cover image - Sleisenger and Fordtran's Gastrointestinal and Liver Disease - 2 Volume Set, 12th Edition
ISBN: 9780443116575
Copyright: 2026
Publication Date: 12-10-2025
Page Count: 2488
Imprint: Elsevier
List Price: $446.99

Sleisenger and Fordtran's Gastrointestinal and Liver Disease - 2 Volume Set, 12th Edition

by Raymond T. Chung, MD, FAASLD, AASLD, David T. Rubin, MD and Mel Wilcox, MD, MSPH

Hardcover

cover image - Sleisenger and Fordtran's Gastrointestinal and Liver Disease - 2 Volume Set, 12th Edition
ISBN: 9780443116575
Copyright: 2026
Publication Date: 12-10-2025
Page Count: 2488
Imprint: Elsevier
List Price: $446.99
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      • New and expanded discussions of eosinophilic disorders, MASLD (metabolic dysfunction-associated steatotic liver disease, formerly known as non-alcoholic fatty liver disease); the use of AI in endoscopy for improved detection of GI cancers; new treatments for viral hepatitis and autoimmune liver diseases; the expanded array of new treatments for inflammatory bowel disorders; and more
      • New chapters on Gastrointestinal and Hepatic Manifestations of Coronavirus Infection; Enterocolitis and Hepatitis Induced by Cancer Immunotherapy, and a new section on Neoplasia Involving Multiple Organs
      • Reliable coverage of a wide range of endoscopic procedures for diagnosis and treatment, including balloon dilatation, stent placement/removal, and the management of small bowel angioectasia
      • Quick-reference algorithms that summarize clinical decision making and practical approaches to patient management
      • A consistent, templated format throughout the text that enables quick retrieval of information, and more than 20 videos of endoscopic procedures
      • An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date
    • Part I: Biology of the Gastrointestinal Tract
      1. Cellular Growth and Neoplasia
      2. Mucosal Immunology and Inflammation
      3. The Enteric Microbiota
      4. Gut Sensory Transduction
      5. Biopsychosocial Issues in Gastroenterology

      Part II: Nutrition in Gastroenterology
      6. Nutritional Principles and the Assessment of the Gastroenterology Patient
      7. Nutritional Management
      8. Obesity
      9. Surgical and Endoscopic Treatment of Obesity
      10. Feeding and Eating Disorders
      11. Food Allergies

      Part III: Symptoms and Signs
      12. Acute Abdominal Pain
      13. Chronic Abdominal Pain
      14. Symptoms of Esophageal Disease
      15. Dyspepsia
      16. Nausea and Vomiting
      17. Diarrhea
      18. Intestinal Gas
      19. Fecal Incontinence
      20. Constipation
      21. Gastrointestinal Bleeding
      22. Jaundice
      23. Factitious Gastrointestinal Disease

      Part IV: Processes Involving Multiple Organs
      24. Oral Diseases and Oral Manifestations of Gastrointestinal and Liver Diseases
      25. Cutaneous Manifestations of Gastrointestinal and Liver Diseases
      26. Diverticula of the Pharynx, Esophagus, Stomach, and Small Intestine
      27. Abdominal Hernias and Gastric Volvulus
      28. Foreign Bodies, Bezoars, and Caustic Ingestions
      29. Abdominal Abscesses and Gastrointestinal Fistulas
      30. Eosinophilic Disorders of the Gastrointestinal Tract
      31. Protein-Losing Gastroenteropathy
      32. Gastrointestinal and Hepatic Manifestations of Coronavirus Infection
      33. Gastrointestinal Consequences of Infection with Human Immunodeficiency Virus
      34. Gastrointestinal and Hepatic Complications of Solid Organ and Hematopoietic Cell Transplantation
      35. Gastrointestinal and Hepatic Manifestations of Systemic Diseases
      36. Vascular Lesions of the Gastrointestinal Tract
      37. Surgical Peritonitis and Other Diseases of the Peritoneum, Mesentery, Omentum, and Diaphragm
      38. Gastrointestinal and Hepatic Disorders in the Pregnant Patient
      39. Acute and Chronic Gastrointestinal Side Effects of Radiation Therapy
      40. Preparation for and Complications of GI Endoscopy

      Part V: Neoplasia Involving Multiple Organs
      41. Gastrointestinal Lymphomas
      42. Gastrointestinal Stromal Tumors
      43. Neuroendocrine Tumors
      44. Enterocolitis and Hepatitis Induced by Cancer Immunotherapy

      Part VI: Esophagus
      45. Anatomy, Histology, Embryology, and Developmental Anomalies of the Esophagus
      46. Esophageal Neuromuscular Function and Motility Disorders
      47. Esophageal Disorders Caused by Medications, Trauma, and Infection
      48. Gastroesophageal Reflux Disease
      49. Barrett's Esophagus
      50. Esophageal Tumors

      Part VII: Stomach and Duodenum
      51. Anatomy, Histology and Developmental Anomalies of the Stomach and Duodenum
      52. Gastric Neuromuscular Function and Neuromuscular Disorders
      53. Gastric Secretion
      54. Gastritis and Gastropathy
      55. Peptic Ulcer Disease
      56. Adenocarcinoma of the Stomach and Other Gastric Tumors

