Benzon and Raja's Essentials of Pain Medicine, 5th Edition

Section 1: Basic Considerations
1. Anatomy and Physiology of the Pain-Signaling Process
2. Neurochemistry of Somatosensory and Pain Processing
3. Taxonomy: Definition of Pain Terms and Chronic Pain Syndromes

Section 2: Clinical Evaluation and Diagnostic Examinations
4. Physical Examination of the Patient with Pain
5. Pain Assessment
6. Psychological Evaluation and Testing
7. Diagnostic and Statistical Manual of Mental Disorders and Pain Management
8. Neurophysiologic Testing for Pain
9. Anatomy, Imaging, and Common Pain-Generating Degenerative Pathologies of the Spine
10. Brain Imaging and Biomarkers in the Diagnosis and Management of Chronic Pain
11. Determination of Disability

Section 3: Perioperative Pain Management
12. Trajectories of Postoperative Pain and Opioid Use
13. Opioid-Free Anesthesia
14. Perioperative Nonopioid Infusions and Patient-Controlled Analgesia for Postoperative Pain Management
15. Neuraxial (Epidural and Intrathecal) Opioids for Postoperative Pain
16. The Role of Perioperative Nerve Blocks in Postoperative Pain
17. Pediatric Postoperative Pain Management
18. Chronic Postsurgical Pain
19. Pharmacogenetics for Perioperative and Chronic Pain Management
20. Virtual Reality/Imagery to Reduce Postoperative and Chronic Pain

Section 4: Chronic Pain Syndromes
21. Migraine Headache and the Trigeminal Autonomic Cephalalgias
22. Tension-Type Headache, Chronic Tension-Type Headache, and Other Headache Types
23. Post–Dural Puncture Headache and Spontaneous Intracranial Hypotension
24. Cervicogenic Headache
25. Orofacial Pain
26. Overview of Low Back Pain Disorders
27. Myofascial Pain Syndrome
28. Fibromyalgia and Centralized Pain States
29. Management of Rheumatologic Pain
30. Complex Regional Pain Syndrome
31. Herpes Zoster and Postherpetic Neuralgia
32. Postamputation Pain
33. Central Neuropathic Pain
34. Managing Musculoskeletal Causes of Pelvic Pain
35. Diabetic Painful Neuropathy and Other Peripheral Neuropathies
36. Entrapment Neuropathies

Section 5: Management of Pain in Specific Situations
37. Management of Cancer Pain and Pain at End of Life
38. Pain Management in the Emergency Department
39. Chronic Pain Management in Children and Adolescents
40. Geriatric Pain
41. Pain Management During Pregnancy and Lactation
42. Pain Control in the Critically Ill Patient

Section 6: Pharmacologic and Other Modalities
43. Major Opioids in Pain Management
44. Opioids Used for Mild to Moderate Pain
45. Nonopioid Analgesics
46. Psychopharmacology for Pain Medicine
47. Membrane Stabilizers
48. Pharmacologic Management of Myofascial Pain
49. Intravenous Infusions for Chronic Pain Management
50. Pharmacology for the Interventional Pain Physician
51. Role of Cannabinoids in Pain Management
52. The Prescription Drug Abuse Epidemic and Emerging Prescribing Guidelines
53. Legal and Regulatory Issues in Pain Management
54. Urine Drug Testing in Pain Medicine
55. Substance Use Disorders and Withdrawal Management

Section 7: Therapeutic Interventions
56. Ablative Neurosurgical Procedures for Treatment of Chronic Pain
57. Physical Medicine and Rehabilitation Approaches to Pain Management
58. Psychological Interventions for Chronic Pain
59. Role of Acupuncture and Tai Chi in Chronic Pain Management
60. Artificial Intelligence in Pain Medicine

Section 8: Interventional Techniques for Pain Management
61. Interlaminar Epidural Corticosteroid Injections
62. Selective Nerve Root Blocks and Transforaminal Epidural Corticosteroid Injections
63. Facet Joint Syndrome
64. Sacroiliac Joint Pain
65. Radiofrequency Ablation and Cryoneurolysis
66. Vertebroplasty and Kyphoplasty
67. Minimally Invasive Surgery for Chronic Low Back Pain
68. Spinal Cord Stimulation
69. Peripheral Nerve Stimulation
70. Dorsal Root Ganglion Stimulation
71. Implanted Drug Delivery Systems for Control of Chronic Pain
72. Fluoroscopy and Radiation Safety

Section 9: Nerve Blocks and Miscellaneous Topics
73. Head and Neck Blocks
74. Truncal Blocks: Paravertebral, Erector Spinae Plane, Intercostal, Pectoral, Suprascapular, Ilioinguinal, Iliohypogastric, Quadratus Lumborum, Rectus Sheath, External Oblique Intercostal Plane, and Transversus Abdominis Plane Blocks
75. Sympathetic Blocks and Neurolysis: Mechanisms, Indications, and Clinical Applications
76. Injections for Piriformis, Iliopsoas Tendinopathy, and Thoracic Outlet Syndrome
77. Ultrasound-Guided Injections into Shoulder, Hip, and Knee Joints and Radiofrequency Treatment for Hip and Knee Pain
78. Interventional Pain Procedures in Patients on Anticoagulants
79. Interventional Pain Procedures and the Risk of Infection

Section 10: Research Topics Essential to Pain Management
80. Research Approaches and Their Reporting in Regional Anesthesia and Perioperative and Chronic Pain Management
81. Fundamentals of Research Designs for Clinical Trials of Pain Treatment

Honorio Benzon, MD, Professor Emeritus of Anesthesiology, Associate Chair for Academic Affairs and Promotions, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA, Srinivasa N. Raja, MD, Professor of Anesthesiology, Critical Care Medicine and Neurology, Director of Pain Research, Division of Pain Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA, Steven P. Cohen, MD, Edmond I Eger Professor of Anesthesiology, Vice Chair, Research and Pain Medicine, Departments of Anesthesiology, Neurology, PM&R, Psychiatry and Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, and Director, Pain Research, Walter Reed National Military Medical Center, Uniformed Services University of the Health Sciences, Bethesda, Maryland, Anuj Bhatia, MBBS, MD, PhD, FRCA, FFPMRCA, FRCPC (Anesthesia & Pain Medicine), EDRA, CIPS, ASRA-PMUC, FIPP, Professor, University of Toronto; Director, Comprehensive Integrated Pain Program, Staff, Department of Anesthesia and Pain Management, Toronto Western Hospital, Toronto, Ontario, Canada, Ariana M. Nelson, MD, MEHP, Associate Clinical Professor, Department of Anesthesiology and Perioperative Care, University of California, Irvine, Irvine, California; NASA Exploration Medical Capabilities Element, University of Texas, Medical Branch, USA and Harsha Shanthanna, MD, PhD, Professor, Department of Anesthesia, Departments of Surgery, Health Research Methods, Evidence, and Impact (HEI), School of Biomedical Engineering, McMaster University, Hamilton, Ontario, Canada