An essential, practical guide for neurologists, psychiatrists, geriatricians, and others who work with the elderly, Memory Loss, Alzheimer's Disease, and Dementia: A Practical Guide for Clinicians, 4th Edition, provides up-to-date information on detection, diagnosis, and treatment—including recent, significant medical advancements, drug therapies, and research. Drs. Andrew E. Budson and Paul R. Solomon focus on the day-to-day tools clinicians need, thoroughly covering the essentials of physical and cognitive examinations plus laboratory and imaging studies for dementia and related illnesses. This fully revised edition is particularly timely in a field that is experiencing tremendous progress and change in numerous areas, and contains authoritative, real-world guidance to help you make accurate diagnosis and treatment decisions with confidence.
Contains fully updated content from cover to cover, with a new chapter on Amyloid-Targeting Therapies, information on newly FDA-approved drugs for treatment (donanemab, benzgalantamine, and lecanemab) as well as discontinued drugs that must be phased out, and newly revised criteria for diagnosis and staging of Alzheimer's disease
Covers recent advances in the understanding of blood, plasma, and imaging biomarkers for the diagnosis of AD and related disorders; advances in understanding genetic causes; new developments in lifestyle interventions and technology, such as wearable devices; and recent progress in blood testing for accurate diagnosis
Provides comprehensive coverage of hot topics such as chronic traumatic encephalopathy (CTE), primary age-related tauopathy (PART), and limbic-predominant, age-related TDP-43 encephalopathy (LATE)
Incorporates real-world case studies that facilitate the management of both common and uncommon conditions
Reflects current National Institute on Aging–Alzheimer's Association and DSM-5-TR criteria for Alzheimer’s disease, mild cognitive impairment, and related disorders
Provides access to dozens of videos that illustrate common tests, clinical signs, and diagnostic features
Features Quick Start boxes at the top of every chapter to inform your clinical approach, as well as diagrams, charts, patient brain imaging studies, pathology images, and anatomical illustrations to visually support the text
An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, make notes and highlights, and have content read
[NOT FINAL - DO NOT POST ON PUBLIC-FACING SITE] Section I 1. Why Diagnose and Treat Memory Loss, Alzheimer’s Disease, and Dementia 2. Evaluating the Patient With Memory Loss or Dementia 3. Subjective Cognitive Decline, Mild Cognitive Impairment, and Dementia
Section II 4. Alzheimer’s Disease 5. Primary Age-Related Tauopathy 6. Limbic-predominant Age-related TDP-43 Encephalopathy 7. Vascular Cognitive Impairment and Vascular Dementia 8. Dementia With Lewy Bodies 9. Primary Progressive Aphasia and Apraxia of Speech 10. Behavioral Variant Frontotemporal Dementia 11. Posterior Cortical Atrophy 12. Progressive Supranuclear Palsy 13. Corticobasal Degeneration and Corticobasal Syndrome 14. Normal Pressure Hydrocephalus
Section III 15. Chronic Traumatic Encephalopathy 16. Creutzfeldt–Jakob Disease 17. Other Disorders That Cause Memory Loss or Dementia 18. Goals for the Treatment of Memory Loss, Alzheimer’s Disease, and Dementia 19. Cholinesterase Inhibitors 20. Memantine
Section IV 21. Vitamins, Herbs, Supplements, and Antiinflammatories 22. Nonpharmacological Treatment of Memory Loss, Alzheimer’s Disease, and Dementia 23. [FUTURE THERAPIES CHAPTER REPLACED WITH NEW CHAPTER] 24. Evaluating the Behavioral and Psychological Symptoms of Dementia
Section V 25. Caring for and Educating the Caregiver 26. Nonpharmacological Treatment of the Behavioral and Psychological Symptoms of Dementia 27. Pharmacological Treatment of the Behavioral and Psychological Symptoms of Dementia 28. Life Adjustments for Memory Loss, Alzheimer’s Disease, and Dementia 29. Legal and Financial Issues in Memory Loss, Alzheimer’s Disease, and Dementia 30. Special Issues in Memory Loss, Alzheimer’s Disease, and Dementia
Andrew E. Budson, MD, Chief, Cognitive and Behavioral Neurology and Associate Chief of Staff for Education, Veterans Affairs Boston Healthcare SystemProfessor of Neurology, Boston University School of Medicine, Newton, MA, USA and Paul R. Solomon, PhD, Department of Psychology, Williams College, Williamstown, MA, Newton, MA, USA
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