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cover image - Diagnostic Pathology: Neuropathology,3rd Edition
ISBN: 9780323713306
Publication Date: 01-20-2022
Page Count: 900
Imprint: Elsevier
List Price: $315.99

Diagnostic Pathology: Neuropathology, 3rd Edition

by B.K. Kleinschmidt-DeMasters, MD, Melike Pekmezci, MD, Fausto Rodriguez, MD and Tarik Tihan, MD, PhD


cover image - Diagnostic Pathology: Neuropathology,3rd Edition
ISBN: 9780323713306
Publication Date: 01-20-2022
Page Count: 900
Imprint: Elsevier
    • Incorporates new WHO Classification of Tumors of the Central Nervous System, 5th Edition

    • Offers information on neoplasms of the brain, sellar region, and peripheral nerves, as well as benign cysts and selected infectious, inflammatory, reactive, and vascular lesions, aiding you in arriving at the correct diagnosis

    • Emphasizes surgical pathology but also provides significant content on nonneoplastic diseases that present with focal lesions, especially those that are potentially misinterpreted as neoplasms

    • Features new and updated chapters detailing several types of tumors that have been reclassified due to recent molecular driver information, cIMPACT-NOW recommendations, and the WHO Classification, 5th Edition

    • Features nearly 1,700 annotated images throughout, including neuroimaging studies, histology and immunohistochemical stains, and high-quality medical illustrations

    • Incorporates time-saving features such as a templated, highly formatted design; concise, bulleted text; a variety of test data tables; key facts in each chapter; and an extensive index

    • Includes the enhanced eBook version, which allows you to access all text, figures, and references on a variety of devices
  • Neoplastic

    Brain and Spinal Cord

    Diffuse Astrocytic and Oligodendroglial Tumors

    Diffuse Astrocytoma, IDH-Mutant, WHO Grade II

    Diffuse Astrocytoma, IDH-Wildtype, WHO Grade II (Provisional Entity)

    Anaplastic Astrocytoma, IDH-Mutant, WHO Grade III

    Anaplastic Astrocytoma, IDH-Wildtype, WHO Grade III

    Glioblastoma, IDH-Wildtype

    Granular Cell Astrocytoma of the Cerebrum


    Glioblastoma, IDH Mutant

    Diffuse Midline Glioma, H3 K27M Mutant

    H3 G34-Mutant Gliomas, IDH-Wildtype (Provisional Entity)


    Anaplastic Oligodendroglioma

    Mixed Oligoastrocytoma

    Other Astrocytic Tumors

    Pilocytic Astrocytoma

    Pilomyxoid Astrocytoma

    Subependymal Giant Cell Astrocytoma

    Pleomorphic Xanthoastrocytoma

    Anaplastic Pleomorphic Xanthoastrocytoma

    Pediatric Low-Grade Glioma/Glioneuronal Tumors (Provisional Entities)

    Ependymal Tumors


    Myxopapillary Ependymoma


    Ependymoma, *RELA* Fusion-Positive

    Anaplastic Ependymoma

    Other Gliomas

    Chordoid Glioma of 3rd Ventricle

    Angiocentric Glioma


    Choroid Plexus Tumors

    Choroid Plexus Papilloma and Atypical Papilloma

    Choroid Plexus Carcinoma

    Neuronal and Mixed Neuronal-Glial Tumors

    Dysembryoplastic Neuroepithelial Tumor

    Gangliocytoma and Ganglioglioma

    Dysplastic Cerebellar Gangliocytoma (Lhermitte-Duclos Disease)

