Pharmacology - Elsevier eBook on VitalSource, 12th Edition

UNIT I Introduction to Pharmacology
1 The Clinical Judgment Measurement Model and the
Nursing Process
Clinical Judgment and the Nursing Process
Clinical Judgment Measurement Model
2 Drug Development and Ethical Considerations
Core Ethical Principles
Objectives and Phases of Pharmaceutical
Research
American Nurses Association Code of Ethics
Drug Standards and Legislation
Drug Names and Resources
3 Pharmacokinetics and Pharmacodynamics
Pharmacokinetics
Pharmacodynamics
Drug Interactions
4 Pharmacogenetics
Foundations of Pharmacogenetics
Key Considerations When Using
Pharmacogenetics
5 Complementary and Alternative Therapies
Dietary Supplement Health and Education Act of 1994
and Current Good Manufacturing Practices
Commonly Used Herbal Remedies
Hazards, Tips, and Resources for Herbal Remedies
6 Pediatric Considerations
Pharmacokinetics and Pharmacodynamics
Nursing Implications
Considerations for the Adolescent Patient
Family-Centered Collaborative Care
7 Drug Therapy in Older Adults
Physiologic Changes
Nursing Implications: Older Adult Drug Dosing and
Monitoring
8 Drugs in Substance Use Disorder
Substance Use Disorder
Types of Substance Use Disorders
Special Needs of Patients With Substance
Use Disorder
The Nurse With Substance Use Disorder

UNIT II Pharmacotherapy and Drug Administration
9 Safety and Quality
“Six Rights” of Medication Administration
Promoting Safety in the Health Care
Environment
Safety Risks With Medication Administration
Other Factors in the Prevention of Medication
Errors
10 Drug Administration
Forms and Routes of Drug Administration
Parenteral Medications
11 Drug Labels and Dosage Calculations
Overview of Dosage Calculations
Calculation Methods
Considerations for Enteral Administration
Considerations for Parenteral Administration
Answers to Practice Problems

UNIT III Maintenance of Homeostasis
12 Fluid Volume and Electrolytes
Fluid and Electrolyte
Fluid Replacement
Electrolytes
13 Vitamin and Mineral Replacement
Vitamins
Minerals
14 Nutritional Support
Nutritional Support Therapy
Enteral Nutrition
Parenteral Nutrition

UNIT IV Autonomic Nervous System Drugs
15 Adrenergic Agonists and Antagonists
Nervous Systems of the Body
Adrenergic Agonists
Adrenergic Antagonists
16 Cholinergic Agonists and Antagonists
Parasympathetic Nervous System
Cholinergic Agonists
Cholinergic Antagonists

UNIT V Central and Peripheral Nervous
System Drugs
17 Stimulants
Anatomy and Physiology of the Nervous System
Central Nervous System Stimulants
Amphetamines and Amphetamine-Like Drugs
Anorexiants
Analeptics
18 Depressants
Jared Robertson
Sleep Disorders
Sedative-Hypnotics
Anesthetics
19 Antiseizure Drugs
Seizures
Antiseizure Drugs
Antiseizure Drugs in Selected Situations
20 Drugs for Parkinson and Alzheimer Disease
Parkinson Disease
Drugs Used to Treat Parkinson Disease
Alzheimer Disease
21 Drugs for Neuromuscular Disorders and
Muscle Spasms
Myasthenia Gravis
Multiple Sclerosis
Skeletal Muscle Relaxants

UNIT VI Mental and Behavioral Health Drugs
22 Antipsychotics and Anxiolytics
Pschopathology
Antipsychotics
Anxiety
Anxiolytics
23 Antidepressants and Mood Stabilizers
Depression
Antidepressant Agents
Mood Stabilizers
UNIT VII Pain and Inflammation Management
Drugs
24 Antiinflammatories
Inflammation and Antiinflammatory Agents
Nonsteroidal Antiinflammatory Drugs and
Corticosteroids
Disease-Modifying Antirheumatic Drugs
Antigout Drugs
25 Analgesics
Pain
Nonopioid Analgesics
Opioid Analgesics
Adjuvants, Agonists, and Antagonists
Headaches: Migraine and Cluster

UNIT VIII Antimicrobial Drugs
26 Penicillins, Other Beta-Lactams, and Cephalosporins
Pathophysiology
Antibacterials/Antibiotics
Penicillins and Other Beta-Lactam Antibacterials
Cephalosporins
27 Macrolides, Oxazolidinones, Lincosamides,
Glycopeptides, and Lipopeptides
Macrolides
Oxazolidinones
Lincosamides
Glycopeptides
Lipopeptides
28 Tetracyclines, Glycylcyclines, Aminoglycosides, and
Fluoroquinolones
Tetracyclines
Glycylcyclines
Aminoglycosides
Fluoroquinolones
29 Sulfonamides and Nitroimidazoles Antibiotics
Sulfonamides
Trimethoprim-Sulfamethoxazole
Sulfonamides, Nitroimidazoles, Miscellaneous
Antibacterials
Miscellaneous Antibacterial Drugs
30 Antituberculars, Antifungals, and Antivirals
Tuberculosis
Antitubercular Drugs
Fungus: Pathophysiology
Viruses: Pathophysiology
31 Antimalarials, Anthelmintics, and Peptides
Antimalarial Drugs
Anthelmintic Drugs
Peptides

UNIT IX Immunologic Drugs
32 HIV- and AIDS-Related Drugs
Overview of HIV and AIDS
Antiretroviral Drugs
The Nurse’s Role in Antiretroviral Therapy
33 Transplant Drugs
Principles of Immunosuppression and
Immunosuppressant Drugs
Drugs for Transplant Rejection
Drugs for Infection
Promoting Adherence
34 Vaccines
Immunity
Vaccines
Vaccine-Preventable Diseases and Vaccine
Recommendations
Vaccine Safety: Reporting Diseases and Adverse
Reactions
Varicella Vaccine
Future Developments in Vaccines

UNIT X Antineoplastics and Biologic
Response Modifiers
35 Anticancer Drugs
Overview of Cancer
Cancer Chemotherapy
Alkylating Drugs
Antimetabolites
Antitumor Antibiotics
Plant Alkaloids
Other Drugs to Treat Cancer
36 Targeted Therapies to Treat Cancer
Overview of Targeted Therapy
Angiogenesis Inhibitors/Vascular Endothelial
Growth Factor Receptor Inhibitors
Epidermal Growth Factor Receptor Inhibitors
Tyrosine Kinase Inhibitors and
Multikinase Inhibitors
mTOR Kinase Inhibitors and Proteasome
Inhibitors
Monoclonal Antibodies
37 Biologic Response Modifiers
Overview of Biologic Response Modifiers
Interferons
Colony-Stimulating Factors
Interleukin-2

Linda E. McCuistion, PhD, MSN, RN, Professor (Ret.), University of Holy Cross, New Orleans, Louisiana, USA, Kathleen Vuljoin DiMaggio, MSN, RN, Professor Emerita, University of Holy Cross, New Orleans, Louisiana, USA, Mary B. Winton, PhD, MSN, RN, Associate Professor, Tarleton State University, Stephenville, Texas, USA and Jennifer J. Yeager, PhD, MSN, RN, Associate Professor, Tarleton State University, Stephenville, Texas, USA