: Treating the Person With Multiple Sclerosis
17. Care of the Person With Multiple Sclerosis
18. The Acute Attack of Multiple Sclerosis and Its Treatment
19. The Treatment of Symptoms in Multiple Sclerosis
20. Disease-Modifying Immunotherapies
21. Reparative Therapies
22. Monitoring Treatment
Authors

Alasdair Coles, PhD, Professor, Neuroimmunology, University of Cambridge, Cambridge UK, V. Wee Yong, Professor of Translational Neuroscience, Hotchkiss Brain Institute and the Departments of Clinical Neurosciences and Oncology at The University of Calgary, Canada, Alastair Compston, PhD, MBBS, FRCP, Professor of Neurology, University of Cambridge, Cambridge, UK, Ruth Dobson, MBBS, PhD, Benjamin M. Jacobs, PhD BM BCh (Oxon), Hans Lassmann, Catherine Lubetzki, Professor of Neurology, Pierre and Marie Curie University, head, Department of Neurological Diseases, Salpêtrière Hospital, France, Maria A. Rocca, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Italy, Steve Vucic and Brian Weinshenker, Professor of Neurology, University of Virginia, USA