Crash Course Haematology and Immunology, 6th Edition
by Priya Sriskandarajah, Ioanna Lazana, Maheen Ahsan and Michael Lim
Paperback
ISBN:
9780443249969
Copyright:
2026
Page Count:
223
Imprint:
Elsevier
List Price:
$40.99
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- Fully aligned to MLA requirements, with key ‘conditions’ and ‘presentations’ highlighted in handy checklists - save valuable revision time and be confident you have the syllabus covered
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1 Principles of haematology
Principles
Blood
Blood cells
Haematopoiesis
Bone marrow
The spleen
Lymphadenopathy
2 Red blood cells and haemoglobin
Erythrocytes
Erythropoiesis
Haemoglobin
Myoglobin
Iron and haem metabolism
Haemoglobin metabolism
Red cell cytoskeleton
Red cell metabolism
Methaemoglobinaemia
Full blood count and reticulocyte count
Peripheral blood film
3 Red blood cell disorders
Anaemia
Anaemia secondary to haematinic deficiency
Anaemia of chronic disease
Anaemia due to blood loss
Microcytic anaemia: other causes
Haemolytic anaemia
Antibody-mediated haemolysis
Intrinsic red cell defects causing haemolysis
Other causes of haemolysis
Haemoglobinopathies
Electrophoresis: investigation of haemoglobinopathies
Marrow defects causing anaemia
Polycythaemia
4 White blood cells
Leucocyte structure
Leucocyte differentiation
Left and right shift
White count differential
Leucocytosis
Leucopoeni
5 Haematological malignancies
Introduction
Myeloproliferative neoplasms
Myelodysplastic syndromes
Leukaemias
Acute leukaemias
Chronic leukaemias
Malignant lymphomas
Age-specific haematological malignancy risk
Plasma cell dyscrasias
Investigations in haematological malignancy
Chemotherapy and targeted treatments
6 Haemostasis
Introduction
Platelets
Antiplatelet drugs
Platelet disorders
The coagulation cascade
Traditional pathways
Currently accepted pathway
Regulation of coagulation
Fibrinolysis
Overview of haemostasis
Coagulation assays
Clotting factor disorders
Hereditary factor deficiencies
Thrombosis
Secondary (acquired) thrombophilias
Primary (hereditary) thrombophilias
Venous thromboembolism
Anticoagulation
Thromboprophylaxis
Therapeutic thrombolysis
7 Blood transfusion
Introduction
Red cell antigens
The ABO blood group system
Rh blood group system
Other red cell antigens
Red cell transfusions
Alternatives to red cell transfusions
Other transfusion products
Transfusion reactions
Major haemorrhage
8 Principles of immunology
An introduction to immunology
9 The innate immune system
Barriers to infection
Cells of innate immunity
Soluble proteins
Innate immune system pattern recognition molecules
10 The adaptive immune system
The immunoglobulin domain
Generation of antigen receptor diversity
Humoral immunity
Cell-mediated immunity
Tolerance
11 The functioning immune system
Response to tissue damage
Immune response to pathogens
12 Immune dysfunction
Hypersensitivity
Type I hypersensitivity (immediate hypersensitivity)
Type II hypersensitivity
Type III hypersensitivity (immune complex)
Type IV hypersensitivity (delayed-type hypersensitivity)
Immune system disorders (instead of ‘development of hypersensitivity’)
Examples of autoimmune diseases
Immune deficiency
Investigation of a patient with possible immune deficiency
13 Medical intervention
Immunization
Transplantation
Medications used for the prevention of immune rejection
Cancer immunotherapy
Self-Assessment
MLA High Yield Association Table
MLA Single Best Answer (SBA) Questions
MLA SBA Answers
Short Cases
Glossary
Index
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Priya Sriskandarajah, Ioanna Lazana, Maheen Ahsan and Michael Lim