The much-anticipated 3rd edition of Cell Biology delivers comprehensive, clearly written, and richly illustrated content to today’s students, all in a user-friendly format. Relevant to both research and clinical practice, this rich resource covers key principles of cellular function and uses them to explain how molecular defects lead to cellular dysfunction and cause human disease. Concise text and visually amazing graphics simplify complex information and help readers make the most of their study time.
Student Consult eBook version included with purchase.
Evolve Instructor Resources, including a downloadableimage and test bank, are available to instructors through their Elsevier sales rep or via request at: https://evolve.elsevier.com
New didactic chapter flow is more oriented toward teaching.
Clearly written format incorporates rich illustrations, diagrams, and charts.
Uses real examples to illustrate key cell biology concepts.
Includes beneficial cell physiology coverage.
Clinically oriented text relates cell biology to pathophysiology and medicine.
Takes a mechanistic approach to molecular processes.
Section 1: Introduction to Cell Biology 1. Introduction to Cells 2. Evolution of Life on Earth
Section 2: Chemical and Physical Background 3. Molecules: Structures and Dynamics 4. Biophysical Principles 5. Macromolecular Assembly 6. Research Strategies
Section 3: Chromatin, Chromosomes, and the Cell Nucleus 7. Chromosome Organization 8. DNA Packaging in Chromatin and Chromosomes 9. Nuclear Structure and Dynamics
Section 4: Central Dogma: From Gene to Protein 10. Gene Expression 11. Eukaryotic RNA Processing 12. Protein Synthesis and Folding
Section 5: Membrane Structure and Function 13. Membrane Structure and Dynamics 14. Membrane Pumps 15. Membrane Carriers 16. Membrane Channels 17. Membrane Physiology
Section 6: Cellular Organelles and Membrane Trafficking 18. Posttranslational Targeting of Proteins 19. Mitochondria, Chloroplasts, Peroxisomes 20. Endoplasmic Reticulum 21. Secretory Membrane System and Golgi Apparatus 22. Endocytosis and the Endosomal Membrane 23. Processing and Degradation of Cellular Components
Section 7: Signaling Mechanisms 24. Plasma Membrane Receptors 25. Protein Hardware for Signaling 26. Second Messengers 27. Integration of Signals
Section 8: Cellular Adhesion and the Extracellular Matrix 28. Cells of the Extracellular Matrix and Immune System 29. Extracellular Matrix Molecules 30. Cellular Adhesion 31. Intercellular Junctions 32. Connective Tissues
Section 9: Cytoskeleton and Cellular Motility 33. Actin and Actin-Binding Proteins 34. Microtubules and Centrosomes 35. Intermediate Filaments 36. Motor Proteins 37. Intracellular Motility 38. Cellular Motility 39. Muscles
Section 10: Cell Cycle 40. Introduction to the Cell Cycle 41. G1 Phase and Regulation of Cell Proliferation 42. S Phase and DNA Replication 43. G2 Phase and Control of Entry into Mitosis 44. Mitosis and Cytokinesis 45. Meiosis 46. Programmed Cell Death
Thomas D. Pollard, MD, Sterling Professor, Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT, USA, William C. Earnshaw, PhD, FRS, Professor and Wellcome Trust Principal Research Fellow, Wellcome Trust Centre for Cell Biology, ICB, University of Edinburgh, Scotland, UK, Jennifer Lippincott-Schwartz, PhD, Group Leader, Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, Virginia, USA and Graham Johnson, MA, PhD, CMI, Director, Animated Cell, Allen Institute for Cell Biology, Seattle, Washington;, QB3 Faculty Fellow, University of California, San Francisco, San Francisco, California, USA
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