cover image - Understanding Pathophysiology - Elsevier eBook on VitalSource, 8th Edition
ISBN: 9780323938068
Copyright: 2026
Publication Date: 01-21-2025
Page Count: 1136
Imprint: Elsevier
List Price: $126.99

Understanding Pathophysiology - Elsevier eBook on VitalSource, 8th Edition

by Sue E. Huether, MS, PhD, Kathryn L. McCance, MS, PhD and Valentina L. Brashers, MD, FACP, FNAP

Elsevier eBook on VitalSource

cover image - Understanding Pathophysiology - Elsevier eBook on VitalSource, 8th Edition
ISBN: 9780323938068
Copyright: 2026
Publication Date: 01-21-2025
Page Count: 1136
Imprint: Elsevier
List Price: $126.99
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Provide your students with in-depth knowledge of the concepts and processes of disease! Understanding Pathophysiology, 8th Edition provides a concise, comprehensive introduction to the way diseases work and how changes occur in the body as a result. With a clinically focused approach, the book begins by explaining cell structure and function. It then examines alterations by body systems and provides a practical guide to clinical manifestations, summaries of treatment, and health promotion strategies. This edition adds new algorithms, case studies for the Next-Generation NCLEX® Exam, and updated content on COVID-19, obesity, and cancer epidemiology. Ideal for nurses and other health professionals alike, this text helps students master important concepts and develop clinical judgment.
    • NEW! Case studies for the Next-Generation NCLEX® Exam (NGN) are provided on the Evolve website, helping students develop clinical judgment
    • NEW! Content updates address infectious disease, COVID-19 and post-COVID conditions, systemic pathophysiologic effects of obesity, cancer epidemiology, and more
    • NEW! Additional new algorithms show the pathophysiologic pathways and progression of disease
    • Consistent presentation of each disease includes pathophysiology, clinical manifestations, and evaluation and treatment
    • Lifespan content includes nine separate chapters with pediatric content and special sections on aging within the adult chapters, along with special boxes that highlight aging and pediatric content
    • More than 1000 images include photographs showing pathologic features of disease as well as micrographs showing normal and abnormal cellular structure
    • Risk Factor boxes show how certain risk factors are associated with specific diseases
    • Quick Check boxes appear at the end of major sections and are designed to help students recall the most important content
    • End-of-chapter Summary Reviews highlight the major concepts presented in each chapter
    • Did You Know boxes discuss new developments in biologic research, diagnostic studies, preventive care, treatments, and more
    • Key Terms are bolded, and listed with page numbers at the end of each chapter
    • Student resources on Evolve include animations, review questions, chapter summaries, and answers to the Quick Check questions
    • Instructor resources on Evolve include an image collection, TEACH lesson plans with case studies, PowerPoint® slides, NGN case studies, a conversion guide, and a test bank
  • 1. Cellular Biology
    2. Genes and Genetic Diseases
    3. Epigenetics and Disease
    4. Altered Cellular and Tissue Biology
    5. Fluids and Electrolytes, Acids and Bases
    6. Innate Immunity: Inflammation and Wound Healing
    7. Adaptive Immunity
    8. Alterations of Immunity
    9. Infection
    10. Stress and Disease
    11. Cancer Biology
    12. Cancer Epidemiology
    13. Cancer in Children and Adolescents
    14. Structure and Function of the Neurologic System
    15. Pain, Temperature, Sleep, and Sensory Function
    16. Alterations of Cognitive Systems, Cerebral Hemodynamics, and Motor Function
    17. Alterations of the Brain, Spinal Cord, and Peripheral Nerves
    18. Alterations of Neurologic Function in Children
    19. Mechanisms of Hormonal Regulation
    20. Alterations of Hormonal Regulation
    21. Obesity, Starvation, and Anorexia of Aging
    22. Structure and Function of the Hematologic System
    23. Alterations of Hematologic Function
    24. Alterations of Hematologic Function in Children
    25. Structure and Function of the Cardiovascular and Lymphatic Systems
    26. Alterations of Cardiovascular Function
    27. Alterations of Cardiovascular Function in Children
    28. Structure and Function of the Pulmonary System
    29. Alterations of Pulmonary Function
    30. Alterations of Pulmonary Function in Children
    31. Structure and Function of the Renal and Urologic Systems
    32. Alterations of Renal and Urinary Tract Function
    33. Alterations of Renal and Urinary Tract Function in Children
    34. Structure and Function of the Reproductive Systems
    35. Alterations of the Female Reproductive System
    36. Alterations of the Male Reproductive System
    37. Structure and Function of the Digestive System
    38. Alterations of Digestive Function
    39. Alterations of Digestive Function in Children
    40. Structure and Function of the Musculoskeletal System
    41. Alterations of Musculoskeletal Function
    42. Alterations of Musculoskeletal Function in Children
    43. Structure, Function, and Disorders of the Integument
    44. Alterations of the Integument in Children
  • Sue E. Huether, MS, PhD, Professor Emerita, College of Nursing, University of Utah, Salt Lake City, Utah, Kathryn L. McCance, MS, PhD, Professor Emerita, College of Nursing, University of Utah, Salt Lake City, Utah and Valentina L. Brashers, MD, FACP, FNAP, Professor Emerita, University of Virginia, Charlottesville, Virginia
