Bridging the gap between basic science and clinical practice, Nunn and Lumb's Applied Respiratory Physiology, 10th Edition, provides a concise, single-volume guide to all aspects of respiratory physiology in health and disease, translating core respiratory physiology into practical applications and clinically relevant material. For more than 50 years, this text has been invaluable to those in training or preparing for examinations in anaesthesia, intensive care, respiratory medicine, or thoracic surgery, as well as an essential quick reference for physiologists other practitioners. In this revised edition, all content has been thoroughly reviewed and updated, incorporating numerous new topics, updated summaries for each chapter, and a robust collection of student-friendly online features.
Provides a unique, one-stop guide to all aspects of respiratory physiology in health, disease, and in the many physiologically challenging situations and environments into which humans take themselves
Explains complex concepts clearly and offers easy-to-understand explanations of basic science, assisted by the extensive use of diagrams
Features a new chapter covering all aspects of lung immunology, including non-immune pulmonary defences against inhaled pathogens, and both innate and adaptive immunity
Contains new topics throughout: including genetic treatments for sickle cell disease, physiological effects of e-cigarettes, recent breakthroughs in the drug treatment of cystic fibrosis, pathophysiology of SARS-CoV-2 infection, principles and delivery of high flow nasal therapy, clinical effects of hyperoxia in acute medical conditions, updates on peri-operative respiratory management, and more
Includes content that is difficult to find in general physiology texts, such as respiratory function in pregnancy, neonates, and children; the impact of the obesity epidemic on respiratory physiology; the evolving understanding of the harms caused by hyperoxia; basic science and the clinical problems of respiratory critical care; peri-operative lung management and pulmonary complications; and ventilation and pulmonary care advances accelerated by the SARS-CoV-2 pandemic
Covers additional related topics such as solutions to the challenges of respiratory gas exchange across the animal kingdom, space and diving physiology, and more
Provides robust online features, including two bonus chapters; presentations by Dr. Lumb on key topics from the book, and more than 100 self-assessment questions linked to each chapter with answers and explanations
An eBook version is included with purchase. The eBook allows access to all of the text, figures, and references, with the ability to search, make notes and highlights, and have content read aloud
1. Functional anatomy of the respiratory tract 2. Elastic forces and lung volumes 3. Respiratory system resistance 4. Control of breathing 5. Pulmonary ventilation 6. The pulmonary circulation 7. Distribution of pulmonary ventilation and perfusion 8. Diffusion of respiratory gases 9. Carbon dioxide 10. Oxygen 11. Nonrespiratory functions of the lung 12. Pregnancy, neonates and children 13. Exercise 14. Sleep 15. High altitude and flying 16. High pressure and diving 17. Respiration in closed environments and space 18. Drowning 19. Smoking and air pollution 20. Anaesthesia 21. Changes in the carbon dioxide partial pressure 22. Hypoxia 23. Anaemia 24. Oxygen toxicity and hyperoxia 25. Comparative respiratory 26. Ventilatory failure 27. Airways disease 28. Pulmonary vascular disease 29. Diseases of the lung parenchyma and pleura 30. Acute lung injury 31. Respiratory support and artificial ventilation 32. Pulmonary surgery 33. The atmosphere 34. The history of respiratory physiology
Andrew B. Lumb, MB, BS, FRCA, Consultant Anaesthetist, St James' University Hospital; Honorary Clinical Associate Professor in Anaesthesia, University of Leeds, Leeds, UK and Caroline R. Thomas, BSC, MBChB, MRCS(Ed), FRCA, Consultant Anaesthetist, St James's Hospital, Leeds and Honorary Senior Clinical Lecturer, University of Leeds, Leeds, UK
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