Provide your students with the in-depth understanding of pathophysiology they need for patient care! Using a systems approach, Pathophysiology, 8th Edition, examines the etiology, pathogenesis, clinical manifestations, and treatment of diseases and disorders. The book begins with a review of normal anatomy and physiology, followed by pathophysiology and application of concepts to specific disorders. Each chapter includes a discussion of the disease processes and abnormalities that may occur, with a focus on the pathophysiologic concepts involved. Using a clear, concise writing style and a focus on critical thinking, this text emphasizes the major pathophysiology concepts relevant to clinical practice while not overwhelming the reader with minute detail.
NEW!Updated content throughout the book reflects the latest research and thinking in pathophysiology.
Clear, easy-to-read writing style is simplified by input from readability experts, and includesmany tables, boxes, and figures to highlight key content.
Thorough updates include information on the newest scientific findings and advances in treatment, more than 100 new figures for improved clarity, and more.
More than 1,000 full-color photos and illustrations help to clarify complex pathophysiological concepts and make the book visually appealing.
Global Health Care boxes summarize topics such asCOVID-19, HIV/AIDS, Ebola, tropical diseases, and more, with information on prevalence, mechanism of disease and transmission.
Pediatric and Older Adult Considerations boxes include brief analyses of age-related changes associated with specific body systems.
Student-friendly learning resources include chapter outlines, bolded key terms, key questions, Key Points boxes, Clinical Judgment challenges, and chapter summaries.
UNIT I: Pathophysiologic Processes 1. Introduction to Pathophysiology 2. Homeostasis, Allostasis, and Adaptive Responses to Stressors UNIT II: Cellular Function 3. Cell Structure and Function 4. Cell Injury, Aging, and Death 5. Genome Structure, Regulation, and Tissue Differentiation 6. Genetic and Developmental Disorders 7. Neoplasia UNIT III: Defense 8. Infectious Processes 9. Inflammation and Immunity 10. Alterations in Immune Function 11. Malignant Disorders of White Blood Cells 12. HIV Disease and AIDS UNIT IV: Oxygen Transport, Blood Coagulation, Blood Flow, and Blood Pressure 13. Alterations in Oxygen Transport 14. Alterations in Homeostasis and Blood Coagulation 15. Alterations in Blood Flow 16. Alterations in Blood Pressure UNIT V: Cardiac Function 17. Cardiac Function 18. Alterations in Cardiac Function 19. Heart Failure and Dysrhythmias: Common Sequelae of Cardiac Diseases 20. Shock UNIT VI: Respiratory Function 21. Respiratory Function and Alterations in Gas Exchange 22. Obstructive Pulmonary Disorders 23. Restrictive Pulmonary Disorders UNIT VII: Fluid, Electrolyte, and Acid-Base Homeostasis 24. Fluid and Electrolyte Homeostasis and Imbalances 25. Acid-Base Homeostasis and Imbalances UNIT VIII: Renal and Bladder Function 26. Renal Function 27. Intrarenal Disorders 28. Acute Kidney Injury and Chronic Kidney Disease 29. Disorders of the Lower Urinary Tract UNIT IX: Genital and Reproductive Function 30. Male Genital and Reproductive Function 31. Alterations in Male Genital and Reproductive Function 32. Female Genital and Reproductive Function 33. Alterations in Female Genital and Reproductive Function 34. Sexually Transmitted Infections UNIT X: Gastrointestinal Function 35. Gastrointestinal Function 36. Gastrointestinal Disorders 37. Alterations in Function of the Gallbladder and Exocrine Pancreas 38. Liver Diseases UNIT XI: Endocrine Function, Metabolism, and Nutrition 39. Endocrine Physiology and Mechanisms of Hypothalamic-Pituitary Regulation 40. Disorders of Endocrine Function 41. Diabetes Mellitus 42. Alterations in Metabolism and Nutrition UNIT XII: Neural Function 43. Structure and Function of the Nervous System 44. Acute Disorders of Brain Function 45. Chronic Disorders of Neurologic Function 46. Alterations in Special Sensory Function 47. Pain UNIT XIII Neuropsychological Function 48. Mental Health Disorders UNIT XIV: Musculoskeletal Support and Movement 49. Structure and Function of the Musculoskeletal System 50. Alterations in Musculoskeletal Function: Trauma, Infection, and Disease 51. Alterations in Musculoskeletal Function: Rheumatic Disorders UNIT XV: Integumentary System 52. Alterations in the Integumentary System 53. Burn Injuries Glossary
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