Waller's Medical Pharmacology and Therapeutics, 7th Edition

• A clinical focus throughout – suitable for medical, nursing and other healthcare students throughout their training • Thorough update of clinically-relevant medicines to ensure best practice • Information aligned with the British National Formulary (BNF), NICE guidelines and relevant professional benchmarks • Comprehensive drug compendia allow all drugs to be identified and placed within their respective classes • Extensive self-assessment questions to support learning and revision

Preface Drug Dosage and Nomenclature

SECTION 1 GENERAL PRINCIPLES
1. Principles of Pharmacology and Mechanisms of Drug Action
2. Pharmacokinetics
3. Drug Discovery, Safety and Efficacy
4. Neurotransmission and the Peripheral Autonomic Nervous System

SECTION 2 THE CARDIOVASCULAR SYSTEM
5. Ischaemic Heart Disease
6. Systemic and Pulmonary Hypertension
7. Heart Failure and Shock
8. Cardiac Arrhythmias
9. Cerebrovascular Disease and Dementia
10. Peripheral Artery Disease
11. Haemostasis

SECTION 3 THE RESPIRATORY SYSTEM
12. Asthma and Chronic Obstructive Pulmonary Disease
13. Respiratory Disorders: Cough, Respiratory Stimulants, Cystic Fibrosis, Idiopathic Pulmonary Fibrosis and Neonatal Respiratory Distress Syndrome

SECTION 4 THE RENAL SYSTEM
14. Diuretics
15. Disorders of Micturition
16. Erectile Dysfunction

SECTION 5 THE NERVOUS SYSTEM
17. General Anaesthetics
18. Local Anaesthetics
19. Opioid Analgesics and the Management of Pain
20. Anxiety, Obsessive-Compulsive Disorder and Insomnia
21. Schizophrenia and Bipolar Disorder
22. Depression, Attention Deficit Hyperactivity Disorder and Narcolepsy
23. Seizures and Epilepsy
24. Extrapyramidal Movement Disorders and Spasticity
25. Other Neurological Disorders: Multiple Sclerosis, Motor Neuron Disease and Guillain-Barré Syndrome
26. Migraine and Other Headaches

SECTION 6 THE MUSCULOSKELETAL SYSTEM
27. The Neuromuscular Junction and Neuromuscular Blockade
28. Myasthenia Gravis
29. Nonsteroidal Anti-inflammatory Drugs
30. Rheumatoid Arthritis, Other Inflammatory Arthritides and Osteoarthritis
31. Hyperuricaemia, Gout and Pseudogout

SECTION 7 THE GASTROINTESTINAL SYSTEM
32. Nausea and Vomiting
33. Dyspepsia, Peptic Ulcer Disease and Gastrooesophageal Reflux Disease
34. Inflammatory Bowel Disease
35. Constipation, Diarrhoea and Irritable Bowel Syndrome
36. Liver Disease
37. Obesity

SECTION 8 THE IMMUNE SYSTEM
38. The Immune Response and Immunosuppressant Drugs
39. Antihistamines and Allergic Disease

SECTION 9 THE ENDOCRINE SYSTEM AND METABOLISM
40. Diabetes Mellitus
41. The Thyroid and Control of Metabolic Rate
42. Calcium Metabolism and Metabolic Bone Disease
43. Pituitary and Hypothalamic Hormones
44. Corticosteroids (Glucocorticoids and Mineralocorticoids)
45. Female Reproduction
46. Androgens, Antiandrogens and Anabolic Steroids
47. Anaemia and Haematopoietic Colony-Stimulating Factors
48. Lipid Disorders

SECTION 10 THE SKIN AND EYES
49. Skin Disorders 50. The Eye

SECTION 11 CHEMOTHERAPY
51. Drugs for Infections
52. Drugs for Cancer

SECTION 12 GENERAL FEATURES, TOXICITY AND PRESCRIBING
53. Drug Toxicity and Overdose
54. Substance Abuse and Dependence
55. Prescribing, Adherence and Information About Medicines
56. Drug Therapy in Special Situations Index

Derek G. Waller, BSc, DM, MBBS, FRCP, Former Consultant Physician and Senior Clinical Lecturer, Department of Medicine, University Hospital Southampton, Southampton, UK, Andrew W. Hitchings, BSc, MBBS, PhD, FRCP, FFICM, FHEA, FBPhS, Reader in Clinical Pharmacology, St George’s, University of London, Honorary Consultant in Neurointensive Care, St George’s University Hospitals NHS Foundation Trust, London, UK, Dagan Lonsdale, BSc(Hons) MBBS PhD MRCP FHEA FFICM, Honorary Senior Lecturer, St George’s, University of London; Specialty Registrar in Clinical Pharmacology, General Medicine and Intensive Care Medicine, St George’s University Hospitals NHS Foundation Trust, London, UK and Emily J. Swindle, PhD, Associate Professor in Pharmacology GI Module Lead, Pharmacology Subject Lead and PSA Academic Assessment Lead (BMBS) Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UK