cover image - Stroke, 7th Edition
ISBN: 9780323694247
Copyright: 2022
Publication Date: 03-03-2021
Page Count: 1176
Imprint: Elsevier
List Price: $315.99

Stroke, 7th Edition

by James C. Grotta, MD, Gregory W. Albers, MD, Joseph P. Broderick, MD, Scott E. Kasner, MD, MSCE, FRCP, Eng H. Lo, PhD, Ralph L Sacco, MD MS FAHA FAAN, Lawrence KS Wong, MD, FRCP and Arthur L. Day

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cover image - Stroke, 7th Edition
ISBN: 9780323694247
Copyright: 2022
Publication Date: 03-03-2021
Page Count: 1176
Imprint: Elsevier
List Price: $315.99
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Authored by the world’s foremost stroke experts, this classic text brings you fully up to date with current research findings and management approaches for cerebrovascular disease. Stroke: Pathophysiology, Diagnosis, and Management, 7th Edition, covers every aspect of this fast-moving field, and is an ideal resource for stroke specialists, general neurologists, and other medical professionals with an interest in stroke. You’ll find expert clinical guidance, comprehensive pathophysiology coverage, data from recent trials, advances in diagnostic tests, full-color CT images, pathology slides, and much more, for a complete picture of today’s stroke medicine.
    • Helps you recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan
    • Keeps you abreast of the overwhelming volume of studies and guidelines in this dynamic field, providing clear summaries and practical evaluations of all relevant data
    • Contains updates throughout, including the latest clinical trials (thrombectomy, DAWN, DEFUSE), genetics research, prevention research, new therapies, and the new guidelines from the ASA
    • Includes new slides for lectures, covering basic science, case studies, and interventional treatment overviews
    • Features a Key Points summary at the beginning of each chapter so you can quickly find important information
    • Provides abundant full-color CT images and pathology slides that help you make efficient and accurate diagnoses
    • Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices

  • Section 1 Pathophysiology
    1. Cerebral Vascular Biology in Health and Disease
    2. Mechanisms of Thrombosis and Thrombolysis
    3. Cerebral Blood Flow and Metabolism: Regulation and Pathophysiology in Cerebrovascular Disease
    4. Histopathology of Brain Tissue Response to Stroke and Injury
    5. Molecular and Cellular Mechanisms of Ischemia-Induced Neuronal Death
    6. Intracellular Signaling: Mediators and Protective Responses
    7. The Neurovascular Unit and Responses to Ischemia
    8. Mechanisms of Damage After Cerebral Hemorrhage
    9. White Matter Pathophysiology
    10. Cerebral Ischemia and Inflammation
    11. Mechanisms of Plasticity, Remodeling and Recovery
    12. Genetics and Vascular Biology of Brain Vascular Malformations
    13. Gliovascular Mechanisms and White Matter Injury in Vascular Cognitive Impairment and Dementia

    Section 2 Epidemiology and Risk Factors
    14. Global Burden of Stroke
    15. Stroke Disparities
    16. Risk Factors and Prevention
    17. Prognosis after Stroke
    18. Vascular Dementia and Cognitive Impairment
    19. Genetic Basis of Stroke Occurrence, Prevention and Outcome

    Section 3 Clinical Manifestations
    20. Classification of Ischemic Stroke
    21. Clinical Scales to Assess Patients with Stroke
    22. Carotid Artery Disease
    23. Anterior Cerebral Artery Disease
    24. Middle Cerebral Artery Disease
    25. Posterior Cerebral Artery Disease
    26. Vertebrobasilar Disease
    27. Lacunar Syndromes, Lacunar Infarcts, and Cerebral Small-Vessel Disease
    28. Intracerebral Hemorrhage
    29. Aneurysmal Subarachnoid Hemorrhage
    30. Arteriovenous Malformations and Other Vascular Anomalies
    31. Stroke and Other Vascular Syndromes of the Spinal Cord

