Pathophysiology, 5th Edition

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Pathophysiology, 5th Edition


A clear, comprehensive introduction to disease, Pathophysiology, 5th Edition explores the etiology, pathogenesis, clinical manifestations, and treatment of disorders. Units are organized by body system, and each begins with an illustrated review of anatomy and normal physiology. A discussion then follows on the disease processes and abnormalities that may occur, with a focus on the pathophysiologic concepts involved. Written by leading educators Lee-Ellen Copstead and Jacquelyn Banasik, Pathophysiology simplifies a rigorous subject with practical learning resources and includes coverage of the latest scientific findings and relevant research

    • 900 full-color illustrations clarify complex pathophysiological concepts.
    • Easy-to-read style includes many tables, boxes, and figures to highlight and simplify content.
    • Key Questions at the beginning of each chapter highlight key objectives and help you develop and use critical thinking skills.
    • Key Points boxes focus on the most important information.
    • Geriatric Considerations boxes analyze the age-related changes associated with a specific body system.
    • A chapter summary gives you a quick wrap-up of the key content in each chapter.
      • NEW! Pediatric Considerations boxes with accompanying flow charts describe conditions and changes specific to young children.
      • NEW! Updated content includes the latest information on new treatment advances, the relationship between stress and inflammation to cardiovascular disease, and much more throughout the text.
      • NEW! Global Health Considerations tables include information on HIV/AIDS and depression/anxiety in women.

        Unit I: Pathophysiologic Processes

        1. Introduction to Pathophysiology

        2. Homeostasis and Adaptive Responses to Stressors

        Unit II: Cellular Function

        3. Cell Structure and Function

        4. Cell Injury, Aging, and Death

        5. Genome Structure, Regulation, and Tissue Differentiation

        6. Genetic and Developmental Disorders

        7. Neoplasia

        Unit III: Defense

        8. Infectious Processes

        9. Inflammation and Immunity

        10. Alterations in Immune Function

        11. Malignant Disorders of White Blood Cells

        12. HIV Disease and AIDS

        Unit IV: Oxygen Transport, Blood Coagulation, Blood Flow, and Blood Pressure

        13. Alterations in Oxygen Transport

        14. Alterations in Homeostasis and Blood Coagulation

        15. Alterations in Blood Flow

        16. Alterations in Blood Pressure

        Unit V: Cardiac Function

        17. Cardiac Function

        18. Alterations in Cardiac Function

        19. Heart Failure and Dysrhythmias: Common Sequelae of Cardiac Diseases

        20. Shock

        Unit VI: Respiratory Function

        21. Respiratory Function and Alterations in Gas Exchange

        22. Obstructive Pulmonary Disorders

        23. Restrictive Pulmonary Disorders

        Unit VII: Fluid, Electrolyte, and Acid-Base Homeostasis

        24. Fluid and Electrolyte Homeostasis and Imbalances

        25. Acid-Base Homeostasis and Imbalances

        Unit VIII: Renal and Bladder Function

        26. Renal Function

        27. Intrarenal Disorders

        28. Acute Kidney Injury and Chronic Kidney Disease

        29. Disorders of the Lower Urinary Tract

        Unit IX: Genital and Reproductive Function

        30. Male Genital and Reproductive Function

        31. Alterations in Male Genital and Reproductive Function

        32. Female Genital and Reproductive Function

        33. Alterations in Female Genital and Reproductive Function

        34. Sexually Transmitted Infections

        Unit X: Gastrointestinal Function

        35. Gastrointestinal Function

        36. Gastrointestinal Disorders

        37. Alterations in Function of the Gallbladder and Exocrine Pancreas

        38. Liver Diseases

        Unit XI: Endocrine Function, Metabolism, and Nutrition

        39. Endocrine Physiology and Mechanisms of Hypothalamic-Pituitary Regulation

        40. Disorders of Endocrine Function

        41. Diabetes Mellitus

        42. Alterations in Metabolism and Nutrition

        Unit XII: Neural Function

        43. Structure and Function of the Nervous System

        44. Acute Disorders of Brain Function

        45. Chronic Disorders of Neurologic Function

        46. Alterations in Special Sensory Function

        47. Pain

        Unit XIII: Neuropsychological Function

        48. Neurobiology of Psychotic Illnesses

        49. Neurobiology of Nonpsychotic Illnesses

        Unit XIV: Musculoskeletal Support and Movement

        50. Structure and Function of the Musculoskeletal System

        51. Alterations in Musculoskeletal Function: Trauma, Infection, and Disease

        52. Alterations in Musculoskeletal Function: Rheumatic Disorders

        Unit XV: Integumentary System

        53. Alterations in the Integumentary System

        54. Burn Injuries

        Appendix: Clinical and Laboratory Values

        Lee-Ellen C. Copstead-Kirkhorn, PhD, RN, Professor and Chair of Nursing, Department of Nursing, College of Nursing and Health Sciences, Indiana University -Purdue University, IPFW --Fort Wayne, Fort Wayne, IN and Jacquelyn L. Banasik, PhD, ARNP, Associate Professor, WSU Intercollegiate College of Nursing, Washington State University, Spokane, WA


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