    Desmoplastic Infantile Ganglioglioma

    Papillary Glioneuronal Tumor

    Rosette-Forming Glioneuronal Tumor of 4th Ventricle

    Diffuse Leptomeningeal Glioneuronal Tumor

    Malignant Glioneuronal Tumors

    Central Neurocytoma

    Extraventricular Neurocytoma

    Cerebellar Liponeurocytoma

    Paraganglioma of Filum Terminale

    Tumors of the Pineal Region

    Pineal Parenchymal Neoplasms

    Papillary Tumor of the Pineal Region

    Pineal Anlage Tumor

    Embryonal Tumors


    CNS Embryonal Neoplasms

    Embryonal Tumor With Multilayered Rosettes, C19MC Altered

    Ewing Sarcoma

    Atypical Teratoid/Rhabdoid Tumor

    Germ Cell Tumors



    Other Germ Cell Tumors

    Lymphomas and Histiocytic Tumors

    Primary Central Nervous System Lymphoma

    Lymphomatosis Cerebri

    Lymphomatoid Granulomatosis

    Intravascular Lymphomatosis

    Primary Amyloidoma

    Langerhans Cell Histiocytosis

    Erdheim-Chester Disease

    Rosai-Dorfman Disease

    Metastatic Tumors

    Metastatic Neoplasms, Intraparenchymal, Brain and Spinal Cord

    Sellar Region

    Adenohypophyseal Neoplasia and Hyperplasia

    Pituitary Adenoma


    Somatotroph Adenoma

    Corticotroph Adenoma

    Gonadotroph Adenoma

    Thyrotroph Adenoma

    Plurihormonal Adenoma

    Null Cell Adenoma

    Pituitary Hyperplasia

    Pituitary Carcinoma

    TTF-Mediated Neurohypophyseal Neoplasms

    Granular Cell Tumor of the Sellar Region


    Spindle Cell Oncocytoma


    Adamantinomatous Craniopharyngioma

    Papillary Craniopharyngioma

    Miscellaneous Neoplasms

    Pituitary Blastoma

    Secondary Neoplasms of the Pituitary and Sellar Region

    Hypothalamic Hamartoma

    Meningiomas and Mesenchymal Nonmeningothelial Tumors


    Solitary Fibrous Tumor/Hemangiopericytoma


    Primary Melanocytic Neoplasms

    Osteocartilaginous Neoplasms

    Notochordal Tumors


    Smooth Muscle Neoplasms

    Adipocytic Neoplasms

    Meningeal Glioma and Gliomatosis

    Metastatic Neoplasms, Intracranial and Intraspinal Meninges

    Tumors of Cranial and Paraspinal Nerves

    Schwannoma Variants

    Conventional Schwannoma

    Cellular Schwannoma

    Plexiform Schwannoma

    Melanotic Schwannoma


    Plexiform Neurofibroma

    Localized Intraneural Neurofibroma

    Extraneural Neurofibroma Variants


    Intraneural Perineurioma

    Soft Tissue Perineurioma

    Primary Malignant Neoplasms of Nerve

    Malignant Peripheral Nerve Sheath Tumor

    Lipoma of 8th Cranial Nerve

    Lipoma of 8th Cranial Nerve

    Familial Tumor Syndromes


    Neurofibromatosis 1

    Neurofibromatosis 2



    von Hippel-Lindau Syndrome

    Tuberous Sclerosis Complex

    Turcot Syndrome


    Benign Cysts

    Arachnoid Cyst

    Epidermoid and Dermoid Cysts

    Colloid Cyst

    Rathke Cleft Cyst

    Endodermal Cyst

    Ependymal Cyst

    Pineal Cyst

    Facet Joint Synovial Cyst

    Infectious, Inflammatory, and Reactive Lesions

    Demyelinating Diseases

    Demyelinating Disease (Multiple Sclerosis-Tumefactive Demyelination)

    Bacterial Infections

    Abscess and Cerebritis

    Whipple Disease


    Viral Infections

    Herpes Simplex Encephalitis

    Progressive Multifocal Leukoencephalopathy

    HIV Encephalitis

    Other Viral Infections

    Fungal Infections

    Fungal Infections

    Protozoal and Parasitic Infections




    Miscellaneous Parasitic Infections

    Other Inflammatory Diseases


    Rasmussen Encephalitis

    Paraneoplastic Disease

    Textiloma (Muslinoma, Gauzoma, Gossypiboma)

    Inflammatory Pseudotumors

    Lymphocytic Hypophysitis

    Reactive Conditions and Noninflammatory Pseudoneoplasms


    Meningeal Response to Intracranial Hypotension

    Radiation Necrosis

    Calcifying Pseudoneoplasm of the Neuraxis

    Vascular Diseases

    Vascular Malformations and Neopla

  • B.K. Kleinschmidt-DeMasters, MD, Professor of Pathology, Neurology, and Neurosurgery, Director of Neuropathology, University of Colorado School of Medicine, Aurora, Colorado, Melike Pekmezci, MD, Melike Pekmezci, MD, Associate Professor of Pathology and Ophthalmology, Department of Pathology and Ophthalmology, University of California, San Francisco; Staff Pathologist, San Francisco Veterans Affairs Medical Center, San Francisco, California, Fausto Rodriguez, MD, Professor and Chief of Neuropathology, David Geffen School of Medicine, Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, California and Tarik Tihan, MD, PhD, Professor of Pathology, Neuropathology Division, University of California San Francisco School of Medicine, San Francisco, California