cover image - Modern Diabetology, 1st Edition
ISBN: 9780443119859
Copyright: 2027
Page Count: 400
Imprint: Elsevier
List Price: $129.99

Modern Diabetology, 1st Edition

by R. Paul Robertson

Paperback

cover image - Modern Diabetology, 1st Edition
ISBN: 9780443119859
Copyright: 2027
Page Count: 400
Imprint: Elsevier
List Price: $129.99

$129.99

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Despite extraordinary therapeutic advances since the discovery of insulin 100 years ago, diabetes prevalence continues to rise and significant challenges remain. Modern Diabetology: Basic Science and Clinical Practice provides a concise, one-stop reference that consolidates rapidly evolving research and clinical practice guidelines for today’s endocrinologists, general surgeons, internists, and primary care physicians.
    • Provides up-to-date coverage of basic science, translational advances, and clinical management in one accessible text, serving as a critical reference for practitioners navigating fast-moving developments in the field
    • Features 24 chapters authored by internationally recognized experts in diabetes research and clinical practice
    • Offers in-depth updates on rapidly advancing areas including MODY, hormonal biology, Types 1 and 2 diabetes genetics, immune mechanisms, and oxidative stress and complications
    • Covers cutting-edge therapeutic strategies such as SGLT2 inhibitors, glucose sensors and pumps, stem cell therapy, and pancreas and islet transplantation
    • An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date
  • Section I: Regulation of Gene Expression, Hormone Synthesis, Hormone Secretion
    1. Pancreatic Development in the Context of Diabetes
    2. Glucagon: From Gene Regulation to Secretion
    3. Insulin Production, Processing, and Secretion
    4. Incretins: From Gene Expression to Secretion and Action of GLP-1 and GIP

    Section II: Hormone Action
    5. Glucagon Synthesis, Secretion and Mechanisms of Action
    6. Insulin Structure and Function
    7. Common Mechanisms of Insulin Signaling, Action, and Resistance
    8. Insulin Receptor Structure and Function
    9. Insulin Action in Liver, Skeletal, Muscle, and Adipose Tissue: A Focus on Humans
    10. Insulin Action in the Brain
    11. Insulin Action in the Cardiovascular System
    12. Metabolic Regulation by Adipokines, Hepatokines, and Myokines

    Section III: Genetics of Diabetes
    13. Genetics of Monogenic Forms of Diabetes
    14. Genetics of Type 1 Diabetes
    15. Genetics of Type 2 Diabetes

    Section IV: Type 1 Diabetes
    16. Spotlight on the Pathology of Type 1 Diabetes

    Section V: Type 2 Diabetes
    17. Heterogeneity of Type 2 Diabetes Mellitus
    18. Cystic Fibrosis Related Diabetes

    Section VI: Complications of Diabetes
    19. Intranuclear Beta Cell Nrf2 EDxpression in Type 2 Diabetes and the Potential Use of Glutathione Peroxidase Mimetics for Early Treatment
    20. Diabetic Retinal Disease
    21. Understanding Diabetic Neuropathy: From Pathophysiology to Therapeutic Targets

    Section VII: Pharmacology and Drugs
    22. SGLT2 Inhibitors and Slowing Kidney Disease Progression from Diabetes
    23. Advanced Technology in Diabetes: Sensors and Pumps
    24. Pancreas and Islet Cell Transplantation for Diabetes
    25. Stem Cell-Derived Islet Therapy for Type 1 Diabetes
  • R. Paul Robertson, Emeritus Professor of Medicine, University of Washington and University of Minnesota, USA

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