Provides clear, comprehensive coverage of neonatal neurology in Dr. Joseph Volpe’s own legendary, readable manner—for a masterful, cohesive source of answers to any question that arises in your practice
Brings the latest science into the clinical setting, with an emphasis on translating new knowledge to the infant’s bedside
Offers comprehensive updates with summary tables and text to reflect major advances in the study of hemorrhage; new insights into molecular genetics and molecular characterization of brain tumors; significant advances in drugs and the developing nervous system; and much more
Includes new chapters on fetal neurology which address the importance of understanding and investigating the maternal-fetal origins of neonatal disease, as well as new chapters on neurodevelopmental follow-up, inflammation, and neurology in low-resource settings
Contains more than 1,000 illustrations: clinical and pathological specimens, key experimental findings, schematics, algorithms, anatomical drawings, and neuroimaging throughout, as well as numerous tables and boxes that synthesize key points
An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud
UNIT I: HUMAN BRAIN DEVELOPMENT 1. Neural Tube Development 2. Prosencephalic Development 3. Ventricular Development, Ventriculomegaly, and Hydrocephalus in the Fetus and Newborn 4. Normal and Abnormal Development of the Posterior Fossa Structures 5. Neuronal Proliferation 6. Neuronal Migration 7. Organizational Events 8. Myelination Events
UNIT II: FETAL NEUROLOGY 9. Specialized Diagnostic Studies for Assessment of the Fetal Central Nervous System 10. Placental Conditions With Consequences for the Fetal Brain 11. Maternal and Fetal Conditions With Consequences for the Fetal Brain
UNIT III: NEUROLOGICAL EVALUATION 12. Neurological Examination: Normal and Abnormal Features 13. Specialized Neurological Studies 14. Neurodevelopmental Follow-Up of High-Risk Newborns
UNIT IV: SEIZURES 15. Neonatal Seizures
UNIT V: HYPOXIC-ISCHEMIC AND RELATED DISORDERS 16. Pathophysiology: General Principle 17. Inflammation and the Newborn Brain 18. Encephalopathy of Prematurity: Neuropathology 19. Encephalopathy of Prematurity: Pathophysiology 20. Encephalopathy of the Preterm—Clinical Aspects 21. Intrauterine and Intrapartum Assessment of the Fetus 22. Hypoxic-Ischemic Encephalopathy in the Term Infant: Neuropathology 23. Hypoxic-Ischemic Injury in the Term Infant: Pathophysiology 24. Hypoxic-Ischemic Injury in the Term Infant: ClinicalNeurological Features, Diagnosis, Imaging, Management, and Prognosis 25. Stroke in the Newborn
Joseph J. Volpe, MD, Bronson Crothers Professor of Neurology, Emeritus, Harvard Medical School, Neurologist-in-Chief, Emeritus, Boston Children’s Hospital, Department of Pediatric Newborn Medicine, Harvard Institutes of Medicine, Boston, Massachusetts, USA and Terrie E. Inder, MB, ChB, MD, Mary Ellen Avery Professor of Pediatrics, Harvard Medical School, Chair, Department of Pediatric, Newborn Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA
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