A masterful introduction to the cell biology that you need to know! This critically acclaimed textbook offers you a modern and unique approach to the study of cell biology. It emphasizes that cellular structure, function, and dysfunction ultimately result from specific macromolecular interactions. You'll progress from an explanation of the "hardware" of molecules and cells to an understanding of how these structures function in the organism in both healthy and diseased states. The exquisite art program helps you to better visualize molecular structures.
- Covers essential concepts in a more efficient, reader-friendly manner than most other texts on this subject.
- Makes cell biology easier to understand by demonstrating how cellular structure, function, and dysfunction result from specific macromole¬cular interactions.
- Progresses logically from an explanation of the "hardware" of molecules and cells to an understanding of how these structures function in the organism in both healthy and diseased states.
- Helps you to visualize molecular structures and functions with over 1500 remarkable full-color illustrations that present physical structures to scale.
- Explains how molecular and cellular structures evolved in different organisms.
- Shows how molecular changes lead to the development of diseases through numerous Clinical Examples throughout.
- Includes STUDENT CONSULT access at no additional charge, enabling you to consult the textbook online, anywhere you go · perform quick searches · add your own notes and bookmarks · follow Integration Links to related bonus content from other STUDENT CONSULT titles—to help you see the connections between diverse disciplines · test your knowledge with multiple-choice review questions · and more!
- New keystone chapter on the origin and evolution of life on earth probably the best explanation of evolution for cell biologists available!
- Spectacular new artwork by gifted artist Graham Johnson of the Scripps Research Institute in San Diego. 200 new and 500 revised figures bring his keen insight to Cell Biology illustration and further aid the reader’s understanding.
- New chapters and sections on the most dynamic areas of cell biology - Organelles and membrane traffic by Jennifer Lippincott-Schwartz; RNA processing (including RNAi) by David Tollervey., updates on stem cells and DNA Repair.
- ,More readable than ever. Improved organization and an accessible new design increase the focus on understanding concepts and mechanisms.
- New guide to figures featuring specific organisms and specialized cells paired with a list of all of the figures showing these organisms. Permits easy review of cellular and molecular mechanisms.
- New glossary with one-stop definitions of over 1000 of the most important terms in cell biology.
SECTION I: Introduction to Cell Biology
Introduction to Cells
Evolution of Life on Earth
SECTION II: Chemical and Physical Background
Molecules: Structures and Dynamics
SECTION III: Membrane Structure and Function
Membrane Structure and Dynamics
SECTION IV: Chromatin, Chromosomes, and the Cell Nucleus
DNA Packaging in Chromatin and Chromosomes
Nuclear Structure and Dynamics
SECTION V: Central Dogma: From Gene to Protein
This chapter was written by Jeffrey L. Corden
Eukaryotic RNA Processing
This chapter was written by David Tollervey
Protein Synthesis and Folding
SECTION VI: Cellular Organelles and Membrane Trafficking
Posttranslational Targeting of Proteins
Mitochondria, Chloroplasts, Peroxisomes
Secretory Membrane System and Golgi Apparatus CHAPTER 22
Endocytosis and the Endosomal Membrane System CHAPTER 23
Degradation of Cellular Components
Plasma Membrane Receptors
Protein Hardware for Signaling
Integration of Signals
SECTION VIII: Cellular Adhesion and the Extracellular Matrix
Cells of the Extracellular Matrix and Immune System
Extracelluar Matrix Molecules
SECTION IX: Cytoskeleton and Cellular Motility
Actin and Actin-Binding Proteins
Microtubules and Centrosomes
SECTION X: Cell Cycle
Introduction to the Cell Cycle
G1 Phase and Regulation of Cell Proliferation
S Phase and DNA Replication
G2 Phase and Control of Entry into Mitosis
Mitosis and Cytokinesis
Programmed Cell Death