SECTION 1 Mechanisms of Drug Action and Therapeutic Principles 1. Introduction 2. Cellular Receptors and Drug Concentration-Response Relationships 3. Pharmacokinetics 4. Pharmacogenetics 5. Drug Discovery, Development, and Regulation
SECTION 2 Chemical Mediators and Drugs Affecting Autonomic and Neuromuscular Synapses 6. Introduction to the Autonomic Nervous System Cholinergic Drugs 7. Muscarinic Agonists, Cholinesterase Inhibitors, and Their Clinical Uses 8. Muscarinic Antagonists and Their Clinical Uses 9. Nicotinic Agonists and Their Clinical Uses 10. Neuromuscular Blocking Drugs and Nicotinic Antagonists Adrenergic Drugs 11. Adrenergic Agonists and Their Clinical Uses 12. Adrenergic Antagonists and Their Clinical Uses
SECTION 3 Drug Treatment for Disorders Affecting the Central Nervous System 13. The Central Nervous System 14. Drug Therapy for Alzheimer Disease and Other Cognitive Disorders/Dementias 15. Pharmacotherapy of Basal Ganglia Disorders: Parkinson Disease and Huntington Disease 16. Drug Therapy for Psychoses and Bipolar Disorder 17. Drug Therapy for Depression and Anxiety 18. Drug Therapy for the Management of Attention Deficit-Hyperactivity Disorder 19. Drug Therapy for Insomnia and the Hypersomnias 20. Drug Therapy for Managing Obesity and Eating Disorders 21. Treatment of Seizure Disorders 22. Drug Therapy for Spasticity Disorders 23. Ethanol, Other Alcohols, and Medications for Alcohol Use Disorder 24. Psychoactive Compounds and Substance Use Disorder
SECTION 4 Drug Therapy for Pain Management 25. Introduction 26. General Anesthetics 27. Local Anesthetics 28. Opioid Analgesics 29. Nonsteroidal Antiinflammatory Drugs and Acetaminophen 30. Cannabinoids 31. Drug Therapy for Migraine Headache
SECTION 5 Treatment of Inflammatory, Allergic and Immunologic Disorders 32. Drug Therapy for Gout and Hyperuricemia 33. Pharmacological Interventions for Allergic Reactions 34. Immunosuppressants for Autoimmune Disorders and Organ Transplantation 35. Drug Therapy for Rheumatoid Arthritis
SECTION 6 Drug Treatment for Cardiovascular Diseases 36. Introduction to the Regulation of Cardiovascular Function 37. Overview of Hypertension Management and Drugs That Decrease Sympathetic Tone 38. Diuretics and Drugs That Affect Volume and Electrolyte Content 39. Drugs Affecting the Renin-Angiotensin-Aldosterone System 40. Calcium-Channel Blockers 41. Vasodilators for Hypertensive Crises, Pulmonary Hypertension, and Erectile Dysfunction 42. Treatment of Hyperlipidemias and Atherosclerotic Cardiovascular Disease 43. Treatment of Myocardial Ischemia and Angina Pectoris 44. Treatment of Heart Failure 45. Antiarrhythmic Drugs 46. Anticoagulant, Antiplatelet, and Fibrinolytic Medications 47. Drug Therapy for Hemophilia and the Deficiency Anemias
SECTION 7 Treatment of Endocrine Disorders 48. Introduction to Endocrine Pharmacology 49. Treatment of Hypothalamic and Pituitary Disorders 50. Diagnosis and Treatment of Adrenocorticosteroid Disorders 51. Female Hormone Regulation 52. Androgens, Antiandrogens, and Their Clinical Uses 53. Drug Therapy for the Management of Diabetes 54. Drug Therapy for the Management of Thyroid Disorders 55. Calcium Regulating Hormones and Other Agents Affecting Bone
SECTION 8 Chemotherapy Infectious Diseases 56. Principles of Antimicrobial Use 57. Drugs Targeting Bacterial Cell Walls and Membranes 58. Drugs Targeting Bacterial Protein Synthesis 59. Drugs Targeting Bacterial DNA 60. Antimycobacterial Agents 61. Drugs Targeting Resistant Organisms Parasitic Diseases 62. Antifungal Agents 63. Antimalarial and Other Antiprotozoal Agents 64. Anthelmintics and Ectoparasiticides Viruses 65. Antiviral Agents 66. Antiretroviral Drugs for HIV Cancer 67. Principles of Cancer and Antineoplastic Drug Use 68. Cytotoxic Agents 69. Targeted Anticancer Agents 70. Immunological and Cell-Based Therapies
SECTION 9 Special Considerations 71. Therapeutic Use of Hematopoietic Growth Factors 72. Gastrointestinal Disorders and Their Treatment 73. Pharmacological Interventions for Asthma and Chronic Obstructive Pulmonary Disorders 74. Dietary Supplements, Nutraceuticals, and Natural Products 75. Essentials of Toxicology 76. Therapeutic Considerations for Pregnant, Pediatric, Geriatric, and Obese Individuals Hypersomnias
Lynn Wecker, PhD, Distinguished University Professor, Departments of Psychiatry and Behavioral Medicine and Molecular Pharmacology and Physiology, Director, Laboratory of Neuropsychopharmacology, USF College of Medicine, Tampa, Florida, USA and Susan L. Ingram, PhD, Professor of Neurological Surgery, School of Medicine, Oregon Health & Science University, Portland, Oregon, USA
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