cover image - Murray & Nadel's Textbook of Respiratory Medicine, 2-Volume Set, 8th Edition
ISBN: 9780443249730
Copyright: 2027
Publication Date: 10-15-2026
Page Count: 2280
Imprint: Elsevier
List Price: $449.99

Murray & Nadel's Textbook of Respiratory Medicine, 2-Volume Set, 8th Edition

by V. Courtney Broaddus, MD, Nirav R. Bhakta, MD, PhD, Joel D. Ernst, MD, Talmadge E. King Jr, MD, Kathleen F. Sarmiento, MD, Lynn M. Schnapp, MD and Renee D. Stapleton, MD, PhD

Hardcover

cover image - Murray & Nadel's Textbook of Respiratory Medicine, 2-Volume Set, 8th Edition
ISBN: 9780443249730
Copyright: 2027
Publication Date: 10-15-2026
Page Count: 2280
Imprint: Elsevier
List Price: $449.99

$449.99

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Covering the entire spectrum of pulmonology in one authoritative point-of-care resource, Murray & Nadel's Textbook of Respiratory Medicine, 8th Edition, remains the go-to clinical guide and training reference for pulmonary physicians, fellows, and other pulmonary practitioners. Edited and authored by pulmonary experts at the top of their field, it offers definitive, well written, full-color coverage of foundational content, basic science, diagnostic strategies, clinical decision-making, and evidence-based treatment, making it highly relevant for both trainees and seasoned clinicians. This edition includes important new chapters and updates, a streamlined and integrated approach to content, and new author teams that bring fresh perspectives to areas like asthma and COPD management, lung cancer molecular biology and targeted therapies, pleural effusions, interstitial lung disease, and outpatient/inpatient ventilator strategies—enhanced with digital tools and online resources for continuous learning and clinical reference.

    • Provides detailed explanations of each disease entity and differential diagnoses with clinical decision-making guidance, evidence-based content, and diagnostic algorithms, authored by global leaders in the field
    • Reflects the latest advances in respiratory medicine throughout, including diagnostic innovations, breakthrough therapies, and updated clinical guidelines, supporting real-world application and life-long learning
    • Includes new chapters on medical education, pulse oximetry and capnography, obesity hypoventilation, and both noninvasive and invasive ventilation strategies for chronic respiratory failure, as well as extensively revised content on community-acquired pneumonia, sleep disorders, and critical illness—optimized for clinical practice
    • Features more than 1,450 anatomic, algorithmic, and radiologic images, including CT/HRCT, MR, and PET, plus extensive online content: 200 procedural and conceptual videos, audio clips of lung sounds, and new instructional videos on bronchoscopy techniques for self-assessment and clinical training
    • Includes succinct Key Point summaries for each chapter, useful for self-directed learning, self-study exam preparation, and clinical reference
    • Integrates the scientific foundation and genetics into disease-specific chapters for comprehensive understanding and clinical application
    • Brings you up to date with the latest respiratory drugs, mechanisms of action, indications, precautions, adverse effects, and clinical guidelines supported by online resources for ongoing education
    • Sets pulmonary fellows up for success with comprehensive coverage aligned with fellowship curricula—the core knowledge you need to pass your licensing exam and understand the broad range of respiratory medicine for your future career
    • An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish after the publication date
  • VOLUME 1

    Part 1: Scientific Principles of Pulmonary Medicine

    Section A: Anatomy and Development of the Respiratory Tract
    Chapter 1: Anatomy: Structure and Cells
    Chapter 2: Lung Growth and Development
    Chapter 3: Alveolar Compartment
    Chapter 4: Airway Biology
    Chapter 5: The Lung Mesenchyme
    Chapter 6: Vascular Biology
    Chapter 7: Lymphatic Biology
    Chapter 8: Stem Cells and Regeneration

    Section B: Respiratory Physiology
    Chapter 9: Ventilation, Blood Flow, and Gas Exchange
    Chapter 10: Respiratory System Mechanics and Energetics
    Chapter 11: Acid-Base Balance
    Chapter 12: Aerosols and Drug Delivery
    Chapter 13: Control of Breathing and Pathophysiology of Sleep Apnea
    Chapter 14: Pleural Physiology and Pathophysiology

    Section C: Defense Mechanisms and Immunology
    Chapter 15: Innate and Adaptive Immunity
    Chapter 16: Microbiome

