Clinical Biochemistry, 6th Edition
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This comprehensively revised edition of Clinical Biochemistry offers essential reading for today’s students of medicine and other health science disciplines – indeed, anyone who requires a concise, practical introduction to the subject. Topics are clearly presented in a series of double-page ‘learning units’, each covering a particular aspect of clinical biochemistry. Four sections provide a core grounding in the subject:
- Introducing clinical biochemistry gives an insight into how modern hospital laboratories work, and includes an entirely new series of learning units on the interpretation of test results
- Core biochemistry covers the bulk of routine analyses, and their relevance to the clinical setting
- Endocrinology provides an overview of endocrine investigations as well as a practical approach to thyroid, adrenal, pituitary and gonadal function testing
- Specialised investigations embraces an assortment of other topics that students may encounter
This edition represents the most radical revision of the book to date. Every learning unit has been examined and updated to reflect current developments and clinical best practice. Entirely new material includes a series of learning units on interpretation and analytical aspects of clinical biochemistry. Coverage of fluid biochemistry is now more comprehensive. New "Want to know more?" links throughout the book point readers to relevant further information.
- (Printed version) now includes the complete eBook version for the first time – downloadable for anytime access and enhanced with new, interactive multiple choice questions for each section, to test your understanding and aid exam preparation
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Part 1: Introducing clinical biochemistry
1 The clinical biochemistry laboratory
2 The use of the laboratory
3 Interpretation of results: general
4 Interpretation of results: diagnosis
5 Interpretation of results: monitoring
6 Analytical aspects
Part 2: Core biochemistry
7 Fluid and electrolytes: basic concepts
8 Water and sodium balance: physiological mechanisms
9 Hyponatraemia: pathophysiology
10 Hyponatraemia: assessment and management
11 Hypernatraemia
12 Hyperkalaemia
13 Hypokalaemia
14 Intravenous fluid therapy
15 Investigation of renal function (1)
16 Investigation of renal function (2)
17 Urinalysis
18 Proteinuria
19 Acute kidney injury
20 Chronic kidney disease
21 Acid–base: concepts and vocabulary
22 Metabolic acid–base disorders
23 Respiratory and mixed acid–base disorders
24 Acid–base disorders: diagnosis and management
25 Proteins and enzymes
26 Immunoglobulins
27 Myocardial infarction
28 Liver function tests
29 Jaundice
30 Liver disease
31 Glucose metabolism and diabetes mellitus
32 Diagnosis and monitoring of diabetes mellitus
33 Diabetic ketoacidosis
34 Hypoglycaemia
35 Calcium regulation and hypocalcaemia
36 Hypercalcaemia
37 Phosphate and magnesium
38 Metabolic bone disease
39 Osteoporosis and fragility fractures
Part 3: Endocrinology
40 Endocrine control
41 Dynamic function tests
42 Pituitary function
43 Growth disorders and acromegaly
44 Thyroid pathophysiology
45 Hypothyroidism
46 Hyperthyroidism
47 Adrenocortical pathophysiology
48 Hypofunction of the adrenal cortex
49 Hyperfunction of the adrenal cortex
50 Gonadal function
51 Subfertility
Part 4: Specialized investigations
52 Nutritional assessment
53 Nutritional support
54 Parenteral nutrition
55 The metabolic response to injury
56 Gastrointestinal disorders
57 Iron
58 Zinc and copper
59 Therapeutic drug monitoring
60 Toxicology
61 Metal poisoning
62 Alcohol
63 Ascites
64 Pleural fluid
65 Cerebrospinal fluid
66 Identification of body fluids
67 Lipoprotein metabolism
68 Clinical disorders of lipid metabolism
69 Hypertension
70 Cancer and its consequences
71 Tumour markers
72 Multiple endocrine neoplasia
73 Hyperuricaemia
74 Myopathy
75 Fetal monitoring and prenatal diagnosis
76 Pregnancy
77 Antenatal screening
78 Screening the newborn for disease
79 Paediatric biochemistry
80 Inborn errors of metabolism
81 Selected inherited disorders
Case history comments
Online self-assessment
Index
