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cover image - Ocular Disease: Mechanisms and Management,1st Edition
ISBN: 9780702029837
Publication Date: 03-03-2010
Page Count: 704
Imprint: Saunders
List Price: $152.00

Ocular Disease: Mechanisms and Management, 1st Edition

by Leonard A Levin, MD, PhD and Daniel M. Albert, MD, MS


cover image - Ocular Disease: Mechanisms and Management,1st Edition
ISBN: 9780702029837
Publication Date: 03-03-2010
Page Count: 704
Imprint: Saunders


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Ocular Disease—a newly introduced companion volume to the classic Adler’s Physiology of the Eye—correlates basic science and clinical management to describe the how and why of eye disease processes and the related best management protocols. Editors Leonard A. Levin and Daniel M. Albert—two of the world’s leading ophthalmic clinician-scientists—have recruited as contributors the most expert and experienced authorities available in each of the major areas of ophthalmic disease specific to ophthalmology: retina, cornea, cataract, glaucoma, uveitis, and more. The concise chapter structure features liberal use of color—with 330 full-color line artworks, call-out boxes, summaries, and schematics for easy navigation and understanding. In print and online at, this comprehensive resource provides you with a better and more practical understanding of the science behind eye disease and its relation to treatment.

    • Includes access to the fully searchable text online at, along with images and references.
    • Covers all areas of disease in ophthalmology including retina, cornea, cataract, glaucoma, and uveitis for the comprehensive information you need for managing clinical cases.
    • Presents a unique and pragmatic blend of necessary basic science and clinical application to serve as a clinical guide to understanding the cause and rational management of ocular disease.
    • Features 330 full-color line artworks that translate difficult concepts and discussions into concise schematics for improved understanding and comprehension.
    • Provides the expert advice of internationally recognized editors with over 40 years of experience together with a group of world class contributors in basic science and clinical ophthalmology.
  • SECTION 1 Cornea

    1. Loss of corneal transparency

    Russell L McCally

    2. Abnormalities of corneal wound healing

    Audrey M Bernstein

    3. Wound healing after laser in situ keratomileusis and photorefractive keratectomy

    Fabricio Witzel de Medeiros and Steven E Wilson

    4. Genetics and mechanisms of hereditary corneal dystrophies

    John D Gottsch

    5. Fuchs’ endothelial corneal dystrophy

    Vinay Gutti, David S Bardenstein, Sudha Iyengar, and Jonathan H Lass

    6. Keratoconus

    M Cristina Kenney and Ronald N Gaster

    7. Infectious keratitis

    Michael S Gilmore, Susan R Heimer, and Ai Yamada

    8. Corneal graft rejection

    Daniel R Saban, Mohammad H Dastjerdi, and Reza Dana

    9. Corneal edema

    Daniel G Dawson and Henry F Edelhauser

    10. Corneal angiogenesis and lymphangiogenesis

    Chih-Wei Wu, David Ellenberg, and Jin-Hong Chang

    11. Ocular surface restoration

    Julie T Daniels, Genevieve A Secker, and Alex J Shortt

    12. Herpetic keratitis

    Pranita P Sarangi and Barry T Rouse

    13. Ocular allergy

    Neal P Barney, Ellen B Cook, James L Stahl, and Frank M Graziano

    SECTION 2 Dry eye

    14. The lacrimal gland and dry-eye disease

    Darlene A Dartt

    15. Immune mechanisms of dry-eye disease

    Austin K Mircheff and Joel E Schechter

    16. Disruption of tear ?lm and blink dynamics

    Jianhua Wang and Anuj Chauhan

    17. Abnormalities of eyelid and tear ?lm lipid

    Gary N Foulks and Douglas Borchman

    18 Dry eye: abnormalities of tear ?lm mucins

    Ann-Christin Albertsmeyer and Ilene K Gipson

    SECTION 3 Glaucoma

    19. Steroid-induced glaucoma

    Abbot F Clark, Xinyu Zhang, and Thomas Yorio

    20. Biomechanical changes of the optic disc

    Ian A Sigal, Michael D Roberts, Michael JA Girard, Claude F Burgoyne, and J Crawford Downs

