Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 7th Edition
A condensed, easier-to-understand student version of the acclaimed Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 7th Edition uses a laboratory perspective in providing the clinical chemistry fundamentals you need to work in a real-world, clinical lab. Coverage ranges from laboratory principles to analytical techniques and instrumentation, analytes, pathophysiology, and more. New content keeps you current with the latest developments in molecular diagnostics. From highly respected clinical chemistry experts Carl Burtis and David Bruns, this textbook shows how to select and perform diagnostic lab tests, and accurately evaluate results.
- Authoritative, respected author team consists of two well-known experts in the clinical chemistry world.
- Coverage of analytical techniques and instrumentation includes optical techniques, electrochemistry, electrophoresis, chromatography, mass spectrometry, enzymology, immunochemical techniques, microchips, automation, and point of care testing.
- Learning objectives begin each chapter, providing measurable outcomes to achieve after completing the material.
- Key words are listed and defined at the beginning of each chapter, and bolded in the text.
- A glossary at the end of the book makes it quick and easy to look up definitions of key terms.
- More than 500 illustrations plus easy-to-read tables help you understand and remember key concepts.
- New chapters on molecular diagnostics include the principles of molecular biology, nucleic acid techniques and applications, and genomes and nucleic acid alterations, reflecting the changes in this rapidly evolving field.
- New content on clinical evaluation of methods, kidney function tests, and diabetes is added to this edition.
- NEW multiple-choice review questions at the end of each chapter allow you to measure your comprehension of the material.
- NEW case studies on the Evolve companion website use real-life scenarios to reinforce concepts.
I. PRINCIPLES OF LABORATORY MEDICINE
1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
3. Clinical Evaluation of Methods
4. Evidence-Based Laboratory Medicine
5. Establishment and Use of Reference Values
6. Specimen Collection, Processing, and Other Preanalytical Variables
7. Quality Management
II. ANALYTICAL TECHNIQUES AND INSTRUMENTATION
8. Principles of Basic Techniques and Laboratory Safety
9. Optical Techniques
10. Electrochemistry and Chemical Sensors
13. Mass Spectrometry
14. Enzyme and Rate Analyses
15. Immunochemical Techniques
17. Point-of-Care Instrumentation
18. Amino Acids, Peptides, and Proteins
19. Serum Enzymes
20. Tumor Markers and Cancer Genes
21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
24. Electrolytes and Blood Gases
26. Catecholamines and Serotonin
27. Vitamins, Trace Elements, Nutritional Assessment
28. Hemoglobin, Iron, and Bilirubin
29. Porphyrins and Porphyrias
30. Therapeutic Drugs and Their Management
31. Clinical Toxicology
32. Toxic Metals
34. Cardiovascular Disease
35. Kidney Disease
36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
37. Liver Disease
38. Gastrointestinal and Pancreatic Diseases
39. Disorders of Bone and Mineral Metabolism
40. Disorders of the Pituitary Gland
41. Disorders of the Adrenal Cortex
42. Thyroid Disorders
43. Reproduction-Related Disorders
44. Pregnancy and Prenatal Testing
45. Newborn Screening and Inborn Errors of Metabolism
V. MOLECULAR DIAGNOSTICS NEW!
47. Principles of Molecular Biology
48. Nucleic Acid Techniques and Applications
49. Genomes and Nucleic Acid Alterations
VI. REFERENCE INFORMATION
50. Reference Information for the Clinical Laboratory
Carl A. Burtis, PhD, Health Services Division, Oak Ridge National Laboratory, Oak Ridge, TN, and Clinical Professor of Pathology, University of Utah School of Medicine, Salt Lake City, UT and David E. Bruns, MD, Professor of Pathology, University of Virginia School of Medicine, Director of Clinical Chemistry and Associate Director of Molecular Diagnostics, University of Virginia Health System, Charlottesville, VA, and Former Editor, Clinical Chemistry, Washington, DC