Tietz Textbook of Laboratory Medicine - Elsevier eBook on VitalSource, 7th Edition
Elsevier eBook on VitalSource
Choose THE definitive reference for laboratory medicine and clinical pathology! Tietz Textbook of Laboratory Medicine, 7th Edition provides the guidance necessary to select, perform, and evaluate the results of new and established laboratory tests. Comprehensive coverage includes the latest advances in topics such as clinical chemistry, genetic metabolic disorders, molecular diagnostics, hematology and coagulation, clinical microbiology, transfusion medicine, and clinical immunology. From a team of expert contributors led by Nader Rifai, this reference includes access to wide-ranging online resources on Expert Consult — featuring the comprehensive product with fully searchable text, regular content updates, animations, podcasts, over 1300 clinical case studies, more than 2500 multiple-choice questions, lecture series, and an additional 100+ adaptive learning courses.
- Authoritative, current content helps you perform tests in a cost-effective, timely, and efficient manner; provides expertise in managing clinical laboratory needs; and shows how to be responsive to an ever-changing environment.
- Current guidelines help you select, perform, and evaluate the results of new and established laboratory tests.
- Expert, internationally recognized chapter authors present guidelines representing different practices and points of view.
- Analytical criteria focus on the medical usefulness of laboratory procedures.
- Use of standard and international units of measure makes this text appropriate for any user, anywhere in the world.
- Expert Consult provides the entire text as a fully searchable eBook, and includes regular content updates, animations, podcasts, more than 1300 clinical case studies, over 2500 multiple-choice questions, a lecture series, and more.
- NEW! 19 additional chapters highlight various specialties throughout laboratory medicine.
- NEW! Updated, peer-reviewed content provides the most current information possible.
- NEW! The largest-ever compilation of clinical cases in laboratory medicine is included on Expert Consult.
- NEW! Over 100 adaptive learning courses on Expert Consult offer the opportunity for personalized education.
Note: Italicized chapters will appear online only via Expert Consult.
SECTION I: BASICS OF LABORATORY MEDICINE 1. Laboratory Medicine 2. Statistical Methodologies in Laboratory Medicine 3. Quality Management in the Clinical Laboratory 4. Specimen Collection and Handling 5. Preanalytical Variations & Preexamination Process 6. Quality Control 7. Standardization and Harmonization 8. Biological Variations 9. Reference Intervals 10. Evidenced-based Lab Medicine 11. Biobanking 12. Lab Support of Pharma, IVD and EPI Studies 13. Machine Learning and Big Data 14. Utilization of Laboratory Tests 15. Lab Safety SECTION II: ANAYLTICAL TECHNIQUES 16. Optical Techniques 17. Electrochemistry and Chemical Sensors 18. Electrophoresis 19. Chromatography 20. Mass spec 21. Sample Preparation for MS 22. MS Application in Infectious Disease 23. MS for Small Molecule 24. Proteomics 25. Enzyme and Rate Analysis 26. Immunochemical Techniques 27. Microfibrication and Microfluidics 28. Cytometry 29. Automation in the Clinical Lab 30. Point-of-Care Testing SECTION III: CLINICAL CHEMISTRY-ANALYTES 31. Amino Acids, Peptides, and Proteins 32. Serum Enzymes 33. Tumor Markers 34. Kidney Function Tests 35. Carbohydrates 36. Lipids and Lipoproteins 37. Electrolytes and Blood Gases 38. Hormone 39. Vitamins and Trace Elements 40. Iron Metabolism 41. Porphyrins and Porphyrias 42. TDM 43. Clinical Toxicology 44. Toxic Elements 45. Body Fluids SECTION IV: CLINICAL CHEMISTRY-PATHOPHYSIOLOGY 46. Nutrition 47. Diabetes Mellitus 48. Cardiac Function 49. Kidney Disease 50. Disorders of Water, Electrolytes, and Acid-Base Met 51. Liver Disease 52. Gastric, Pancreatic & Intestinal Function 53. Mono-amine Producing Tumor 54. Bone and Mineral Metabolism 55. Pituitary Function 56. Adrenal Cortex 57. Thyroid Disorders 58. Reproductive Endocrinology 59. Pregnancy and its Disorders SECTION V: GENETIC METABOLIC DISORDERS 60. Newborn Screening and IEM (Small Molecules) 61. Newborn Screening and IEM (Large Molecules) SECTION VI: MOLECULAR DIAGNOSTICS 62. Principles of Molecular Biology 63. Nucleic Acid Isolation 64. Nucleic Acid Techniques 65. Genomes, Variants, and Massively Paralleled Methods 66. Clinical Genome Sequencing 67. Molecular Microbiology 68. Genetics 69. Solid Tumors 70. Hematopathology 71. Circulating Tumor Cells & Circulating Nucleic Acids in Oncology 72. Circulating Nucleic Acids for Prenatal Diagnostics 73. Pharmacogenetics SECTION VII: HEMATOLOGY AND COAGULATION 74. Automated Hematology 75. WBC Morphology 76. RBC Morphology & Indices with Clinical Chemistry Interface 77. Hemoglobin & Hemoglobinopathies 78. Enzymes of the RBC 79. Physiology of Hemostasis 80. Platelets & von Willebrand Factor 81. Coagulation & Fibrinolysis SECTION VIII: MICROBIOLOGY 82. Overview of Infectious Disease 83. The Role of the Clinical Laboratory in Infection Prevention and Antimicrobial Stewardship 84. Bacteriology 85. Antimicrobial Susceptibility Testing 86. Mycobacteriology 87. Mycology 88. Parasitology 89. Virology SECTION IX: TRANSFUSION MEDICINE 90. Blood Groups and Pretransfusion Testing 91. Blood Components, Products Modifications, Blood Donor Screening 92. Indications for Transfusion: RBCs, Platelets, Plasma, and Cryoprecipitate 93. Transfusion Reactions/Adverse Events Associated with Transfusion SECTION X: CLINICAL IMMUNOLOGY 94. Systemic Autoimmune Disease (ANA testing, RF, CCP, antibodies, etc.) 95. Transplant, Solid Organ 96. Transplant, Bone Marrow 97. Immunogenetics 98. Therapeutic Monoclonal Antibodies and Immunogenicity 99. Allergy Testing 100. Primary and Secondary Immunodeficiencies APPENDIX Reference Information for the Clinical Laboratory Tietz Atlas of Biochemical Genetics: The Roy Peake Collection Tietz Atlas of Electrophoretic Patterns Tietz Clinical Vignettes: The Coakley Collection and Other Short Cases Tietz Biochemical Calculations: Deacon's Challenge Tietz Teasers in Parasitology: The Bobbit Pritt Collection Atlas of Parasitology: The Bobbi Pritt Collection
Nader Rifai, PhD, Professor Department of Pathology Harvard Medical School; The Louis Joseph Gay-Lussac Chair in Laboratory Medicine Boston Children's Hospital; Director of Clinical Chemistry Laboratory Medicine Boston Children's Hospital Boston, Massachusetts