Immunology Elsevier Elsevier eBook on Vitalsource, 9th Edition

Explains the building blocks of the immune system - cells, organs, and major receptor molecules - as well as initiation and actions of the immune response, especially in a clinical context.

Features a reorganized format that presents immunology in the order in which is typically taught and learned, better integrating basic and clinical immunology.

Provides Critical Thinking boxes, chapter-opening summaries, and case-based and USMLE-style questions that provide effective review and quick practice for exams – plus more learning opportunities online, including USMLE-style questions and clinical cases.

Includes extensive updates to clinical information, including recent clinical approaches in cancer immunology, transplantation, autoimmunity, hypersensitivity, and more.

Covers new topics such as innate lymphoid cells, antibody-based therapies and antibody engineering, innate immunity and its components, the genetics of immunologically-based diseases and personalized medicine, and immunotherapeutic agents for the treatment of cancer.

SECTION 1 The Immune System and Innate Immunity

1 Introduction to the Immune System

2 Cells, Tissues and Organs of the Immune System

3 Mechanisms of Innate Immunity

4 Complement

5 Mononuclear Phagocytes in Immune Defence

SECTION 2 Adaptive Immune Responses

6 T-Cell Receptors and Major Histocompatibility Complex Molecules

7 Antigen Presentation

8 Cell-Mediated Cytotoxicity

9 B-Cell Development and the Antibody Response

10 Antibodies

11 Immunological Tolerance

12 Regulation of the Immune Response

13 Immune Responses in Tissues

SECTION 3 Defence Against Infectious Agents

14 Immunity to Viruses

15 Immunity to Bacteria and Fungi

16 Immunity to Protozoa and Worms

17 Vaccination

SECTION 4 Immunodeficiency

18 Primary Immunodeficiencies

19 AIDS, Secondary Immunodeficiency and Immunosuppression

SECTION 5 Immune Responses Against Tissues

20 Autoimmunity and Autoimmune Disease

21 Transplantation and Rejection

22 Immunity to Cancers

SECTION 6 Hypersensitivity

23 Immediate Hypersensitivity (Type I)

24 Hypersensitivity (Type II)

25 Hypersensitivity (Type III)

26 Hypersensitivity (Type IV)

David Male, MA, PhD, Professor of Biology, Department of Life Sciences, The Open University, Milton Keynes, United Kingdom, R. Stokes Peebles, Jr., MD, Professor of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center and Victoria Male, MA, PhD, Sir Henry Dale Fellow, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom