cover image - Understanding Pathophysiology, 8th Edition
ISBN: 9780323937283
Copyright: 2026
Page Count: 1120
Imprint: Elsevier
List Price: $146.99

Understanding Pathophysiology, 8th Edition

by Sue E. Huether, MS, PhD, Kathryn L. McCance, MS, PhD and Valentina L. Brashers, MD, FACP, FNAP

Paperback

cover image - Understanding Pathophysiology, 8th Edition
ISBN: 9780323937283
Copyright: 2026
Page Count: 1120
Imprint: Elsevier
List Price: $146.99
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A review copy request is most likely to be fulfilled as an eBook on VitalSource rather than a print product, unless no eBook is available. eBooks become available in as little as a few hours. Print products will take between 7 and 10 days to arrive. To request a print copy, please contact us through the Evolve Support Center for further assistance or contact your Education Solutions Consultant.
Coming Soon!
Expected availability date: 02-03-2025
Important note
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Provide your students with in-depth knowledge of the concepts and processes of disease! Understanding Pathophysiology, 8th Edition provides a concise, comprehensive introduction to the way diseases work and how changes occur in the body as a result. With a clinically focused approach, the book begins by explaining cell structure and function. It then examines alterations by body systems and provides a practical guide to clinical manifestations, summaries of treatment, and health promotion strategies. This edition adds new algorithms, case studies for the Next-Generation NCLEX® Exam, and updated content on COVID-19, obesity, and cancer epidemiology. Ideal for nurses and other health professionals alike, this text helps students master important concepts and develop clinical judgment.
    • NEW! Case studies for the Next-Generation NCLEX® Exam (NGN) are provided on the Evolve website, helping students develop clinical judgment
    • NEW! Content updates address infectious disease, COVID-19 and post-COVID conditions, systemic pathophysiologic effects of obesity, cancer epidemiology, and more
    • NEW! Additional new algorithms show the pathophysiologic pathways and progression of disease
    • Consistent presentation of each disease includes pathophysiology, clinical manifestations, and evaluation and treatment
    • Lifespan content includes nine separate chapters with pediatric content and special sections on aging within the adult chapters, along with special boxes that highlight aging and pediatric content
    • More than 1000 images include photographs showing pathologic features of disease as well as micrographs showing normal and abnormal cellular structure
    • Risk Factor boxes show how certain risk factors are associated with specific diseases
    • Quick Check boxes appear at the end of major sections and are designed to help students recall the most important content
    • End-of-chapter Summary Reviews highlight the major concepts presented in each chapter
    • Did You Know boxes discuss new developments in biologic research, diagnostic studies, preventive care, treatments, and more
    • Key Terms are bolded, and listed with page numbers at the end of each chapter
    • Student resources on Evolve include animations, review questions, chapter summaries, and answers to the Quick Check questions
    • Instructor resources on Evolve include an image collection, TEACH lesson plans with case studies, PowerPoint® slides, NGN case studies, a conversion guide, and a test bank
  • PART ONE: BASIC CONCEPTS OF PATHOPHYSIOLOGY
    UNIT 1: The Cell
    1. Cellular Biology
    2. Genes and Genetic Diseases
    3. Epigenetics and Disease
    4. Altered Cellular and Tissue Biology
    5. Fluids and Electrolytes, Acids and Bases

    UNIT 2: Mechanisms of Self-Defense
    6. Innate Immunity: Inflammation and Wound Healing
    7. Adaptive Immunity
    8. Alterations in Immunity
    9. Infection
    10. Stress and Disease

    UNIT 3: Cellular Proliferation: Cancer
    11. Cancer Biology
    12. Cancer Epidemiology
    13. Cancer in Children and Adolescents

    PART TWO: BODY SYSTEMS AND DISEASES
    UNIT 4: The Neurologic System
    14. Structure and Function of the Neurologic System
    15. Pain, Temperature, Sleep, and Sensory Function
    16. Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function
    17. Alterations of the Brain, Spinal Cord and Peripheral Nerves
    18. Alterations of Neurologic Function in Children

    UNIT 5: The Endocrine System
    19. Mechanisms of Hormonal Regulation
    20. Alterations of Hormonal Regulation
    21. Obesity, Starvation, and Anorexia of Aging

    UNIT 6: The Hematologic System
    22. Structure and Function of the Hematologic System
    23. Alterations of Hematologic Function
    24. Alterations of Hematologic Function in Children

    UNIT 7: The Cardiovascular and Lymphatic Systems
    25. Structure and Function of the Cardiovascular and Lymphatic Systems
    26. Alterations of Cardiovascular Function
    27. Alterations of Cardiovascular Function in Children

    UNIT 8: The Pulmonary System
    28. Structure and Function of the Pulmonary System
    29. Alterations of Pulmonary Function
    30. Alterations of Pulmonary Function in Children

    UNIT 9: The Renal and Urologic Systems
    31. Structure and Function of the Renal and Urologic Systems
    32. Alterations of Renal and Urinary Tract Function
    33. Alterations of Renal and Urinary Tract Function in Children

    UNIT 10: The Reproductive Systems
    34. Structure and Function of the Reproductive Systems
    35. Alterations of the Female Reproductive System
    36. Alterations of the Male Reproductive System

    UNIT 11: The Digestive System
    37. Structure and Function of the Digestive System
    38. Alterations of Digestive Function
    39. Alterations of Digestive Function in Children

    UNIT 12: The Musculoskeletal and Integumentary Systems
    40. Structure and Function of the Musculoskeletal System
    41. Alterations of Musculoskeletal Function
    42. Alterations of Musculoskeletal Function in Children
    43. Structure, Function, and Disorders of the Integument
    44. Alterations of the Integument in Children
  • Sue E. Huether, MS, PhD, Professor Emeritus, College of Nursing, University of Utah, Salt Lake City, UT, USA, Kathryn L. McCance, MS, PhD, Professor, College of Nursing, University of Utah, Salt Lake City, UT, USA and Valentina L. Brashers, MD, FACP, FNAP, Professor of Nursing and Woodard Clinical Scholar, Attending Physician in Internal Medicine,, Director, Center for ASPIRE University of Virginia, USA
Not Yet Available
Most review copies are eBooks – how fast!
A review copy request is most likely to be fulfilled as an eBook on VitalSource rather than a print product, unless no eBook is available. eBooks become available in as little as a few hours. Print products will take between 7 and 10 days to arrive. To request a print copy, please contact us through the Evolve Support Center for further assistance or contact your Education Solutions Consultant.
Coming Soon!
Expected availability date: 02-03-2025
Important note
This is a Faculty Product!
Any student who attempts to request a review copy will be reported to the school's faculty and administration.
Technical Support
Contact your education consultant to learn more about adopting this product