ISBN:
9780323936811
Copyright:
2026
Publication Date:
01-24-2025
Page Count:
936
Imprint:
Elsevier
List Price:
$121.99
Lehne’s Pharmacotherapeutics for Advanced Practice Nurses and Physician Assistants - Elsevier EBook on VitalSource (Retail Access Card), 3rd Edition
by Laura D. Rosenthal, DNP, RN, ACNP-BC, FAANP and Jacqueline Rosenjack Burchum, DNSc, FNP-BC, CNE
Elsevier eBook on VitalSource - Access Card
ISBN:
9780323936811
Copyright:
2026
Publication Date:
01-24-2025
Page Count:
936
Imprint:
Elsevier
List Price:
$121.99
Was
$121.99
Now $113.45
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Lehne's Pharmacotherapeutics for Advanced Practice Nurses and Physician Assistants, Third Edition builds on the same foundation of clearly explained, up-to-date, and clinically current content as Lehne’s trusted undergraduate text, while focusing on the information that advanced practice nurses and Physician Assistants specifically need for safe and effective prescribing. Introductory chapters provide foundational content in the areas of prescriptive authority, rational drug selection, prescription writing, and promoting positive outcomes of drug therapy. Core drug chapters focus on the drugs that you will most commonly see in clinical practice. Pharmacotherapeutic decision-making is emphasized, with Black Box Warnings and new Drug Decision Guide boxes. This edition features completely updated content with new chapters on drugs for sexual dysfunction and drugs for transgender health. It’s everything you need to be a safe and effective prescriber!
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- UPDATED! Content throughout reflects the latest drug information and evidence-based treatment guidelines and protocols
- NEW! Drugs for Sexual Dysfunction and Drugs for Transgender Health chapters in a newly combined Reproductive Health unit promote health equity
- NEW! Drug Decision Guide boxes for selected drugs emphasize a rational process for drug selection
- NEW! Clinical Pearls boxes highlight expert tips for rational drug prescription
- NEW! Chapter-opening Evolve links and “Top 300” drug icons throughout identify drugs that appear on the Top 300 prescribed drug list to help you focus your study time
- ENHANCED! Introductory chapters emphasize prescriber-level pharmacokinetics and pharmacodynamics content
- NEW! Coverage addresses immunizations and therapeutics (e.g., Regeneron, Resdemivir, dexamethasone) for SARS-CoV-2 infection (COVID-19)
- UPDATED! Enhanced coverage of sexually transmitted infections reflects the latest evidence-based guidelines
- NEW! Drug content addresses medications for ectoparasite infestations
- Introductory chapters tailored to the specific needs of beginning prescribers cover topics such as prescriptive authority, rational drug selection and prescription writing, and promoting positive outcomes of drug therapy
- Carefully focused pharmacotherapeutics content reflects the drugs most commonly seen and used by primary and acute care prescribers, with an emphasis not on the first drug discovered or developed in each drug class, but on the agents most often used today
- Chapters address primary care drugs first, as appropriate, followed by acute care drugs
- Prescriber-focused pedagogical aids further reinforce the most important information for prescribers
- UNIQUE! Summary of Key Prescribing Considerations at the end of each drug chapter provides a concise summary of essential prescriber information
- Coverage of interprofessional collaboration addresses the growing global emphasis on interprofessional collaboration and incorporates opportunities for interprofessional collaborative practice throughout
- Integrated coverage of Canadian trade names appears throughout and is highlighted with a familiar maple-leaf icon
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UNIT I Introduction
1. Prescriptive Authority
2. Rational Drug Selection and Prescription Writing
3. Promoting Positive Outcomes of Drug Therapy
UNIT II Basic Principles of Pharmacology
4. Pharmacokinetics, Pharmacodynamics, and Drug Interactions
5. Adverse Drug Reactions and Medication Errors
6. Individual Variation in Drug Responses
7. Genetic and Genomic Considerations in Pharmacotherapeutics
UNIT III Drug Therapy Across the Life Span
8. Drug Therapy During Pregnancy and Breastfeeding
9. Drug Therapy in Pediatric Patients
10. Drug Therapy in Geriatric Patients
UNIT IV Peripheral Nervous System Drugs
11. Basic Principles of Neuropharmacology
12. Physiology of the Peripheral Nervous System
13. Muscarinic Agonists and Cholinesterase Inhibitors
14. Muscarinic Antagonists
15. Adrenergic Agonists
16. Adrenergic Antagonists
17. Indirect-Acting Antiadrenergic Agents
UNIT V Central Nervous System Drugs
18. Introduction to Central Nervous System Pharmacology
19. Drugs for Parkinson Disease
20. Drugs for Alzheimer Disease
21. Drugs for Seizure Disorders
22. Drugs for Muscle Spasm and Spasticity
UNIT VI Drugs for Pain
23. Local Anesthetics
24. Opioid Analgesics, Opioid Antagonists, and Nonopioid Centrally Acting Analgesics
25. Drugs for Headache
UNIT VII Psychotherapeutic Drugs
26. Antipsychotic Agents and Their Use in Schizophrenia
27. Antidepressants
28. Drugs for Bipolar Disorder
29. Sedative-Hypnotic Drugs
30. Management of Anxiety Disorders
31. Central Nervous System Stimulants and Attention-Deficit/Hyperactivity Disorder
UNIT VIII Substance Use Disorders
32. Substance Use Disorders I: Basic Considerations
33. Substance Use Disorders II: Alcohol
34. Substance Use Disorders III: Nicotine and Smoking
35. Substance Use Disorders IV: Major Drugs of Misuse Other Than Alcohol and Nicotine
UNIT IX Drugs That Affect the Heart, Blood Vessels, Blood, and Blood Volume
36. Review of Hemodynamics
37. Diuretics
38. Drugs Acting on the Renin-Angiotensin-Aldosterone System
39. Calcium Channel Blockers
40. Vasodilators
41. Drugs for Hypertension
42. Drugs for Heart Failure
43. Antidysrhythmic Drugs
44. Prophylaxis of Atherosclerotic Cardiovascular Disease: Drugs That Help Normalize Cholesterol and Triglyceride Levels
45. Drugs for Angina Pectoris
46. Anticoagulant and Antiplatelet Drugs
47. Drugs for Deficiency Anemias
UNIT X Drugs for Endocrine Disorders
48. Drugs for Diabetes
49. Drugs for Thyroid Disorders
UNIT XI Reproductive Health
50. Estrogens and Progestins: Basic Pharmacology and Noncontraceptive Applications
51. Birth Control
52. Androgens
53. Drugs for Benign Prostatic Hyperplasia
54. Drugs for Sexual Dysfunction
55. Transgender Health
UNIT XII Antiinflammatory, Antiallergic, and Immunologic Drugs
56. Review of the Immune System
57. Childhood Immunization
58. Antihistamines
59. Cyclooxygenase Inhibitors, Nonsteroidal Antiinflammatory Drugs, and Acetaminophen
60. Glucocorticoids in Nonendocrine Disorders
UNIT XIII Drugs for Bone and Joint Disorders
61. Drug Therapy for Rheumatoid Arthritis
62. Drug Therapy for Gout
63. Drugs Affecting Calcium Levels and Bone Mineralization
UNIT XIV Respiratory Tract Drugs
64. Drugs for Asthma and Chronic Obstructive Pulmonary Disease
65. Drugs for Allergic Rhinitis, Cough, and Colds
UNIT XV Gastrointestinal Drugs
66. Drugs for Peptic Ulcer Disease
67. Laxatives
68. Other Gastrointestinal Drugs
UNIT XVI Nutrition and Complementary Therapies
69. Vitamins
70. Drugs for Obesity
71. Complementary and Alternative Therapy
UNIT XVII Therapy for Infectious and Parasitic Diseases
72. Basic Principles of Antimicrobial Therapy
73. Drugs That Weaken the Bacterial Cell Wall I: Penicillins
74. Drugs That Weaken the Bacterial Cell Wall II: Other Drugs
75. Bacteriostatic Inhibitors of Protein Synthesis
76. Aminoglycosides: Bactericidal Inhibitors of Protein Synthesis
77. Sulfonamide Antibiotics and Trimethoprim
78. Drug Therapy for Urinary Tract Infections
79. Drug Therapy for Tuberculosis
80. Miscellaneous Antibacterial Drugs
81. Antifungal Agents
82. Antiviral Agents I: Drugs for Non-HIV Viral Infections
83. Antiviral Agents II: Drugs for HIV Infection
84. Drug Therapy for Sexually Transmitted Infections
85. Anthelmintics
UNIT XVIII Cancer Therapy
86. Introduction to Immunomodulators
87. Supportive Care of Patients Receiving Anticancer Drugs
88. Drugs for Cancer Pain
UNIT XIX Drugs for Eyes, Ears, and Skin
89. Drugs for Disorders of the Eye
90. Drugs for Disorders of the Skin
91. Drugs for Disorders of the Ear
UNIT XX Drug Therapy in Acute Care
92. Agents Affecting the Volume and Ion Content of Body Fluids
93. Management of ST-Elevation Myocardial Infarction
94. Drugs for Acute Care
Appendix: Canadian Drug Information
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