by David A. Morrow, MD, MPH and Robert P. Giugliano, MD, ScM
Hardcover
ISBN: 9780443118692
Copyright: 2026
Publication Date: 12-26-2025
Page Count: 450
Imprint: Elsevier
List Price: $209.99
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Part of the renowned Braunwald family of references, Acute Coronary Syndromes, Second Edition: A Companion to Braunwald’s Heart Disease provides the tools and knowledge you need for effective diagnosis, evaluation, and management of patients with acute coronary syndrome. Concise and easy to use, this fully revised volume explores the most recent tools for diagnosis and therapeutic decision-making, as well as the full range of available management strategies, providing outcomes data for each strategy. This book also includes regular updates with late-breaking clinical trials, reviews of important new articles, and the latest guidance on clinical practice, all selected and masterfully edited by Dr. Eugene Braunwald.
Provides thorough discussions of ECG, established and emerging biochemical markers, angiography, nuclear cardiology, echocardiography, and cardiac MRI and CT
Features an extensive treatment section that covers the latest drugs and most recent clinical trials of antithrombotic therapy, novel anti-inflammatory approaches, coronary revascularization, and approaches to reperfusion injury and ventricular remodeling
Reflects the 2021 ACC/AHA Guidelines for the Evaluation and Diagnosis of Chest Pain, and features increased visual aids such as bulleted lists, graphs, tables, and algorithms throughout
Discusses special considerations for the evaluation of acute coronary syndromes in the emergency department, and use of advanced technologies in cardiac critical care
Covers key topics such as in-hospital complications, cardiogenic shock, transitions to post-discharge care, and cardiac rehabilitation
Includes practice-oriented material that highlights management-focused, practical topics covering expert approaches for areas of uncertainty
Offers guidance on the management of special populations
An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date
1. Overview of the Patient with Acute Coronary Syndrome 2. Classification of acute coronary syndromes
Initial Evaluation and Risk Stratification 3. Pre-hospital assessment and systems of care 4. Clinical approach to suspected acute coronary syndrome 5. Acute cardiac imaging for patients with chest pain in the Emergency Department 6. Risk statification in acute coronary syndromes 7. Emergency department evaluation of the lower risk patient: Who can you send home?
Initial Treatment 8. Selection of reperfusion therapy and transfer strategies for patients with STEMI 9. Fibrinolytic therapy for patients with STEMI 10. Revascularization in non-ST-segment elevation acute coronary syndrome-for whom, when, and how? 11. Approach to percutaneous coronary intervention for acute coronary syndrome 12. Selection of initial anticoagulant therapy 13. Initial antiplatelet therapy for ACS
Inhospital Evaluation 14. Approach to non-invasive testing after presentation with acute coronary syndrome 15. Echocardiography in patients with acute coronary syndrome 16. Nuclear cardiology techniques after acute coronary syndrome 17. Cardiac magnetic resonance imaging after myocardial infarction 18. Optical Coherence Tomography and Other Intracoronary Diagnostic Procedures
In hospital Complications 19. Recurrent ischemia: detection, diagnosis, and outcomes 20. Reperfusion injury: prevention and management 21. Heart failure and cardiogenic shock after ACS 22. Mechanical complications of ACS 23. Arrhythmias and sudden cardiac death after myocardial infarction 24. Epidemiology and management of bleeding in ACS Secondary Prevention after ACS 25. Old and new oral anticoagulant therapy after ACS 26. Antiplatelet therapy after ACS 27. Anti-inflammatory therapy in ACS 28. Management of the patient with ACS in the absence of obstructive coronary artery disease (MINOCA, SCAD, vasospasm) 29. New concepts in cardiac rehabilitation and secondary prevention after ACS 30. Tackling the problem of adverse ventricular remodeling after myocardial infarction
Epidemiolgy and Pathobiology 31. The evolving epidemiology and natural history of acute coronary syndromes 32. New and emerging insights into the pathobiology of acute coronary syndromes, healing, and remodeling
David A. Morrow, MD, MPH, Director, Levine Cardiac Intensive Care Unit Professor of Medicine, Harvard Medical School, Cardiovascular Medicine, Brigham and Women's Hospital, Boston Massachusetts, USA and Robert P. Giugliano, MD, ScM, Associate Professor, Harvard Medical School; Cardiovascular Medicine; Brigham and Women's Hospital, Heart and Vascular Center, Carl J. and Ruth Shapiro Cardiovascular Center, Boston, Massachusetts, USA
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