Evolve resources for Aulton's Pharmaceutics: The Design and Manufacture of Medicines, 7th Edition

• Fully updated throughout, with the addition of new chapters, to reflect advances in formulation and drug delivery science, pharmaceutical manufacturing and medicines regulation • Designed and written for newcomers to the design and manufacture of dosage forms • Relevant pharmaceutical science covered throughout • Includes the science of formulation and drug delivery • Reflects current practices and future applications of formulation and drug delivery science to small drug molecules, biotechnology products and nanomedicines • Key points boxes throughout • Over 400 online multiple choice questions

• Updated on COVID in nanomedicines and biologicals

1 Design of dosage forms Part 1 Scientific principles of dosage form design 2 Dissolution and solubility 3 Properties of solutions 4 Surfaces and interfaces 5 Disperse systems 6 Rheology 7 Kinetics Part 2 Particle science and powder technology 8 Solid-state properties 9 Particle size analysis 10 Particle size reduction and size separation 11 Mixing 12 Powder flow Part 3 Pharmaceutical microbiology and sterilization 13 Fundamentals of microbiology 14 Pharmaceutical applications of microbiological techniques 15 Action of physical and chemical agents on microorganisms 16 Principles of sterilization 17 Sterilization in practice Part 4 Biopharmaceutical principles of drug delivery 18 Introduction to biopharmaceutics 19 Gastrointestinal tract – physiology and drug absorption 20 Bioavailability – physicochemical, dosage form and formulation factors 21 Assessment of biopharmaceutical properties 22 Dosage regimens Part 5 Dosage form design and manufacture 23 Pharmaceutical preformulation 24 Solutions 25 Clarification 26 Suspensions 27 Emulsions and creams 28 Ointments, pastes, gels, cutaneous patches and topical sprays 29 Powders, granules and granulation 30 Drying 31 Tablets and compaction 32 Modified-release oral drug delivery 33 Coating of tablets and multiparticulates 34 Continuous manufacturing of tablets 35 Hard capsules 36 Soft capsules 37 Dissolution testing of solid dosage forms 38 Parenteral drug delivery 39 Pulmonary drug delivery 40 Nasal drug delivery 41 Ocular drug delivery 42 Otic drug delivery 43 Topical and transdermal drug delivery 44 Rectal and vaginal drug delivery 45 Preparation and delivery of biopharmaceuticals 46 Pharmaceutical nanotechnology and nanomedicines 47 Radiopharmaceuticals 48 The formulation and manufacture of plant medicines 49 Design and administration of medicines for paediatric and geriatric patients Part 6 Packaging, stability and pharmaceutical regulation 50 Packaging 51 Chemical stability in dosage forms 52 Microbial contamination, spoilage and preservation of medicines 53 Product stability and stability testing 54 Pharmaceutical quality: the application of pharmaceutics in medicines regulation Self-assessment questions

Michael E. Aulton, BPharm, PhD, FAAPS, FSP, FRPharmS, Emeritus Professor, De Montfort University, Leicester, UK and Kevin M.G. Taylor, BPharm PhD FRPharmS, Professor of Clinical Pharmaceutics, UCL School of Pharmacy, London, UK