    Part 2: Diagnosis and Evaluation of Respiratory Disease

    Section D: Diagnosis
    Chapter 17: History and Physical Examination
    Chapter 18: Microbiologic and Molecular Diagnosis of Lung Infection
    Chapter 19: Thoracic Radiology: Noninvasive Diagnostic Imaging
    Chapter 20: Thoracic Radiology: Invasive Diagnostic Imaging and Image-Guided Interventions
    Chapter 21: Pathology: Neoplastic and Nonneoplastic Lung Disease
    Chapter 22: Ultrasonography: Point-of-Care Principles, Vascular Imaging, and Thoracic Imaging
    Chapter 23: Ultrasonography: Point of Care Evaluation of Cardiac Function and Shock
    Chapter 24: Positron Emission Tomography
    Chapter 25: Diagnostic Bronchoscopy: Basic Techniques
    Chapter 26: Diagnostic Bronchoscopy: Advanced Techniques (EBUS and Navigational)
    Chapter 27: Therapeutic Bronchoscopy
    Chapter 28: Thoracoscopy
    Chapter 29: Thoracic Surgery

    Section E: Evaluation
    Chapter 30: Pulmonary Function Testing: Principles
    Chapter 31: Pulmonary Function Testing: Interpretation and Applications
    Chapter 32: Pulse Oximetry and Capnography
    Chapter 33: Exercise Testing
    Chapter 34: Preoperative Evaluation
    Chapter 35: Evaluation of Respiratory Impairment and Disability

    Part 3: Clinical Respiratory Medicine

    Section F: Evaluation of Common Presentations of Respiratory Disease
    Chapter 36: Dyspnea
    Chapter 37: Cough
    Chapter 38: Chest Pain
    Chapter 39: Wheezing and Stridor
    Chapter 40: Hemoptysis
    Chapter 41: Pulmonary Nodule
    Chapter 42: Aspiration
    Chapter 43: Pulmonary Edema
    Chapter 44: Hypoxemia
    Chapter 45: Hypercapnia

    Section G: Infectious Diseases of the Lungs
    Chapter 46: Community-Acquired Pneumonia: General Features
    Chapter 47: Community-Acquired Pneumonia: Specific Pathogens (Including Severe Acute Respiratory Syndrome Coronavirus 2)
    Chapter 48: Influenza
    Chapter 49: Hospital-Acquired Pneumonia
    Chapter 50: Ventilator-Associated Pneumonia
    Chapter 51: Lung Abscess
    Chapter 52: Tuberculosis: Epidemiology and Prevention
    Chapter 53: Tuberculosis: Pathogenesis and Immunity
    Chapter 54: Tuberculosis: Clinical Manifestations and Diagnosis
    Chapter 55: Tuberculosis: Treatment of Drug-Susceptible and Drug-Resistant
    Chapter 56: Nontuberculous Mycobacterial Infections
    Chapter 57: Fungal Infections: Endemic
    Chapter 58: Fungal Infections: Opportunistic
    Chapter 59: Parasitic Infections
    Chapter 60: Outbreaks, Pandemics, and Bioterrorism

    Section H: Obstructive Diseases
    Chapter 61: Asthma: Pathogenesis and Phenotypes
    Chapter 62: Asthma and Obesity
    Chapter 63: Asthma: Diagnosis and Management
    Chapter 64: COPD: Pathogenesis and Natural History
    Chapter 65: COPD: Diagnosis and Management
    Chapter 66: Smoking Hazards: Cigarettes, Vaping, and Marijuana
    Chapter 67: Tobacco Use Disorder: Treatment
    Chapter 68: Cystic Fibrosis: Pathogenesis and Epidemiology
    Chapter 69: Cystic Fibrosis: Diagnosis and Management
    Chapter 70: Bronchiectasis
    Chapter 71: Upper Airway Disorders
    Chapter 72: Large Airway Disorders
    Chapter 73: Bronchiolitis

    VOLUME 2

    Section I: Neoplasms of the Lungs
    Chapter 74: Lung Cancer: Molecular Biology and Targets
    Chapter 75: Lung Cancer: Epidemiology
    Chapter 76: Lung Cancer: Screening
    Chapter 77: Lung Cancer: Diagnosis and Staging
    Chapter 78: Lung Cancer: Treatment
    Chapter 79: Rare Primary Lung Tumors
    Chapter 80: Metastatic Malignant Tumors
    Chapter 81: Benign Lung Tumors

    Section J: Disorders of Pulmonary Circulation
    Chapter 82: Pulmonary Thromboembolism: Presentation and Diagnosis
    Chapter 83: Pulmonary Thromboembolism: Prophylaxis and Treatment
    Chapter 84: Pulmonary Hypertension: General Approach
    Chapter 85: Pulmonary Arterial Hypertension: Group 1
    Chapter 86: Pulmonary Hypertension Due to Lung Disease: Group 3
    Chapter 87: Pulmonary Hypertension Due to Chronic Thromboembolic Disease: Group 4
    Chapter 88: Pulmonary Vasculitis
    Chapter 89: Pulmonary Vascular Anomalies

