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cover image - Medical Pharmacology and Therapeutics,6th Edition
ISBN: 9780702081590
Publication Date: 01-28-2022
Page Count: 752
Imprint: Elsevier
List Price: $70.99

Medical Pharmacology and Therapeutics, 6th Edition

by Derek G. Waller, BSc, DM, MBBS, FRCP, Anthony Sampson, MA, PhD, FHEA, FBPhS and Andrew Hitchings, BSc, MBBS, PhD, FRCP, FFICM, FHEA, FBPhS

Paperback

ISBN: 9780702081590
Publication Date: 01-28-2022
Page Count: 752
Imprint: Elsevier
List Price: $70.99
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    • A clinical focus throughout – suitable for medical, nursing and other healthcare students throughout their training
    • Thorough update of clinically-relevant medicines to ensure best practice
    • Information aligned with the British National Formulary (BNF), NICE guidelines and relevant professional benchmarks
    • Comprehensive drug compendia allow all drugs to be identified and placed within their respective classes
    • Extensive self-assessment questions to support learning and revision

    New to this edition

    • Expanded discussion of the pathophysiology and management of shock
    • Revised discussion of the management of chronic pain
    • Consideration of treatment of Covid-19
  • Preface, vii
    Drug Dosage and Nomenclature, viii
    SECTION 1 GENERAL PRINCIPLES, 1
    1. Principles of Pharmacology and Mechanisms of
    Drug Action, 1
    2. Pharmacokinetics, 32
    3. Drug Discovery, Safety and Efficacy, 62
    4. Neurotransmission and the Peripheral Autonomic
    Nervous System, 71
    SECTION 2 THE CARDIOVASCULAR SYSTEM, 89
    5. Ischaemic Heart Disease, 89
    6. Systemic and Pulmonary Hypertension, 108
    7. Heart Failure and Shock, 128
    8. Cardiac Arrhythmias, 142
    9. Cerebrovascular Disease and Dementia, 160
    10. Peripheral Artery Disease, 169
    11. Haemostasis, 175
    SECTION 3 THE RESPIRATORY SYSTEM, 192
    12. Asthma and Chronic Obstructive
    Pulmonary Disease, 192
    13. Respiratory Disorders: Cough, Respiratory
    Stimulants, Cystic Fibrosis, Idiopathic Pulmonary
    Fibrosis and Neonatal Respiratory Distress
    Syndrome, 211
    SECTION 4 THE RENAL SYSTEM, 218
    14. Diuretics, 218
    15. Disorders of Micturition, 229
    16. Erectile Dysfunction, 236
    SECTION 5 THE NERVOUS SYSTEM, 242
    17. General Anaesthetics, 242
    18. Local Anaesthetics, 252
    19. Opioid Analgesics and the Management of Pain, 258
    20. Anxiety, Obsessive-Compulsive Disorder and
    Insomnia, 273
    21. Schizophrenia and Bipolar Disorder, 281
    22. Depression, Attention Deficit Hyperactivity
    Disorder and Narcolepsy, 292
    23. Seizures and Epilepsy, 308
    24. Extrapyramidal Movement Disorders and
    Spasticity, 323
    25. Other Neurological Disorders: Multiple Sclerosis,
    Motor Neuron Disease and Guillain–Barré
    Syndrome, 336
    26. Migraine and Other Headaches, 342
    SECTION 6 THE MUSCULOSKELETAL SYSTEM, 350
    27. The Neuromuscular Junction and Neuromuscular
    Blockade, 350
    28. Myasthenia Gravis, 357
    29. Nonsteroidal Antiinflammatory Drugs, 361
    vi Contents
    30. Rheumatoid Arthritis, Other Inflammatory
    Arthritides and Osteoarthritis, 371
    31. Hyperuricaemia, Gout and Pseudogout, 383
    SECTION 7 THE GASTROINTESTINAL SYSTEM, 389
    32. Nausea and Vomiting, 389
    33. Dyspepsia, Peptic Ulcer Disease and
    Gastrooesophageal Reflux Disease, 397
    34. Inflammatory Bowel Disease, 408
    35. Constipation, Diarrhoea and Irritable Bowel
    Syndrome, 415
    36. Liver Disease, 423
    37. Obesity, 432
    SECTION 8 THE IMMUNE SYSTEM, 437
    38. The Immune Response and Immunosuppressant
    Drugs, 437
    39. Antihistamines and Allergic Disease, 450
    SECTION 9 The Endocrine System
    and Metabolism, 457
    40. Diabetes Mellitus, 457
    41. The Thyroid and Control of Metabolic Rate, 473
    42. Calcium Metabolism and Metabolic Bone
    Disease, 480
    43. Pituitary and Hypothalamic Hormones, 491
    44. Corticosteroids (Glucocorticoids and
    Mineralocorticoids), 503
    45. Female Reproduction, 512
    46. Androgens, Antiandrogens and Anabolic
    Steroids, 530
    47. Anaemia and Haematopoietic Colony-Stimulating
    Factors, 535
    48. Lipid Disorders, 545
    SECTION 10 The Skin and Eyes , 558
    49. Skin Disorders, 558
    50. The Eye, 567
    SECTION 11 A NTIMICROBIAL THERAPY, 578
    51. Drugs for Infections, 578
    SECTION 12 CANCER, 630
    52. Drugs for Cancer, 630
    SECTION 13 General Features: Toxicity
    and Prescribing , 661
    53. Drug Toxicity and Overdose, 661
    54. Substance Abuse and Dependence, 677
    55. Prescribing, Adherence and Information About
    Medicines, 693
    56. Drug Therapy in Special Situations, 700
    Index, 712
  • Derek G. Waller, BSc, DM, MBBS, FRCP, Former Consultant Physician and Senior Clinical Lecturer, Department of Medicine, University Hospital Southampton, Southampton United Kingdom, Anthony Sampson, MA, PhD, FHEA, FBPhS, Professorial Fellow in Clinical Pharmacology & Director of Undergraduate Programmes, Faculty of Medicine, University of Southampton Southampton, United Kingdom and Andrew Hitchings, BSc, MBBS, PhD, FRCP, FFICM, FHEA, FBPhS, Reader in Clinical Pharmacology, St George’s, University of London, Honorary Consultant in Neurointensive Care, St George’s University Hospitals NHS Foundation Trust, London
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