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Rang & Dale's Pharmacology Elsevier eBook on VitalSource, 8th Edition
Elsevier eBook on VitalSource®

Rang & Dale's Pharmacology Elsevier eBook on VitalSource, 8th Edition

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For 25 years, Rang and Dale’s Pharmacology has delivered the core basic and clinical science information required by students and healthcare practitioners worldwide. Authors H. P. Rang, J. M. Ritter, R. J. Flower, and G. Henderson have ensured that the 8th Edition of this easy-to-read, comprehensive text continues the tradition of excellence with new coverage of drugs affecting the skin and new components online at Student Consult.

    • Get the essential pharmacology information you need from one authoritative source with an outstanding global reputation for excellence.

    • Progress confidently through all relevant aspects of pharmacology, beginning with a molecular understanding of receptors and drug actions through clinical uses of key groups of drugs.

    • Find important content quickly thanks to a color-coded layout that enables easy navigation and cross-referencing.

    • Master difficult concepts with Key Points boxes, Clinical Uses boxes, and full-color illustrations throughout.
      • Stay up to date with new information in the field, including an all-new chapter on drugs that affect the skin.

      • Take advantage of new and unique features online, including 500+ chapter-specific multiple choice questions for immediate self-assessment.

      • eBook version included! For the first time, you can access the entire book online or offline across all devices with the Student Consult eBook!

      Section 1: General principles

      1. What is pharmacology?

      2. How drugs act: general principles

      3. How drugs act: molecular aspects

      4. How drugs act: cellular aspects—excitation, contraction and secretion

      5. Cell proliferation, apoptosis, repair and regeneration

      6. Cellular mechanisms: host defence

      7. Method and measurement in pharmacology

      8. Drug absorption and distribution

      9. Drug metabolism and elimination

      10. Pharmacokinetics

      11. Pharmacogenetics, pharmacogenomics and ‘personalised medicine’

      Section 2: Chemical mediators

      12. Chemical mediators and the autonomic nervous system

      13. Cholinergic transmission

      14. Noradrenergic transmission

      15. 5-Hydroxytryptamine and the pharmacology of migraine

      16. Purines

      17. Local hormones: cytokines, biologically active lipids, amines and peptides

      18. Cannabinoids

      19. Peptides and proteins as mediators

      20. Nitric oxide

      Section 3: Drugs affecting major organ systems

      21. The heart

      22. The vascular system

      23. Atherosclerosis and lipoprotein metabolism

      24. Haemostasis and thrombosis

      25. Haemopoietic system and treatment of anaemia

      26. Anti-inflammatory and immunosuppressant drugs

      27. The respiratory system

      28. The kidney

      29. The gastrointestinal tract

      30. The control of blood glucose and drug treatment of diabetes mellitus

      31. Obesity

      32. The pituitary and the adrenal cortex

      33. The thyroid

      34. The reproductive system

      35. Bone metabolism

      Section 4: The nervous system

      36. Chemical transmission and drug action in the central nervous system

      37. Amino acid transmitters

      38. Other transmitters and modulators

      39. Neurodegenerative diseases

      40. General anaesthetic agents

      41. Analgesic drugs

      42. Local anaesthetics and other drugs affecting sodium channels

      43. Anxiolytic and hypnotic drugs

      44. Antiepileptic drugs

      45. Antipsychotic drugs

      46. Antidepressant drugs

      47. CNS stimulants and psychotomimetic drugs

      48. Drug addiction, dependence and abuse

      Section 5: Drugs used for the treatment of infections, cancer and immunological disorders

      49. Basic principles of antimicrobial chemotherapy

      50. Antibacterial drugs

      51. Antiviral drugs

      52. Antifungal drugs

      53. Antiprotozoal drugs

      54. Anthelminthic drugs

      55. Anticancer drugs

      Section 6: Special topics

      56. Individual variation and drug interaction

      57. Harmful effects of drugs

      58. Lifestyle drugs and drugs in sport

      59. Biopharmaceuticals and gene therapy

      60. Drug discovery and development

      Humphrey P. Rang, MB BS MA DPhil Hon FBPharmacolS FMedSci FRS, Emeritus Professor of Pharmacology, University College London, London, UK, James M. Ritter, DPhil FRCP FBPharmacolS FMedSci, Emeritus Professor of Clinical Pharmacology, King’s College London, and Medical Research Director, Quintiles, London, UK, Rod J. Flower, PhD DSc FBPharmacolS FMedSci FRS, Professor, Biochemical Pharmacology, The William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London , London, UK and Graeme Henderson, BSc PhD FBPharmacolS FSB, Professor of Pharmacology, University of Bristol, Bristol, UK

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