    Section 4 Specific Conditions and Stroke
    32. Cardiac Diseases
    33. Atherosclerotic Disease of the Proximal Aorta
    34. Stroke Related to Surgery and Other Procedures
    35. Arterial Dissection, Fibromuscular Dysplasia, and Carotid Web
    36. Inflammatory and Infectious Vasculopathies
    37. Reversible Cerebral Vasoconstriction Syndromes
    38. Posterior Reversible Encephalopathy Syndrome
    39. Stroke and Substance Abuse
    40. Moyamoya Disease
    41. Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
    42. Hematologic Disorders and Stroke
    43. Migraine and Stroke
    44. Cryptogenic Stroke
    45. Cerebral Venous Thrombosis

    Section 5 Diagnostic Studies
    46. Ultrasonography
    47. Computed Tomography-Based Evaluation of Cerebrovascular Disease
    48. Magnetic Resonance Imaging of Cerebrovascular Diseases
    49. Cerebral Angiography
    50. OMICs in Stroke: Insight into stroke through epigenomics, transcriptomics, proteomics, lipidomics, and metabolomics

    Section 6 Therapy
    Part A: Medical Therapy
    51. Stroke Systems of Care and Impact on Acute Stroke Treatment
    52. Prehospital and Emergency Department Care of the Patient with Acute Stroke
    53. Intravenous Thrombolysis
    54. Antithrombotic Therapy for Treatment of Acute Ischemic Stroke
    55. General Stroke Management and Stroke Units
    56. Critical Care of the Patient with Acute Stroke, 
    57. Pharmacologic Modification of Acute Cerebral Ischemia
    58. Treatment of "Other" Stroke Etiologies
    59. Medical Therapy of Intracerebral and Intraventricular Hemorrhage
    60. Rehabilitation and Recovery of the Patient with Stroke
    61. Interventions to Improve Recovery after Stroke
    62. Enhancing Stroke Recovery with Cellular Therapies
    63. Antiplatelet Therapy for Secondary Prevention of Stroke
    64. Secondary Prevention of Cardioembolic Stroke
    65. Design of Stroke-Related Clinical Trials
    Part B: Interventional Therapy
    66. Endovascular Therapy of Extracranial and Intracranial Occlusive Disease
    67. Endovascular Treatment of Acute Ischemic Stroke
    68. Endovascular Treatment of Intracranial Aneurysms
    69. Interventional Therapy of Brain and Spinal Arteriovenous Malformations
    70. Dural Arteriovenous Malformations
    Part C: Surgical Therapy
    71. Surgery of Anterior and Posterior Aneurysms
    72. Surgery for Intracerebral Hemorrhage
    73. Management of Intraventricular Hemorrhage
    74. Surgical Management of Cranial and Spinal Arteriovenous Malformations
    75. Surgical Management of Cavernous Malformations and Venous Anomalies
    76. Indications for Carotid Endarterectomy in Patients with Asymptomatic and Symptomatic Carotid Stenosis
    77. Extracranial to Intracranial Bypass for Cerebral Ischemia
    78. Decompressive Craniectomy for Infarction and Hemorrhage

  • James C. Grotta, MD, Director, Stroke Program, Memorial Hermann - Texas Medical Center; Professor of Neurology; Chairman, Department of Neurology, University of Texas Medical School at Houston, Houston, TX, USA, Gregory W. Albers, MD, Director, Stanford Stroke Center; Coyote Foundation Professor of Neurology and Neurological Sciences, USA, Joseph P. Broderick, MD, Director of the Greater Cincinnati-Northern Kentucky Stroke Team; Professor and Chairman, University of Cincinnati, Department of Neurology and Rehabilitation Medicine, Cincinnati, OH, USA, Scott E. Kasner, MD, MSCE, FRCP, Professor of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA, Eng H. Lo, PhD, Professor of Neurology and Radiology, Harvard Medical School, Research Staff, Mass General Hospital, Massachusetts General Hospital, Neuroprotection Research Lab, Charlestown, MA, USA, Ralph L Sacco, MD MS FAHA FAAN, Olemberg Chair of Neurology and Professor of Neurology, Epidemiology and Public Health, Human Genetics, and Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, Lawrence KS Wong, MD, FRCP, Mok Hing Yiu Professor of Medicine, Chief of Neurology, Departments of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, PR China and Arthur L. Day