    • Ways of Reading
      • The appearance of the text and page layout can be modified according to the capabilities of the reading system (font family and font size, spaces between paragraphs, sentences, words, and letters, as well as color of background and text)
      • This e-publication is accessible to the full extent that the file format and types of content allow, on a specific reading device, by default, without necessarily including any additions such as textual descriptions of images or enhanced navigation
      • All content can be read as read aloud speech or dynamic braille
      • Has alternative text descriptions for images
    • Conformance
    • Navigation
      • Table of contents to all chapters of the text via links
      • Index with links to referenced entries
      • Elements such as headings, tables, etc. for structured navigation
      • Page list to go to pages from the print source version
    • Rich Content
      • Math formulas in accessible format (MathML)
      • Information-rich images are described by extended descriptions
    • Hazards
      • The publication contains no hazards
    • Product Content
      • Content includes any type of illustrations.
      • The primary content is text.
      • Content includes maps and/or other cartographic content.
      • Content includes a significant number of actionable (clickable) web links to external content, downloadable resources, supplementary material, etc.
      • Content includes a significant number of actionable (clickable) cross-references, hyperlinked notes and annotations, or with other actionable links between largely textual elements (e.g., quiz/test questions, 'choose your own ending', etc.).
      • Content includes photographs, whether in a plate section / insert or not.
      • Content includes figures, diagrams, charts and/or graphs, including other 'mechanical' (i.e. non-photographic) illustrations.
      • Content includes images displayed in a specific order for the purpose of graphic storytelling or giving information (e.g. graphic novels, comics and manga). May include text integrated into the image (as speech and thought bubbles, textual 'sound' effects, captions etc.).
      • Content includes text within images, including text-as-text embedded in diagrams, charts, or within images containing speech balloons, thought bubbles, captions, etc.
      • Content includes visual content that is purely decorative and is not necessary to understanding of the content.
      • Content includes chemical notations, formulae.
      • Content includes mathematical notations, formulae.
      • At least some text - including text within other images - is 'text as an image' (i.e., a picture of text).
    • Legal Considerations
      • No information is available
    • Additional Accessibility Information
      • Content is enhanced with ARIA roles to optimize organization and facilitate navigation
      • Page breaks included from the original print source
      • For readers with color vision deficiency, use of color (e.g., in diagrams, graphics and charts, in prompts, or on buttons inviting a response) is not the sole means of graphical distinction or of conveying information
      • The body text is presented with a contrast ratio of at least 4.5:1 (or 3:1 for large/heading text)
      • Ultra-high contrast between text and background
      • E-publication includes basic navigation (usually less detailed than TOC-based navigation)
      • Where links, controls or buttons are included in the content, the purpose or functionality of each link, control or button is apparent from the associated text alone - or where it is unclear, separate link, control or button descriptions are provided
      • All (or substantially all) textual matter is arranged in a single logical reading order (including text that is visually presented as separate from the main text flow, e.g., in boxouts, captions, tables, footnotes, endnotes, citations, etc.). Non-textual content is also linked from within this logical reading order. (Purely decorative non-text content can be ignored).
      • Content provides explanations for unusual words, abbreviations, acronyms, idioms, jargon in an accessible form, such as glossaries, scripted pop-ups.
      • Where interactive content is included in the product, controls are provided (e.g., for speed, pause and resume, reset) and labelled to make their use clear.
      • The language of the text has been specified (e.g., via the HTML or XML lang attribute) to optimise text-to-speech (and other alternative renderings), both at the whole document level and, where appropriate, for individual words, phrases or passages in a different language.
Most review copies are eBooks – how fast!
A review copy request is most likely to be fulfilled as an eBook on VitalSource rather than a print product, unless no eBook is available. eBooks become available in as little as a few hours. Print products will take between 7 and 10 days to arrive. To request a print copy, please contact us through the Evolve Support Center for further assistance or contact your Elsevier Sales Rep.
An Access Code
Important note
You are viewing the faculty version.
Students requesting access will be reported.
Student access
Technical Support
Contact your Elsevier Sales Rep to learn more about adopting this product