Featuring hundreds of full-color photomicrographs, Hematology: Clinical Principles and Applications prepares you for a job in the clinical lab by exploring the essential aspects of hematology. It shows how to accurately identify cells, simplifies hemostasis and thrombosis concepts, and covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins. This book also makes it easy to understand complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics. Well-known authors Bernadette Rodak, George Fritsma, and Elaine Keohane cover everything from working in a hematology lab to the parts and functions of the cell to laboratory testing of blood cells and body fluid cells.
Part I: Introduction to Hematology 1. An Overview of Clinical Laboratory Hematology 2. Safety in the Hematology Laboratory 3. Specimen Collection 4. Care and Use of the Microscope 5. Quality Assurance in Hematology and Hemostasis Testing Part II: Hematopoiesis and Blood Cell Physiology 6. Cellular Structure and Function 7. Hematopoiesis 8. Erythrocyte Production and Destruction 9. Energy Metabolism and Membrane Physiology of the Erythrocyte 10. Hemoglobin Metabolism 11. Iron Metabolism 12. Leukocyte Development, Kinetics, and Function 13. Platelet Production, Structure, and Function Part III: Routine Laboratory Evaluation of Blood Cells 14. Routine and Point of Care Testing in Hematology: Manual and Semi-Automated Methods 15. Examination of the Peripheral Blood Film and Correlation with the Complete Blood Count 16. Bone Marrow Collection and Examination 17. Hematologic Body Fluid Examination Part IV: Hematopathology: Erythrocyte Disorders 18. Anemias: Red Blood Cell Morphology and Approach to Diagnosis 19. Disorders of Iron and Heme Metabolism 20. Anemias Caused by Defects of DNA Metabolism 21. Bone Marrow Failure 22. Introduction to Increased Erythrocyte Destruction 23. Intrinsic Defects Leading to Increased Erythrocyte Destruction 24. Extrinsic Defects Leading to Increased Erythrocyte Destruction-- Nonimmune Causes 25. Extrinsic Defects Leading to Increased Erythrocyte Destruction-- Immune Causes 26. Hemoglobinopathies: Structural Hemoglobin Defects 27. Thalassemias: Quantitative Hemoglobin Defects Part V: Leukocyte Disorders 28. Non-Malignant Leukocyte Disorders 29. Introduction to Leukocyte Neoplasms 30. Cytochemistry 31. Cytogenetics 32. Molecular Diagnostics in the Hematology Laboratory 33. Flow Cytometric Analysis of Hematologic Disorders 34. Myeloproliferative Disorders 35. Myelodysplastic Syndromes 36. Acute Leukemias 37. Lymphomas and Chronic Lymphocytic Leukemias Part VI: Hematology in Selected Populations 38. Pediatric and Geriatric Hematology Part VII: Cell Counting Automation 39. Automated Cell Counting Instrumentation Part VIII: Hemostasis and Thrombosis 40. Normal Hemostasis and Coagulation 41. Hemorrhagic Coagulation Disorders 42. Thrombosis Risk Testing 43. Thrombocytopenia and Thrombocytosis 44. Qualitative Disorders of Platelets and Vasculature 45. Laboratory Evaluation of Hemostasis 46. Monitoring Anticoagulant Therapy 47. Coagulation Instrumentation