Clinical Chemistry, 9th Edition
Clinical Chemistry considers what happens to the body’s chemistry when affected by disease. It provides introductory coverage of the scientific basis for biochemistry tests routinely used in medicine - including tests for the assessment of organ function, diagnosis and monitoring disease activity and therapy efficacy. Each topic area begins with a concise description of the underlying physiological and biochemical principles and then applies them to patient investigation and management. The regular use of case histories helps further emphasise clinical relevance and chapter key points, as well as provide a useful starting point for examination revision.
The clear and engaging writing style appreciated by generations of readers has been retained in this ninth edition, while the content has been thoroughly updated throughout. The approach and scope of this trusted text makes it ideal for integrated medical curricula, for medical training and for students and practitioners of clinical and biomedical science. The complementary eBook version, including additional cases and self-assessment material, completes this superb learning package.
- Updated to incorporate the latest changes in practice – including new tests and the most recent evidence-based guidance – plus a new chapter on clinical chemistry in pediatrics.
- Figures, tables, boxes, and case studies aid understanding and learning.
- ‘Light bulb’ sections give practical advice and clarify difficult concepts or potential pitfalls.
- New ‘Red flag’ boxes highlight the results which should cause immediate concern to clinicians.
- Updated references to core guidelines reflect latest best practice.
- BONUS materials on Student Consult include interactive clinical cases and MCQs - to reinforce interpretive skills, check understanding and aid exam preparation.
- Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
1. An Introduction to Biochemistry and Cell Biology
2. Biochemical Investigations in Clinical Medicine
3. Water, Sodium and Potassium
4. Hydrogen Ion Homoeostasis and Blood Gases
5. The Kidneys
6. The Liver
7. The Gastrointestinal Tract
8. Clinical Nutrition
9. The Hypothalamus and the Pituitary Gland
10. The Adrenal Glands
11. The Thyroid Gland
12. The Gonads
13. Disorders of Carbohydrate Metabolism
14. Calcium, Phosphate and Magnesium
15. Bones and Joints
16. Plasma Proteins and Enzymes
17 Lipids, Lipoproteins and Cardiovascular Disease
18. Muscles, Nerves and Psychiatric?Disorders
19. Inherited Metabolic Diseases
20. Disorders of Haemoproteins, Porphyrins and Iron
21. Metabolic Aspects of Malignant Disease
22. Therapeutic Drug Monitoring and Chemical Aspects of Toxicology
23. Clinical Chemistry at the Extremes of Age
William J. Marshall, MA, PhD, MSc, MBBS, FRCP, FRCPath, FRCPEdin, FRSB, FRSC, Emeritus Reader in Clinical Biochemistry, Kings College London, London, UK; formerly Consultant Clinical Biochemist and Clinical Director of Pathology, The London Clinic, London, UK., Márta Lapsley, MB BCh BAO, MD, FRCPath, Consultant Chemical Pathologist, Epsom and St. Helier University Hospitals NHS Trust, Epsom, Surrey, UK, Andrew Day, MA MSc MBBS FRCPath, Consultant in Clinical Biochemistry and Metabolic Medicine, University Hospitals Bristol NHS Foundation Trust, Bristol, UK and Kate Shipman