      Part VIII: Pancreas
      57. Anatomy, Histology, Embryology, and Developmental Anomalies of the Pancreas
      58. Pancreatic Secretion
      59. Genetic Disorders of the Pancreas and Pancreatic Disorders in Childhood
      60. Acute Pancreatitis
      61. Chronic Pancreatitis
      62. Pancreatic Cancer, Cystic Pancreatic Neoplasms, and Other Nonendocrine Pancreatic Tumors
      63. Endoscopic Treatment of Pancreatic Disease

      Part IX: Biliary Tract
      64. Anatomy, Histology, Embryology, Developmental Anomalies, and Pediatric Disorders of the Biliary Tract
      65. Biliary Tract Motor Function and Dysfunction
      66. Bile Formation and Bile Acid Cycling in Health and Disease
      67. Gallstone Disease
      68. Treatment of Gallstone Disease
      69. Acalculous Biliary Pain, Acute Acalculous Cholecystitis, Cholesterolosis, Adenomyomatosis, and Gallbladder Polyps
      70. Primary and Secondary Sclerosing Cholangitis
      71. Tumors of the Bile Ducts, Gallbladder, and Ampulla
      72. Endoscopic and Radiologic Treatment of Biliary Disease

      Part X: Liver
      73. Embryology, Anatomy, Histology, and Developmental Anomalies of the Liver
      74. Liver Physiology and Energy Metabolism
      75. Liver Chemistry and Function Tests
      76. Overview of Cirrhosis
      77. Hemochromatosis
      78. Wilson Disease
      79. Other Inherited Metabolic Disorders of the Liver
      80. Hepatitis A
      81. Hepatitis B
      82. Hepatitis C
      83. Hepatitis D
      84. Hepatitis E
      85. Hepatitis Caused by Other Viruses
      86. Bacterial, Parasitic, and Fungal Infections of the Liver, including Liver Abscess
      87. Vascular Diseases of the Liver
      88. Alcoholic-Associated Liver Disease
      89. Metabolic dysfunction-associated steatotic liver disease/Nonalcoholic fatty liver disease
      90. Liver Disease Caused by Drugs
      91. Liver Disease Caused by Anesthetics, Chemicals, Toxins, and Herbal and Dietary Supplements
      92. Autoimmune Hepatitis
      93. Primary Biliary Cholangitis
      94. Portal Hypertension and Variceal Bleeding
      95. Ascites and Spontaneous Bacterial Peritonitis
      96. Hepatic Encephalopathy, Hepatorenal Syndrome, Hepatopulmonary Syndrome, and Other Systemic Complications of Liver Disease
      97. Acute Liver Failure
      98. Hepatic Tumors and Cysts
      99. Liver Transplantation

      Part XI: Small and Large Intestine
      100. Anatomy, Histology, Embryology, and Developmental Anomalies of the Small and Large Intestine
      101. Small Intestinal Motor and Sensory Function and Dysfunction
      102. Colonic Motor and Sensory Function and Dysfunction
      103. Intestinal Electrolyte Absorption and Secretion
      104. Digestion and Absorption of Carbohydrate, Protein, and Fat
      105. Digestion and Absorption of Micronutrients
      106. Maldigestion and Malabsorption
      107. Small Intestinal Bacterial Overgrowth
      108. Short Bowel Syndrome
      109. Celiac Disease
      110. Tropical Diarrhea and Malabsorption
      111. Whipple Disease
      112. Infectious Enteritis and Proctocolitis
      113. Food Poisoning
      114. Antibiotic-Associated Diarrhea and Clostridium difficile Infection
      115. Intestinal Protozoa
      116. Intestinal Worms
      117. Epidemiology, Pathogenesis and Diagnosis of Inflammatory Bowel Diseases
      118. Management of Inflammatory Bowel Diseases
      119. Ileostomies, Colostomies, and Anastomoses
      120. Intestinal Ischemia
      121. Intestinal Ulcerations
      122. Appendicitis
      123. Diverticular Disease of the Colon
    • Raymond T. Chung, MD, FAASLD, AASLD, Director, Hepatology and Liver Center, Medical Director, Liver Transplant Center, Massachusetts General Hospital/Dana Farber, Boston, Massachusetts, USA, David T. Rubin, MD, Chief, Section of Gastroenterology, Hepatology & Nutrition, Co-Director, Digestive Diseases Center, The University of Chicago Medicine, Chicago, Illinois, USA and Mel Wilcox, MD, MSPH, Professor of Medicine, Director, Division of Gastroenterology and Hepatology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Most review copies are eBooks – how fast!
    A review copy request is most likely to be fulfilled as an eBook on VitalSource rather than a print product, unless no eBook is available. eBooks become available in as little as a few hours. Print products will take between 7 and 10 days to arrive. To request a print copy, please contact us through the Evolve Support Center for further assistance or contact your Elsevier Sales Rep.
    Important note
    You are viewing the faculty version.
    Students requesting access will be reported.
    Important note
    Please note
    This item has low stock levels and may be back-ordered. We'll let you know if it is back-ordered, and you will not be charged until the item ships.