    Section K: Infiltrative and Interstitial Lung Diseases
    Chapter 90: Idiopathic Pulmonary Fibrosis
    Chapter 91: Nonspecific Interstitial Pneumonitis and Other Idiopathic Interstitial Pneumonias
    Chapter 92: Hypersensitivity Pneumonitis
    Chapter 93: Connective Tissue Diseases
    Chapter 94: Sarcoidosis
    Chapter 95: Diffuse Alveolar Hemorrhage
    Chapter 96: Pulmonary Langerhans Cell Histiocytosis and Rare Infiltrative Diseases
    Chapter 97: Eosinophilic Lung Diseases
    Chapter 98: Lymphangioleiomyomatosis and Other Cystic Lung Diseases
    Chapter 99: Pulmonary Alveolar Proteinosis Syndrome
    Chapter 100: Drug-Induced Pulmonary Disease

    Section L: Environmental and Occupational Hazards
    Chapter 101: Asthma in the Workplace
    Chapter 102: Pneumoconioses
    Chapter 103: Indoor and Outdoor Air Pollution
    Chapter 104: Acute Pulmonary Responses to Toxic Exposures
    Chapter 105: Trauma and Blast Injuries
    Chapter 106: High Altitude
    Chapter 107: Air Travel
    Chapter 108: Diving Medicine

    Section M: Disorders of the Pleura
    Chapter 109: Pleural Effusion
    Chapter 110: Pleural Infections
    Chapter 111: Pneumothorax
    Chapter 112: Chylothorax
    Chapter 113: Pleural Fibrosis and Nonexpandable Lung
    Chapter 114: Hemothorax
    Chapter 115: Pleural Malignancy

    Section N: Disorders of the Mediastinum
    Chapter 116: Mediastinal Tumors and Cysts
    Chapter 117: Mediastinitis and Fibrosing Mediastinitis

    Section O: Respiratory Manifestations of Extrapulmonary Disorders
    Chapter 118: Pulmonary Complications of HIV Infection
    Chapter 119: Pulmonary Complications of Primary Immunodeficiencies
    Chapter 120: Pulmonary Complications of Stem Cell and Solid Organ Transplantation
    Chapter 121: Pulmonary Complications of Abdominal Diseases
    Chapter 122: Pulmonary Complications of Hematologic Diseases
    Chapter 123: Pulmonary Complications of Endocrine Diseases
    Chapter 124: The Lungs in Obstetric and Gynecologic Diseases
    Chapter 125: The Respiratory System and Neuromuscular Diseases
    Chapter 126: The Respiratory System and Chest Wall Diseases

    Section P: Disorders of Sleep and Control of Breathing
    Chapter 127: Consequences of Sleep Disruption
    Chapter 128: Sleep-Disordered Breathing: A General Approach
    Chapter 129: Obstructive Sleep Apnea
    Chapter 130: Central Sleep Apnea
    Chapter 131: Obesity Hypoventilation Syndrome
    Chapter 132: Sleep-Disordered Breathing: Treatment

    Section Q: Management of Respiratory Failure
    Chapter 133: Acute Ventilatory Failure
    Chapter 134: Acute Respiratory Distress Syndrome
    Chapter 135: Mechanical Ventilation
    Chapter 136: Noninvasive Ventilation for Acute Respiratory Failure
    Chapter 137: Noninvasive and Invasive Ventilation for Chronic Respiratory Failure
    Chapter 138: Noninvasive Support of Oxygenation
    Chapter 139: Extracorporeal Support of Gas Exchange
    Chapter 140: Pulmonary Rehabilitation
    Chapter 141: Lung Transplantation
    Chapter 142: End-of-Life Care in Respiratory Failure
    Chapter 143: Medical Education
  • V. Courtney Broaddus, MD, Professor Emeritus, Division of Pulmonary and Critical Care, University of California, San Francisco, USA, Nirav R. Bhakta, MD, PhD, Associate Professor, Pulmonary, Critical Care, Allergy, and Sleep Medicine, University of California, San Francisco, USA, Joel D. Ernst, MD, Professor and Chief, Division of Experimental Medicine, University of California, San Francisco, USA, Talmadge E. King Jr, MD, Dean, UCSF School of Medicine, Vice Chancellor, Medical Affairs, University of California, San Francisco, USA, Kathleen F. Sarmiento, MD, Professor, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA, Lynn M. Schnapp, MD, George R. and Elaine Love Professor Chair of the Department of Medicine University of Wisconsin School of Medicine and Public Health Madison, WI, USA and Renee D. Stapleton, MD, PhD, Professor of Medicine, Pulmonary and Critical Care Medicine, Larner College of Medicine, University of Vermont, USA
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