ISBN:
9780443249020
Copyright:
2028
Page Count:
416
Imprint:
Elsevier
List Price:
$179.99
Management of HIV Infection in Treatment-Experienced Patients, 1st Edition
by Zelalem Temesgen, MD, FIDSA
Paperback
ISBN:
9780443249020
Copyright:
2028
Page Count:
416
Imprint:
Elsevier
List Price:
$179.99
$179.99
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Expected availability date: 04-01-2027
Designed to assist clinicians in managing an increasing and challenging patient population, Management of HIV Infection in Treatment-Experienced Patients is a practical reference focused on treatment-resistant/treatment-experienced HIV cases. This unique resource combines resistance science (mechanisms, nomenclature, and testing modalities, including genotypic, phenotypic, and archived/proviral DNA testing) with algorithm-driven, scenario-based guidance for building a salvage regimen. Written and edited by experts in this complex field, it clearly and comprehensively covers resistance and treatment failure across the lifespan—from infants through adults—and across settings, whether well-resourced or resource-limited.
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- Provides full coverage of the newest next-generation agents for multidrug-resistant HIV: capsid inhibitors, attachment/post-attachment inhibitors, broadly neutralizing antibodies, and long-acting injectables—including who is and isn't eligible
- Uses a practical, case-anchored writing style with real clinical vignettes integrated throughout
- Covers infants, children, and adolescents (including the transition to adult care) in addition to adult management, and includes a dedicated section on resource-limited settings
- Shares the knowledge and expertise of global, multidisciplinary contributors: physicians, pharmacists, and virologists from the US, UK, Spain, Italy, Netherlands, Canada, and Cameroon
- Discusses under-served topics such as archived/proviral resistance testing interpretation and treatment simplification in already-suppressed patients
- Keeps you up to date with current DHHS, EACS, and WHO guidelines, as well as recent conference/trial data
- Provides access to a 48-minute, case-based video walkthrough of managing early virologic failure, from spotting a blip versus true failure, through live interpretation of resistance mutations in the Stanford HIV Drug Resistance Database, to building the next regimen when treatment fails
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish after the publication date
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1. The Future of Resistance Testing in the Management of People Living With HIV
Part I: Clinical Pharmacology of HIV Therapy
2. Basic Principles of Pharmacokinetics/Pharmacodynamics
3. Antiretroviral Therapy and Drug-Drug Interactions
Part II: Antiretroviral Drug Resistance — General Principles
4. Fundamentals of HIV Drug Resistance
5. Resistance Characteristics of New Drug Classes
Part III: Management of Virologic Failure
6. General Principles and Guideline Recommendations
7. Early Virologic Failure
Part IV: Optimizing Antiretroviral Therapy in the Setting of Virologic Suppression
8. Strategic Treatment Simplification in People Virologically Suppressed on Complex Salvage ART
9. Impact of Archived Mutations in Treatment Simplification
Part V: Managing Antiretroviral Therapy in Special Populations
10. Managing Antiretroviral Therapy in Infants
11. Managing Antiretroviral Therapy in Adolescents
Part VI: Managing Antiretroviral Therapy in Resource-Limited Settings
12. Defining Antiretroviral Treatment Failure in Resource-Limited Settings
13. Management of Treatment Failure in Pediatric and Adolescent Patients in Resource-Limited Settings -
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$179.99
Free Shipping!
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Expected availability date: 04-01-2027
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