Histology and Cell Biology: An Introduction to Pathology, 6th Edition

• Features new content on cancer immunotherapy, satellite cells and muscle repair, vasculogenesis and angiogenesis in relation to cancer treatment, and mitochondria replacement therapies. • Presents new material on ciliogenesis, microtubule assembly and disassembly, chromatin structure and condensation, and X chromosome inactivation, which directly impact therapy for ciliopathies, infertility, cancer, and Alzheimer’s disease. • Provides thoroughly updated information on gestational trophoblastic diseases, molecular aspects of breast cancer, and basic immunology, including new illustrations on the structure of the T-cell receptor, CD4+ cells subtypes and functions, and the structure of the human spleen. • Uses a new, light green background throughout the text to identify essential concepts of histology – a feature requested by both students and instructors to quickly locate which concepts are most important for beginning learners or when time is limited. These essential concepts are followed by more detailed information on cell biology and pathology. • Contains new Primers in most chapters that provide a practical, self-contained integration of histology, cell biology, and pathology – perfect for clarifying the relationship between basic and clinical sciences. • Identifies clinical terms throughout the text and lists all clinical boxes in the table of contents for quick reference. • Helps students understand the links between chapter concepts with concept mapping animations on Student Consult™ –　an outstanding supplement to in-class instruction.

• Thorough update throughout

PART I BASIC TISSUES AND INTEGRATED CELL BIOLOGY AND GENERAL PATHOLOGY Chapter 1 EPITHELIUM Chapter 2 EPITHELIAL GLANDS Chapter 3 CELL SIGNALING Chapter 4 CONNECTIVE TISSUE Chapter 5 OSTEOGENESIS Chapter 6 BLOOD AND HEMATOPOIESIS Chapter 7 MUSCLE TISSUE Chapter 8 NERVOUS TISSUE Chapter 9 SENSORY ORGANS: VISION AND HEARING PART II ORGAN SYSTEMS: PROTECTION OF THE BODY Chapter 10 IMMUNE-LYMPHATIC SYSTEM Chapter 11 INTEGUMENTARY SYSTEM PART III ORGAN SYSTEMS: BLOOD CIRCULATORY SYSTEMS Chapter 12 CARDIOVASCULAR SYSTEM Chapter 13 RESPIRATORY SYSTEM Chapter 14 URINARY SYSTEM PART IV ORGAN SYSTEMS: THE ALIMENTARY SYSTEM Chapter 15 UPPER DIGESTIVE SEGMENT Chapter 16 LOWER DIGESTIVE SEGMENT Chapter 17 DIGESTIVE GLANDS PART V ORGAN SYSTEMS: THE ENDOCRINE SYSTEM Chapter 18 NEUROENDOCRINE SYSTEM Chapter 19 ENDOCRINE SYSTEM PART VI ORGAN SYSTEMS: THE REPRODUCTIVE SYSTEM Chapter 20 SPERMATOGENESIS Chapter 21 SPERM TRANSPORT AND MATURATION Chapter 22 FOLLICLE DEVELOPMENT AND THE MENSTRUAL CYCLE Chapter 23 FERTILIZATION, PLACENTATION, AND LACTATION

Abraham L Kierszenbaum, M.D., Ph.D., Emeritus Medical (Clinical) Professor, The Sophie Davis School of Biomedical Education, The City University of New York, New York, New York and Laura Tres, M.D., Ph.D., Emeritus Medical (Clinical) Professor, The Sophie Davis School of Biomedical Education, The City University of New York, New York, New York