The Netter Collection of Medical Illustrations: Musculoskeletal System, Volume 6, Part III - Biology and Systemic Diseases, 2nd Edition

• Gain a rich clinical view of embryology; physiology; metabolic disorders; congenital and development disorders; rheumatic diseases; tumors of musculoskeletal system; injury to musculoskeletal system; soft tissue infections; and fracture complications in one comprehensive volume, conveyed through beautiful illustrations as well as up-to-date radiologic and laparoscopic images.
• Benefit from the expertise of Drs. Joseph Iannotti, Richard Parker, and esteemed colleagues from the Cleveland Clinic, who clarify and expand on the illustrated concepts.
• Clearly see the connection between basic science and clinical practice with an integrated overview of normal structure and function as it relates to pathologic conditions.
• See current clinical concepts in orthopaedics and rheumatology captured in classic Netter illustrations, as well as new illustrations created specifically for this volume by artist-physician Carlos Machado, MD, and others working in the Netter style.

1-1 Amphioxus and Human Embryo at 16

Days, 2

1-2 Differentiation of Somites into Myotomes,

Sclerotomes, and Dermatomes, 3

1-3 Progressive Stages in Formation of

Vertebral Column, Dermatomes, and

Myotomes; Mesenchymal Precartilage

Primordia of Axial and Appendicular

Skeletons at 5 Weeks, 4

1-4 Fate of Body, Costal Process, and Neural

Arch Components of Vertebral Column,

With Sites and Time of Appearance of

Ossification Centers, 5

1-5 First and Second Cervical Vertebrae at

Birth; Development of Sternum, 6

1-6 Early Development of Skull, 7

1-7 Skeleton of Full-Term Newborn, 8

1-8 Changes in Position of Limbs Before Birth;

Precartilage Mesenchymal Cell

Concentrations of Appendicular Skeleton

at 6 Weeks, 9

1-9 Changes in Ventral Dermatome Pattern

During Limb Development, 10

1-10 Initial Bone Formation in Mesenchyme;

Early Stages of Flat Bone Formation, 11

1-11 Secondary Osteon (Haversian

System), 12

1-12 Growth and Ossification of

Long Bones, 13

1-13 Growth in Width of a Bone and Osteon

Remodeling, 14

1-14 Remodeling: Maintenance of Basic

Form and Proportions of Bone During

Growth, 15

1-15 Development of Three Types of Synovial

Joints, 16

1-16 Segmental Distribution of Myotomes in

Fetus of 6 Weeks; Developing Skeletal

Muscles at 8 Weeks, 17

1-17 Development of Skeletal Muscle

Fibers, 18

1-18 Cross Sections of Body at 6 to

7 Weeks, 19

1-19 Prenatal Development of Perineal

Musculature, 20

1-20 Origins and Innervations of Pharyngeal

Arch and Somite Myotome Muscles, 21

1-21 Branchiomeric and Adjacent Myotomic

Muscles at Birth, 22

2-1 Microscopic Appearance of Skeletal

Muscle Fibers, 25

2-2 Organization of Skeletal Muscle, 26

2-3 Intrinsic Blood and Nerve Supply of

Skeletal Muscle, 27

2-4 Composition and Structure of

Myofilaments, 28

2-5 Muscle Contraction and Relaxation, 29

2-6 Biochemical Mechanics of Muscle

Contraction, 30

2-7 Sarcoplasmic Reticulum and Initiation of

Muscle Contraction, 31

2-8 Initiation of Muscle Contraction by Electric

Impulse and Calcium Movement, 32

2-9 Motor Unit, 33

2-10 Structure of Neuromuscular Junction, 34

2-11 Physiology of Neuromuscular

Junction, 35

2-12 Pharmacology of Neuromuscular

Transmission, 36

2-13 Physiology of Muscle Contraction, 37

2-14 Energy Metabolism of Muscle, 38

2-15 Muscle Fiber Types, 39

2-16 Structure, Physiology, and

Pathophysiology of Growth Plate, 40-41

2-17 Structure and Blood Supply of Growth

Plate, 42

2-18 Peripheral Fibrocartilaginous Element of

Growth Plate, 43

2-19 Composition and Structure of

Cartilage, 44

2-20 Bone Cells and Bone Deposition, 45

2-21 Composition of Bone, 46

2-22 Structure of Cortical (Compact) Bone, 47

2-23 Structure of Trabecular Bone, 48

2-24 Formation and Composition of

Collagen, 49

2-25 Formation and Composition of

Proteoglycan, 50

2-26 Structure and Function of Synovial

Membrane, 51

2-27 Histology of Connective Tissue, 52

2-28 Dynamics of Bone Homeostasis, 53

2-29 Regulation of Calcium and Phosphate

Metabolism, 54

2-30 Effects of Bone Formation and Bone

Resorption on Skeletal Mass, 55

2-31 Four Mechanisms of Bone Mass

Regulation, 56

2-32 Normal Calcium and Phosphate

Metabolism, 57

2-33 Nutritional Calcium Deficiency, 59

2-34 Effects of Disuse and Stress (Weight

Bearing) on Bone Mass, 60

2-35 Musculoskeletal Effects of Weightlessness

(Space Flight), 61

2-36 Bone Architecture and Remodeling in

Relation to Stress, 62

2-37 Stress-Generated Electric Potentials in

Bone, 63

2-38 Bioelectric Potentials in Bone, 64

2-39 Age-Related Changes in Bone

Geometry, 65

2-40 Age-Related Changes in Bone Geometry

(Continued), 66

3-1 Parathyroid Hormone, 68

3-2 Pathophysiology of Primary

Hyperparathyroidism, 69

3-3 Clinical Manifestations of Primary

Hyperparathyroidism, 70

3-4 Differential Diagnosis of Hypercalcemic

States, 71

3-5 Pathologic Physiology of

Hypoparathyroidism, 72

3-6 Clinical Manifestations of Chronic

Hypoparathyroidism, 74

3-7 Clinical Manifestations of

Hypocalcemia, 75

3-8 Pseudohypoparathyroidism, 76

3-9 Mechanism of Parathyroid Hormone

Activity on End Organ, 77

3-10 Mechanism of Parathyroid Hormone

Activity on End Organ: Cyclic AMP

Response to PTH, 78

3-11 Clinical Guide to Parathyroid Hormone

Assay: Different Forms of PTH and Their

Detection by Whole (Bioactive) PTH and

I-PTH Immunometric Assays, 79

3-12 Clinical Guide to Parathyroid Hormone

Assay (Continued), 80

3-13 Childhood Rickets, 81

3-14 Adult Osteomalacia, 82

3-15 Nutritional Deficiency: Rickets and

Osteomalacia, 83

3-16 Vitamin D–Resistant Rickets and

Osteomalacia due to Proximal Renal

Tubular Defects (Hypophosphatemic

Rachitic Syndromes), 84

3-17 Vitamin D–Resistant Rickets and

Osteomalacia due to Proximal and Distal

Renal Tubular Defects, 85

3-18 Vitamin D–Dependent (Pseudodeficiency)

Rickets and Osteomalacia, 86

3-19 Vitamin D–Resistant Rickets and

Osteomalacia due to Renal Tubular

Acidosis, 87

3-20 Metabolic Aberrations of Renal

Osteodystrophy, 88

3-21 Rickets, Osteomalacia, and Renal

Osteodystrophy, 89

3-22 Bony Manifestations of Renal

Osteodystrophy, 90

3-23 Vascular and Soft Tissue Calcification in