    21. Pigmentary dispersion syndrome and glaucoma

    Michael G Anderson

    22. Abnormal trabecular meshwork out?ow

    Paul A Knepper and Beatrice YJT Yue

    23. Pressure-induced optic nerve damage

    James C Tsai

    24. Exfoliation (pseudoexfoliation) syndrome

    Robert Ritch and Ursula Schlötzer-Schrehardt

    25. Angle closure glaucoma

    Shamira Perera, Nishani Amerasinghe, and Tin Aung

    26. Central nervous system changes in glaucoma

    Yeni N Yücel and Neeru Gupta

    27. Retinal ganglion cell death in glaucoma

    Heather R Pelzel and Robert W Nickells

    28. Wound-healing responses to glaucoma surgery

    Stelios Georgoulas, Annegret Dahlmann-Noor, Stephen Brocchini, and Peng Tee Khaw

    29. Blood ?owchanges in glaucoma

    Leopold Schmetterer and Mark Lesk

    SECTION 4 Lens

    30. Biochemical mechanisms of age-related cataract

    David C Beebe, Ying-Bo Shui, and Nancy M Holekamp

    31. Posterior capsule opaci?cation

    Judith West-Mays and Heather Sheardown

    32. Diabetes-associated cataracts

    Peter F Kador

    33. Steroid-induced cataract

    Abbas Samadi

    34. Presbyopia

    Jane F Koretz

    35. Restoration of accommodation

    Stephen D McLeod and Michelle Trager Cabrera

    36. Intraoperative ?oppy iris syndrome

    Amy Lin and Roger F Steinert

    SECTION 5 Neuro-ophthalmology

    37. Optic neuritis

    John R Guy and Xiaoping Qi

    38. Abnormal ocular motor control

    James A Sharpe and Arun Sundaram

    39. Idiopathic intracranial hypertension (idiopathic pseudotumor cerebri)

    Deborah M Grzybowski and Martin Lubow

    40. Giant cell arteritis

    Lynn K Gordon

    41. Ischemic optic neuropathy

    Helen Danesh-Meyer

    42. Optic nerve axonal injury

    Daniela Toffoli and Leonard A Levin

    43. Leber’s hereditary optic neuropathy

    Alfredo Sadun and Alice Kim

    44. Optic atrophy

    Nathan T Tagg and Randy H Kardon

    45. Nystagmus

    Frank Proudlock and Irene Gottlob

    46. Toxic optic nerve neuropathies

    FT "Fritz" Fraunfelder and FW "Rick" Fraunfelder

    SECTION 6 Oncology

    47. Uveal melanoma

    Zélia MS Corrêa and J William Harbour

    48. Genetics of hereditary retinoblastoma

    Alejandra G de Alba Campomanes and Joan M O’Brien

    49. Molecular basis of low-penetrance retinoblastoma

    Katie Matatall and J William Harbour

    50. Vasculogenic mimicry

    Robert Folberg and Andrew J Maniotis

    51. Treatment of choroidal melanoma

    Aimee V Chappelow and Andrew P Schachat

    52. Sebaceous cell carcinoma

    Alon Kahana, Jonathan T Pribila, Christine C Nelson, and Victor M Elner

    53. Neuro?bromatosis

    Robert Listernick and David H Gutmann

    SECTION 7 Other

    54 Phthisis bulbi

    Ingo Schmack, Hans E Völcker, and Hans E Grossniklaus

    55. Myopia

    Terri L Young

    56. Pathogenesis of Graves’ ophthalmopathy

    A Reagan Schiefer and Rebecca S Bahn

    SECTION 8 Pediatrics

    57. Duane syndrome

    Joseph L Demer

    58. Amblyopia

    Robert F Hess and Nigel Daw

    59 Strabismus

    Christopher S von Bartheld, Scott A Croes, and L Alan Johnson

    60. Albinism

    Gerald F Cox and Anne B Fulton

    61. Aniridia

    Elias I Traboulsi

    SECTION 9 Retina

    62. Color vision defects

    Maureen Neitz and Jay Neitz

    63. Acute retinal vascular occlusive disorders

    Sohan Singh Hayreh

    64. Retinal photic injury: laboratory and clinical ?ndings

    Daniel Organisciak and Marco Zarbin

    65. Vascular damage in diabetic retinopathy

    Timothy S Kern and Suber Huang

    66. Neovascularization in diabetic retinopathy

    Corey B Westerfeld and Joan W Miller

    67. Diabetic macular edema

    Pascale Massin, Michel Paques, and Jean-Antoine Pournaras

    68. Dry age-related macular degeneration and age-related macular degeneration pathogenesis

    Marco Zarbin and Janet S Sunness

    69. Neovascular age-related macular degenerationDavid E Lederer, Scott W Cousins, and Karl G Csaky

    70. Inhibition of

  • Leonard A Levin, MD, PhD, Canada Research Chair of Ophthalmology and Visual Sciences, Univerisity of Montreal, Montreal, Quebec, Canada; Professor of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI, USA Canada Research Chair of Ophthalmology and Visual Sciences Department of Ophthalmology University of Montreal and Professor and Daniel M. Albert, MD, MS, F.A. Davis Professor, Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health; Founding Director, University of Wisconsin McPherson Eye Research Institute, Madison, WI, USA


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